Results 101 to 110 of about 77,637 (296)

Promotion of Tumor Growth In Vivo by Antimacrophage Agents [PDF]

, 2017
Various attempts were made to assess the role of the mononuclear phagocyte system in tumor resistance of rats in vivo. The growth of sc inoculated, weakly immunogenic, carcinogen-induced, syngeneic tumor cells was modestly reduced by ip injection and ...
Keller, R.
core  

Peritoneal macrophage heterogeneity is associated with different peritoneal dialysis outcomes [PDF]

, 2017
Peritonitis remains the major obstacle for the maintenance of long-term peritoneal dialysis and dysregulated host peritoneal immune responses may compromise local anti-infectious defense, leading to treatment failure.
Andreesen, Ann Kift-Morgan, Aziz, Bellon, Brown, Chia-Te Liao, Davies, Davies, Dioszeghy, Donald J. Fraser, Fakhri, Fielding, Ganguly, Gautier, Geissmann, Gordon, Guilliams, Hume, Hurst, Leah E. Wallace, Li, Liao, Lin, Lin, Malik, McCully, McGregor, McGregor, McLoughlin, Meuter, Mohd Wajid A. Khan, Mokoena, Nicholas Topley, Noorman, Perl, Peterson, Philip R. Taylor, Reimold, Robert Andrews, Roberts, Rosas, Rosas, Sanchez-Sanchez, Satpathy, Segura, Suzuki, Tamoutounour, Verbrugh, Villadangos, Waskow, Xu   +50 more
core   +2 more sources

Photothermal–Immunomodulatory Hydrogel Reinforced by Ti3C2/ZnAl‐LDH Nanoplatform for Eradicating MRSA and Promoting Diabetic Wound Healing

Advanced Science, EarlyView.
A NETs‐inspired Ti3C2/LDH hydrogel integrates trapping, ROS boosting, and M2‐immunomodulation for MRSA‐infected wound repair. ABSTRACT MRSA infections give rise to chronic cutaneous and advance into profound tissue invasions, including osteomyelitis and sepsis—conditions for which existing clinical interventions offer only limited efficacy. The utility
Qiang Shi, Renliang Zhao, Jia Wang, Zhenchen Xiong, Xiangtian Deng, Cheng Zheng, Wenzhi Zhang   +6 more
wiley   +1 more source

Dwellers and Trespassers: Mononuclear Phagocytes at the Borders of the Central Nervous System [PDF]

, 2021
Daniela C. Ivan, Sabrina Walthert, Kristina Berve, Jasmin Steudler, Giuseppe Locatelli   +4 more
openalex   +1 more source

Markers of mouse macrophage development detected by monoclonal antibodies [PDF]

, 1994
In this review, we present and discuss a selected panel of antibody-defined markers expressed during different stages of mouse macrophage ...
Bruijn, M.F.T.R. (Marella) de, Campbell, P.A. (Priscilla), Ewijk, W. (Willem) van, Leenen, P.J.M. (Pieter), Voerman, J.S. (Jane)   +4 more
core   +1 more source

Engineered Small Extracellular Vesicles Targeting Tumor‐Associated Endothelial Cells to Effectively Remodel the Glioma Microenvironment

Advanced Science, EarlyView.
This study developed a novel drug delivery platform that overcomes the blood‐brain barrier in glioblastoma. By fusing IGFBP7 with small extracellular vesicles, the platform specifically targets tumor vasculature. It effectively delivers temozolomide, suppressing tumor growth at low doses.
Lingling Liu, Feiyang Xu, Zhiming Zheng, Xiaodan Yang, Fang Yang, Pei Liu, Yuankun Chen, Yunshu Yang, Junli Zhao, Peiyan Yang, Xiaojing Zheng, Xiaohong Sun, Ping Mao, Qinwen Mao, Hao Guan, Haibin Xia, Weifeng Zhang, Dan Xiao   +17 more
wiley   +1 more source

The trans-sialidase from Trypanosoma cruzi induces thrombocytopenia during acute Chagas' disease by reducing the platelet sialic acid contents [PDF]

, 2005
Strong thrombocytopenia is observed during acute infection with Trypanosoma cruzi, the parasitic protozoan agent of American trypanosomiasis or Chagas' disease.
Campetella, O., Leguizamon, M.S., Mucci, J., Rooijen, N. van, Tribulatti, M.V.   +4 more
core   +2 more sources

Biomimetic Membrane Interface Technologies for Detection and Isolation of CTCs and EVs: Advances and Opportunities in Liquid Biopsy

Advanced Science, EarlyView.
Biomimetic membrane interface engineering constructs functionalized detection platforms by integrating natural cell membranes, synthetic lipids, or hybrid membranes. This strategy effectively reduces background interference and enables efficient target capture and analysis, showing broad applications in circulating tumor cell separation, extracellular ...
Duo Liu, Jie Yu, Jingxue Li, Yixue Chen, Mengle Peng, Yifan Xu, Yongjun Wu, Lihua Ding, Sitian He   +8 more
wiley   +1 more source

Interferon-Regulatory Factors Determine Macrophage Phenotype Polarization

Mediators of Inflammation, 2013
The mononuclear phagocyte system regulates tissue homeostasis as well as all phases of tissue injury and repair. To do so changing tissue environments alter the phenotype of tissue macrophages to assure their support for sustaining and amplifying their ...
Roman Günthner, Hans-Joachim Anders
doaj   +1 more source

Pharmacologic Considerations in the Disposition of Antibodies and Antibody-Drug Conjugates in Preclinical Models and in Patients

Antibodies, 2019
The rapid advancement in the development of therapeutic proteins, including monoclonal antibodies (mAbs) and antibody-drug conjugates (ADCs), has created a novel mechanism to selectively deliver highly potent cytotoxic agents in the treatment of cancer ...
Andrew T. Lucas, Ryan Robinson, Allison N. Schorzman, Joseph A. Piscitelli, Juan F. Razo, William C. Zamboni   +5 more
doaj   +1 more source