A hitchhiker's guide to myeloid cell subsets: practical implementation of a novel mononuclear phagocyte classification system [PDF]
The classification of mononuclear phagocytes as either dendritic cells or macrophages has been mainly based on morphology, the expression of surface markers, and assumed functional specialization.
Adams +123 more
core +5 more sources
Langerhans cell histiocytosis as a clonal disease of mononuclear phagocyte system
Langerhans cell histiocytosis (LCH) belongs to histiocytic proliferative diseases, which are rare in clinical practice; however they pose significant challenges both for their diagnosis and choice of therapeutic strategies.
Evgeniy F. Khynku +6 more
doaj +1 more source
Human and mouse mononuclear phagocyte networks: a tale of two species?
Dendritic cells (DCs), monocytes and macrophages are a heterogeneous population of mononuclear phagocytes that are involved in antigen processing and presentation to initiate and regulate immune responses to pathogens, vaccines, tumour and tolerance to ...
Gary eReynolds +2 more
doaj +1 more source
The effect of propylthiouracil on function of phagocytic peripheral blood cells in persons with thyroid hyperfunction [PDF]
Introduction. It is known that hyperthyroidism as well as thyrosuppressive therapy can influence the cells of immunological system. Objective. To examine the function of phagocyte cells in persons with hyperthyroidism and to examine if propylthiouracil ...
Đukić Aleksandar +3 more
doaj +1 more source
Signaling of nicotinic acetylcholine receptors in mononuclear phagocytes
Nicotinic acetylcholine receptors are not only expressed by the nervous system and at the neuro-muscular junction but also by mononuclear phagocytes, which belong to the innate immune system.
Katrin Richter, Veronika Grau
doaj +1 more source
Novel insights into host-fungal pathogen interactions derived from live-cell imaging [PDF]
Acknowledgments The authors acknowledge funding from the Wellcome Trust (080088, 086827, 075470 and 099215) including a Wellcome Trust Strategic Award for Medical Mycology and Fungal Immunology 097377 and FP7-2007–2013 grant agreement HEALTH-F2-2010 ...
A Casadevall +77 more
core +1 more source
Mononuclear phagocytes are organized in a complex system of ontogenically and functionally-distinct subsets, that has been best described in mouse and to some extent in human. Identification of homologous mononuclear phagocyte subsets in other vertebrate
Thien eVu Manh +18 more
doaj +1 more source
Negative Regulation of Semaphorin-3A Expression in Peripheral Blood Mononuclear Cells Using MicroRNA-497-5p [PDF]
Background: Semaphorin-3A (Sema3A), as a secreted semaphorin, is an immune modulator molecule participating in the pathogenesis of autoimmune diseases. MicroRNAs (miRNAs) modulate the target-gene expression at the post-transcriptional level.
Shima Shapoori +6 more
doaj +1 more source
Flt3+ macrophage precursors commit sequentially to osteoclasts, dendritic cells and microglia
Background Macrophages, osteoclasts, dendritic cells, and microglia are highly specialized cells that belong to the mononuclear phagocyte system. Functional and phenotypic heterogeneity within the mononuclear phagocyte system may reveal differentiation ...
Hanau Daniel +15 more
doaj +1 more source

