Reinforcing the Functionality of Mononuclear Phagocyte System to Control Tuberculosis [PDF]
Frontiers in Immunology, 2018 The mononuclear phagocyte system (MPS) constitutes dendritic cells, monocytes, and macrophages. This system contributes to various functions that are essential for maintaining homeostasis, activation of innate immunity, and bridging it with the adaptive ...
Susanta Pahari +9 more
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Understanding the Cellular Origin of the Mononuclear Phagocyte System Sheds Light on the Myeloid Postulate of Immune Paralysis in Sepsis. [PDF]
Front Immunol, 2018 Sepsis, in essence, is a serious clinical condition that can subsequently result in death as a consequence of a systemic inflammatory response syndrome including febrile leukopenia, hypotension, and multiple organ failures. To date, such life-threatening
Poulin LF, Lasseaux C, Chamaillard M.
europepmc +4 more sources
Gene expression profiling of the Peyer's patch mononuclear phagocyte system [PDF]
Genomics Data, 2015 Peyer's patches (PPs) are primary inductive sites of mucosal immunity. The PP mononuclear phagocyte system, which encompasses both dendritic cells (DCs) and macrophages, is essential for the initiation of the mucosal immune response.
Johnny Bonnardel +5 more
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E-Selectin Ligands in the Human Mononuclear Phagocyte System: Implications for Infection, Inflammation, and Immunotherapy [PDF]
Frontiers in Immunology, 2018 The mononuclear phagocyte system comprises a network of circulating monocytes and dendritic cells (DCs), and “histiocytes” (tissue-resident macrophages and DCs) that are derived in part from blood-borne monocytes and DCs.
Mariana Silva +6 more
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Mononuclear phagocyte system in hepatitis C virus infection. [PDF]
World J Gastroenterol, 2018 The mononuclear phagocyte system (MPS), which consists of monocytes, dendritic cells (DCs), and macrophages, plays a vital role in the innate immune defense against pathogens. Hepatitis C virus (HCV) is efficient in evading the host immunity, thereby facilitating its development into chronic infection.
Yang Y, Tu ZK, Liu XK, Zhang P.
europepmc +4 more sources
<i>Csf1r</i>-mApple Transgene Expression and Ligand Binding In Vivo Reveal Dynamics of CSF1R Expression within the Mononuclear Phagocyte System. [PDF]
J Immunol, 2018 CSF1 is the primary growth factor controlling macrophage numbers, but whether expression of the CSF1 receptor differs between discrete populations of mononuclear phagocytes remains unclear. We have generated a Csf1r-mApple transgenic fluorescent reporter
Hawley CA +12 more
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The development and maintenance of the mononuclear phagocyte system of the chick is controlled by signals from the macrophage colony-stimulating factor receptor. [PDF]
BMC Biol, 2015 Macrophages have many functions in development and homeostasis as well as innate immunity. Recent studies in mammals suggest that cells arising in the yolk sac give rise to self-renewing macrophage populations that persist in adult tissues.
Garceau V +17 more
europepmc +4 more sources
Comparative Study of Nanoparticle Blood Circulation after Forced Clearance of Own Erythrocytes (Mononuclear Phagocyte System-Cytoblockade) or Administration of Cytotoxic Doxorubicin- or Clodronate-Loaded Liposomes. [PDF]
Int J Mol Sci, 2023 Recent developments in the field of nanomedicine have introduced a wide variety of nanomaterials that are capable of recognizing and killing tumor cells with increased specificity.
Mochalova EN +6 more
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CSF1R defines the mononuclear phagocyte system lineage in human blood in health and COVID-19. [PDF]
Immunother Adv, 2021 Summary Mononuclear phagocytes defend tissues, present antigens, and mediate recovery and healing. To date, we lack a marker to unify mononuclear phagocytes in humans or that informs us about their origin. Here, we reassess mononuclear phagocyte ontogeny
Combes TW +6 more
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The Renal Mononuclear Phagocytic System [PDF]
Journal of the American Society of Nephrology, 2011 The renal mononuclear phagocytic system, conventionally composed of macrophages (Mempty set) and dendritic cells (DCs), plays a central role in health and disease of the kidney. Overlapping definitions of renal DCs and M, stemming from historically separate research tracks and the lack of experimental tools to specifically study the roles of these ...
Peter J. Nelson +5 more
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