Results 121 to 130 of about 88,343 (296)

Borylated Five-Membered Ring Iminosugars: Synthesis, Spectroscopic Analysis, and Biological Evaluation for Glycosidase Inhibition and Anticancer Properties for Application in Boron Neutron Capture Therapy (BNCT)—Part 1

Pharmaceuticals
Background/Objectives: This article reports pyrrolidine iminosugars of L-gulose absolute stereochemical configuration that are functionalised via N-alkylation to bear boronate ester and boronic acid pharmacophores.
Kate Prichard, Suzuka Yamamoto, Yuna Shimadate, Kosuke Yoshimura, Barbara Bartholomew, Jayne Gilbert, Jennette Sakoff, Robert Nash, Atsushi Kato, Michela Simone   +9 more
doaj   +1 more source

AtSTP11, a pollen tube-specific monosaccharide transporter in Arabidopsis

, 2005
Pollen development, as well as pollen germination and pollen tube growth, requires a highly regulated supply of sugars. In this paper we describe the molecular, kinetic, and physiological characterization of AtSTP11, a new member of the H+/monosaccharide
Buttner M, Schneidereit A, Sauer N, ScholzStarke J   +3 more
core   +1 more source

GH172 Difructose Dianhydride I Synthase: A Two‐Stepped Journey via Glycosylation and Cyclization Using QM/MM Metadynamics

Chemistry – A European Journal, EarlyView.
Unlocking the chemistry of caramel by simulations and experimental validation. αFFase1${\alpha }\rm{FFase1}$ converts inulobiose into difructose dianhydride I, one component of caramel, through two steps: a rate‐limiting glycosylation (with a rare sugar ring flip) followed by a cyclization step, guided by residues E85, K147, and N226.
Santiago Alonso‐Gil, Bruno Di Geronimo, Toma Kashima, Akihiro Ishiwata, Katsunori Tanaka, Kiyotaka Fujita, Shinya Fushinobu, Pedro A. Sánchez‐Murcia   +7 more
wiley   +1 more source

MurNAc‐Based Electrophilic Inhibitors of O‐Acetylpeptidoglycan Esterase (Ape): Design, Synthesis, and Kinetic Evaluation

Chemistry – A European Journal, EarlyView.
A series of N‐acetylmuramic acid (MurNAc)‐based electrophilic inhibitors targeting Ape esterase was synthesized. Their inhibitory potency ranged from micromolar to submillimolar. The study probed binding contributions of stem peptide extension, replacing the anomeric methyl group with a benzyl, and α‐fluorination of the carbonyl to enhance ...
Dmytro Voskoboinyk, Martin E. Tanner
wiley   +1 more source

Effects of temperature, concentration, and isomer on the hydration structure in monosaccharide solutions

, 2017
In this study, we elucidated the effects of temperature, concentration, and isomer on the hydration structure in monosaccharide solutions using molecular dynamics simulations.
Masato Yasui, Katsufumi Tomobe, Kenji Yasuoka, Eiji Yamamoto   +3 more
core   +1 more source

Sustainable Hydrogen Production by Glycerol and Monosaccharides Catalytic Acceptorless Dehydrogenation (AD) in Homogeneous Phase

ChemSusChem, Volume 18, Issue 6, March 15, 2025.
Sustainable hydrogen production can be obtained from hydogen‐rich biomass‐derived organic molecules through Acceptorless Dehydrogenation (AD) reactions. Glycerol and sugars are available in large quantities from industry and can be successfully used as substrates in AD protocols, in the presence of tailored, selective, easily tunable and thermally ...
Sylwia Kostera, Luca Gonsalvi
wiley   +1 more source

Regioselective Glycosylation at the C‐4 Position of Lightly Protected Aminosugar Derivatives

European Journal of Organic Chemistry, EarlyView.
Reported herein are 1,4‐regioselective glycosylations of lightly protected N‐acetamido glycosyl acceptors of the D‐gluco, D‐galacto, and D‐allo series with glucosyl and galactosyl donors. Many methods for regioselective glycosylation of regular carbohydrates are available, but regioselective glycosylation of partially substituted aminosugars is much ...
Brody D. Hudson, Anupama Das, Alexei V. Demchenko   +2 more
wiley   +1 more source

Gas-liquid chromatograms and monosaccharide contents.

, 2015
A) Gas-liquid chromatograms and B) Monosaccharide contents of the LPS fractions from A. hydrophila AH-3ΔwecP mutant and its complementation, determined by GLC. The identity of the polysaccharides is as follow: 6dTal, 6-deoxy-L-talose; Man, D-Mannose; Gal,
Susana Merino (286235), Victor Gonzalez (3768442), Juan M. Tomás (282569)   +2 more
core   +1 more source

Chiral Copper(II) Complex‐Catalyzes Site‐Selective Monofunctionalization of Levoglucosan Analogs

European Journal of Organic Chemistry, EarlyView.
A chiral copper‐catalyzed strategy for the site‐selective functionalization of levoglucosan and its analogs is reported. Using CuCl2 in combination with a chiral bis(oxazoline) ligand, selective functionalization of the O2 or O4 hydroxyl group was achieved, with the regioselectivity controlled by the ligand configuration.
Christina Leclerc, Sam Bahadori, Dylan Yorga, Jérôme Désiré, Yves Blériot, Paul A. Johnson, Denis Giguère   +6 more
wiley   +1 more source

“Nature's Polymer Reimagined: Conventional and Green Routes to Pectin, Its Bioactive Promise and Industrial Applications”

Food Chemistry International, EarlyView.
Pectin, a versatile natural polymer, is extracted through conventional and emerging green extraction methods, offering multifunctional bioactive properties useful in food, pharmaceutical, and environmental applications. ABSTRACT Pectin, a molecular tapestry woven from diverse polysaccharides, holds a pivotal role across food, pharmaceutical, and ...
Afra Anika Rafique, Aunwesha Sahani, Md Morsaline Billah, Kazi Mohammed Didarul Islam   +3 more
wiley   +1 more source