Results 141 to 150 of about 77,637 (296)

Poly(2‐Oxazoline)‐Based Polyphotoacids: Synthesis, Solution Behavior, and Cellular Uptake of Multi‐Responsive Intracellular Transporters

Macromolecular Rapid Communications, EarlyView.
The ability of photoacids to increase their acidity in response to light irradiation (excited state proton transfer, ESPT) makes them attractive building blocks for the design of stimuli‐responsive copolymers. In this contribution, we present highly biocompatible polyphotoacids based on poly(2‐oxazoline)s bearing 1‐hydroxypyrene units. Low cytotoxicity,
Leonid I. Kaberov, Amod Godbole, Laura Klement, Sreevalsan Achikkulathu, Avinash Chettri, Benjamin Dietzek‐Ivanšić, Carsten Hoffmann, Felix H. Schacher   +7 more
wiley   +1 more source

Mononuclear Phagocytes, Cellular Immunity, and Nobel Prizes: A Historic Perspective

Cells
The mononuclear phagocyte system includes monocytes, macrophages, some dendritic cells, and multinuclear giant cells. These cell populations display marked heterogeneity depending on their differentiation from embryonic and bone marrow hematopoietic ...
Siamon Gordon, Annabell Roberti, Stefan H. E. Kaufmann   +2 more
doaj   +1 more source

Characterisation of bacteria‐induced colitis and its modulation by probiotics in naked mole rats: a new mammalian model for acute inflammatory disease

The Journal of Pathology, EarlyView.
Abstract Enteropathogenic bacteria are a major cause of morbidity and mortality globally. While mouse models have been indispensable in advancing our understanding of infectious enteric diseases, key differences in intestinal microbiota and immunobiology between mice and humans underscore the need for alternative mammalian models that better ...
Daniel W. Hart, Aik Seng Ng, Patrycja Gazińska, Robert Goldin, Purva Gopal, Nicolize O'Dell, Ahmad Zargar, Lior Pytowski, Shamir Montazid, Chiara Bardella, James E. East, Ian P. Tomlinson, Nadine Koch, Nigel C. Bennett, Shazia Irshad   +14 more
wiley   +1 more source

Induction of inhibitory central nervous system-derived and stimulatory blood-derived dendritic cells suggests a dual role for granulocyte-macrophage colony-stimulating factor in central nervous system inflammation [PDF]

, 2017
The mononuclear phagocyte system, particularly dendritic cells, plays several pivotal roles in the development of multiple sclerosis and its animal model, experimental autoimmune encephalomyelitis.
Fontana, Adriano, Heikenwalder, Mathias, Hesske, Lysann, Prinz, Marco, Reith, Walter, Suter, Tobias, Vincenzetti, Christine   +6 more
core  

Nature Inspired Delivery Vehicles for CRISPR‐Based Genome Editing

Small, EarlyView.
The review highlights nature‐inspired nanocarriers for CRISPR delivery, emphasizing viral vectors, extracellular vesicles, liposomes, and lipid nanoparticles. It discusses their roles in improving specificity, minimizing immunogenicity, and overcoming barriers in genome editing. Recent advancements, challenges, and therapeutic applications are explored,
Elizabeth Maria Clarissa, Mamata Karmacharya, Hyunmin Choi, Sumit Kumar, Yoon‐Kyoung Cho   +4 more
wiley   +1 more source

Leveraging the Mononuclear Phagocyte System for Advancing Glioma Theranostics: Current Insights and Future Directions

Aggregate
Gliomas present a significant challenge in oncology due to their often subtle early symptoms and the insidious nature of their growth, which is compounded by the blood–brain barrier.
Wenhui Wang, Ruijing Wen, Qianbei Li, Zhen Cai, Zihao Ou, Lei Zheng   +5 more
doaj   +1 more source

mononuclear phagocyte system

Citation: 'mononuclear phagocyte system' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.13469 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual ...
openaire   +1 more source

Computational Approach to Identifying Universal Macrophage Biomarkers. [PDF]

, 2020
Macrophages engulf and digest microbes, cellular debris, and various disease-associated cells throughout the body. Understanding the dynamics of macrophage gene expression is crucial for studying human diseases. As both bulk RNAseq and single cell RNAseq
Dang, Dharanidhar, Das, Soumita, Ghosh, Pradipta, Prince, Lawrence S, Sahoo, Debashis, Taheri, Sahar   +5 more
core   +1 more source

Bioengineered Bacterial Vesicles and Biomimetic Hybrids Eliminate Biofilms and Balance the Gut Microbiome

Small, EarlyView.
Biomimetic nanocarriers based on liposomes and Myxobacteria outer‐membrane vesicles (OMVs) are effective antibiotic delivery systems. Hybrids have a higher drug loading and can target intracellular pathogens, while OMVs evade immune clearance. Biomimetic nanoantibiotics effectively eliminate the biofilms of Gram‐negative bacteria. Besides, Myxobacteria
Leila Pourtalebi Jahromi, Benedikt Kronast, Jennifer Munkert, Lorenzo Sana, Marcus Koch, Heike Danzer, Sirka Dormeyer, Shuhan Jiang, Fabian Herrmann, Matthias Weiler, Anna Kashkanova, Vahid Sandoghdar, Mario M. Zaiss, Gregor Fuhrmann   +13 more
wiley   +1 more source

Author response for "The equine mononuclear phagocyte system: the relevance of the horse as a model for understanding human innate immunity"

, 2020
Anna E. Karagianni, Zofia M. Lisowski, David Hume, R. Scott Pirie   +3 more
openalex   +1 more source