Results 101 to 110 of about 88,343 (296)

Stabilization by Crosslinking of β‐Galactosidase Immobilized by Adsorption for Application in a Continuous Lactose Removal Process

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Adsorption is the simplest method of enzyme immobilization, but it often requires additional treatments to improve stability. These treatments, however, may impact enzymatic activity. This study investigated the effect of crosslinking on the stability of β‐galactosidase immobilized by adsorption on A‐568 resin and its implications for ...
Aliou Toro Lafia, Adrielle Aparecia Paulista Ribeiro, Larissa Nayhara Soares Santana Falleiros, Carla Zanella Guidini   +3 more
wiley   +1 more source

Biomanufacturing of L‐Lactic Acid from Inulin Exploiting Kluyveromyces marxianus and Engineered Saccharomyces cerevisiae Cell Factories

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT The transition to sustainable lactic acid (LA) biomanufacturing necessitates a shift from first‐generation feedstocks toward residual biomass and low‐pH fermentation, eliminating the costly, waste‐intensive salt purification and acidification steps. This study presents a novel, two‐yeast strategy designed to valorize inulin, a fructose polymer
Riccardo Milanesi, Raffaella Desirè Di Lorenzo, Danilo Porro, Paola Branduardi, Immacolata Serra   +4 more
wiley   +1 more source

Synthesis, helicity, and biological properties of monosaccharide-containing poly(phenylacetylene)s

, 2007
Poly(phenylacetylene)s bearing monosaccharide pendant groups are synthesized in high yields by [Rh(nbd)Cl]2 catalyst. The polymers have high molecular weights and give satisfactory spectroscopic data corresponding to their molecular structures.
Cheuk, Kevin K.L., Li, Bing Shi, Lam, Jacky W.Y., Xie, Yong, Tang, Ben Zhong   +4 more
core   +1 more source

Pharmacokinetic and pharmacodynamic interaction of enavogliflozin, a sodium‐glucose cotransporter 2 inhibitor, with glimepiride and metformin in healthy participants

British Journal of Clinical Pharmacology, EarlyView.
Aims Enavogliflozin, a sodium‐glucose cotransporter 2 inhibitor, is expected to be coadministered with antihyperglycaemic drugs with different mechanisms of action. This study aimed to investigate the pharmacokinetic (PK) and pharmacodynamic (PD) interactions between enavogliflozin, glimepiride and metformin.
Kyungrin Chang, Yoonjin Kim, Daye Jung, Jae Min Cho, Joo‐Youn Cho, SeungHwan Lee   +5 more
wiley   +1 more source

Borylated 5-Membered Ring Iminosugars: Synthesis and Biological Evaluation for Glycosidase Inhibition and Anticancer Properties for Application in Boron Neutron Capture Therapy (BNCT)—Part 2

Pharmaceuticals
Background: The synthesis and biological investigation of pyrrolidine (L-gulo) iminosugars bearing an organic boron pharmacophore in ortho and meta positions of an N-benzyl group is reported.
Kate Prichard, Kosuke Yoshimura, Suzuka Yamamoto, Atsumi Taguchi, Barbara Bartholomew, Jayne Gilbert, Jennette Sakoff, Robert Nash, Atsushi Kato, Michela Simone   +9 more
doaj   +1 more source

Gas chromatogram of standard monosaccharide (a) and alditol acetate derivatives from ETH-2 (b).

, 2014
Gas chromatogram of standard monosaccharide (a) and alditol acetate derivatives from ETH-2 (b).
Dou Li (671705), Wei Tang (53470), Liyan Song (671704), Heping Zhao (671708), Jing Qiao (671706), Tiantao Zhao (671707)   +5 more
core   +1 more source

Combinatorial Metabolic Engineering of Alkane Biosynthesis in the Osmotolerant Yeast Debaryomyces hansenii CBS 767

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Debaryomyces hansenii is a yeast with diverse potential applications like producing oleochemicals from biomass. Yet, combinatorial metabolic engineering in D. hansenii is limited because, like many nonconventional organisms, key genomic data and genetic elements are missing. Here, we report phenotypic characterization, genomic integration loci,
Zekun Li, Nilesh Kumar Sharma, Sarah Weintraub, Eric Young   +3 more
wiley   +1 more source

HPAEC quantification of monosaccharide and sialic acid released after acid hydrolysis of affinity purified PI-2a pili from S. agalactiae strain NEM316.

, 2015
*Mean ± SD** Not detectedLimit of detection: 0.1 μg/mL for each monosaccharide.HPAEC quantification of monosaccharide and sialic acid released after acid hydrolysis of affinity purified PI-2a pili from S. agalactiae strain NEM316.
Adeline Mallet (228693), Michel-Yves Mistou (158946), Liliana Oliveira (186914), Giulia Oliva (800176), Anne-Marie Di Guilmi (550002), Thibault Chaze (800175), Eric Morello (176746), Shaynoor Dramsi (158929), Patrick Trieu-Cuot (137125), Yoan Konto-Ghiorghi (264435)   +9 more
core   +1 more source

Glycosylated dendrimer nanoamplifiers hijack DNA damage‐immune crosstalk for enhanced dual‐track therapy of orthotopic glioblastoma

BMEMat, EarlyView.
A glycosylated dendrimer nanoamplifier hijacks DNA damage‐immune crosstalk for enhanced radio‐immunotherapy of glioblastoma. The responsive release of demethylcantharidin simultaneously blocks repair‐mediated resistance by inhibiting DNA repair and overcomes adaptive immune resistance.
Cong Song, Binghan Liu, Junjie Liu, Ce Li, Wenqing Man, Xurui Sun, Chang Yuan, Yanjun Wang, Hong Pan, Shuanglian Wang, Zhiming Zheng   +10 more
wiley   +1 more source

PURIFICATION AND ANALYSIS OF CARBOHYDRATE CLUSTER FROM ERYTHROPOIETIN RECOMBINANT EXPRESSION RESULT ON THE LEAVEN SYSTEM OF Pichia pastoris

Makara Seri Sains, 2011
For clinical purposes, pure protein and identification of carbohydrate structure from erythropoietin recombinant are needed. Purification was done with His-Trap affinity chromatography method and continued with gel filtration chromatography column to get
Adi Santoso, Andri Wardiana
doaj