Results 141 to 150 of about 98,689 (389)

Absence of Neu5Gc and Presence of Anti-Neu5Gc Antibodies in Humans-An Evolutionary Perspective. [PDF]

open access: yes, 2019
The glycocalyx of human cells differs from that of many other mammals by the lack of the sialic acid N-glycolylneuraminic acid (Neu5Gc) and increased abundance of its precursor N-acetylneuraminic acid (Neu5Ac).
Altman, Meghan O, Gagneux, Pascal
core   +1 more source

Flavonoid Profile, Biological Potentials, and In Silico Approaches of Methanol Extracts on AChE: Amaranthus retroflexus L.

open access: yesChemistry &Biodiversity, EarlyView.
ABSTRACT This study investigated the flavonoid compounds and their biological activities in methanol extracts obtained from root, stem, leaf, and flower parts of Amaranthus retroflexus L. Flavonoids in the extracts were characterized for the first time by liquid chromatography–highresolution mass spectrometry (LC–HRMS), and a total of eight flavonoid ...
Bedrettin Selvi   +6 more
wiley   +1 more source

Gold‐Dithiocarbamato Glycoconjugates as Potential Anticancer Agents: Design, Physico‐Chemical Characterization and In Vitro Biological Activity

open access: yesChemBioChem, Accepted Article.
In order to develop new metal‐based glycoconjugates as potential anticancer agents, three gold(III)‐dithiocarbamato glycoconjugates of the type [AuIIIBr2(SSC‐Inp‐GlcN)] (Au3‐5), their gold(I)‐phosphine counterparts [AuI(SSC‐Inp‐GlcN)(PPh3)] (AuP3‐5) and gold(I)‐carbene analogues [AuI(SSC‐Inp‐GlcN)(Et2BzImy)] (AuC3‐5) (Inp: isonipecotic moiety; GlcN ...
Andrea Pettenuzzo   +4 more
wiley   +1 more source

Unveiling the metabolic fate of monosaccharides in cell membranes with glycomic and glycoproteomic analyses. [PDF]

open access: yes, 2019
Cell membrane protein glycosylation is dependent on the metabolic state of the cell as well as exogenous nutrients available. Although the metabolism and interconversion of monosaccharides have been well-studied, their incorporation into cell surface ...
Cheng, Zhi   +5 more
core  

A Purification‐Free Strategy for the Electrochemical Oxidation of the Primary Hydroxy Group in Glycopyranosides

open access: yesChemElectroChem, EarlyView.
A straightforward protocol for the electrochemical oxidation of the primary hydroxy group in glycopyranosides is presented. It uses aqueous ammonia as a base and electrolyte, reticulated vitreous carbon (RVC) electrodes, and TEMPO as a mediator. The ammonium salts of the corresponding uronic acids are obtained in excellent yield upon evaporation of the
Marios Kidonakis   +5 more
wiley   +1 more source

Design of Potent Mannose‐6‐Phosphate Derivatives as Ligands for CI‐M6P/IGF2R Using Fluorescence Polarization Assay

open access: yesChemistry – A European Journal, Volume 31, Issue 41, July 22, 2025.
We designed and synthesized novel mannose‐6‐phosphate (M6P) derivatives to enhance their binding affinity for the CI‐M6P/IGF2 receptor, which plays a key role in lysosomal targeting. Using a fluorescence polarization assay, we evaluated di‐, tri‐, and penta‐M6P peptides and modified M6P analogs.
Lucie Mrázková   +11 more
wiley   +1 more source

Acceptor‐Adaptive Automated Glycosylation Optimization for Automated Glycan Assembly

open access: yesChemistry – A European Journal, EarlyView.
The difficulty of finding the optimal glycosylation conditions for automated solid‐phase glycan assembly leads to the use of large temperature ranges and excess reagents. This has negative atom and energy efficiency implications. We demonstrate that mirroring glycosylation temperature from solution to solid phase via an automated acceptor‐adaptive ...
Yasmeen Bakhatan   +5 more
wiley   +1 more source

Sustainable Hydrogen Production by Glycerol and Monosaccharides Catalytic Acceptorless Dehydrogenation (AD) in Homogeneous Phase

open access: yesChemSusChem, Volume 18, Issue 6, March 15, 2025.
Sustainable hydrogen production can be obtained from hydogen‐rich biomass‐derived organic molecules through Acceptorless Dehydrogenation (AD) reactions. Glycerol and sugars are available in large quantities from industry and can be successfully used as substrates in AD protocols, in the presence of tailored, selective, easily tunable and thermally ...
Sylwia Kostera, Luca Gonsalvi
wiley   +1 more source

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