From hepatic to hematopoietic: LRH‐1's expanding cellular repertoire to the immune system
The FEBS Journal, EarlyView.The nuclear receptor LRH‐1 is a well‐characterized regulator of endodermal tissue. Yet, increasing evidence indicates that LRH‐1, although expressed at low levels, is also a critical regulator of the hematopoietic system. LRH‐1 regulates the immune system by contributing to immune cell‐specific functions.
Lukas Meisinger +3 more
wiley +1 more source
Jejunal mucosal immune response in goats ten months after <i>Mycobacterium avium</i> subsp. <i>paratuberculosis</i> challenge is primarily determined by lesion severity rather than vaccination route. [PDF]
Vet QCriado M +8 more
europepmc +1 more source
A guide to studying tumour‐T‐cell interactions using in vitro coculture assays
The FEBS Journal, EarlyView.In vitro tumour‐T‐cell coculture systems provide a controlled way to study how T cells recognise and kill tumour cells. Different tumour models can be combined with antigen‐specific TCR or CAR T cells, while antigen presentation, cytokines, drugs and tumour genetics can be manipulated.
Nooshin Khoshdoozmasouleh +1 more
wiley +1 more source
The P2X7 receptor: insights from the murine monoclonal antibody clone L4. [PDF]
Purinergic SignalSluyter R +7 more
europepmc +1 more source
International Endodontic Journal, EarlyView.ABSTRACT Aim To evaluate CD68 and F4/80 glycoproteins in the worsening of apical periodontitis (AP) and liver fibrosis (LF) in Wistar rats. Methodology Thirty‐two Wistar rats were distributed in the following groups (n = 8): C—control; AP—apical periodontitis; LF—liver fibrosis; APLF—AP and LF.
L. V. Barroti +9 more
wiley +1 more source
Melatonin and Indole-3-Propionic Acid Reduce Surface FcγRIII/CD16-Related Parameters in Porcine Peripheral Blood Mononuclear Cells In Vitro. [PDF]
Int J Mol SciŚliwka PW +2 more
europepmc +1 more source
Unmasking the Influence of Viral Micro‐RNAs on Host Immunity
Immunology &Cell Biology, EarlyView.Viral micro‐RNAs are increasingly recognized as key modulators of host–virus interactions. They influence multiple immune functions, including antigen presentation, T‐cell activation, and cytokine signaling, while also tuning viral gene expression to promote persistence.
Riley J. K. Easton +1 more
wiley +1 more source
Short-interval longitudinal analysis of immune cell dynamics in heavy draft foals after colostrum intake. [PDF]
J Vet Med SciYoshida S, Takeyama A, Maeda Y, Nambo Y.
europepmc +1 more source
Immunology, EarlyView.Human plasmacytoid dendritic cell‐based vaccines efficiently migrate from blood to lymph nodes and prime naive T cells in humanised mice. Irradiation‐induced CD62L shedding, mediated by p38 MAP kinase and ADAM17, is involved in the regulation of PDC migration to secondary lymphoid organs in this model.
Estelle Leplus +11 more
wiley +1 more source