A practical way to synthesize chiral fluoro-containing polyhydro-2H-chromenes from monoterpenoids
Conditions enabling the single-step preparative synthesis of chiral 4-fluoropolyhydro-2H-chromenes in good yields through a reaction between monoterpenoid alcohols with para-menthane skeleton and aldehydes were developed for the first time.
Oksana S. Mikhalchenko +3 more
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Two novel structural types of tyrosyl-DNA phosphodiesterase 1 (TDP1) inhibitors with hexahydroisobenzofuran 11 and 3-oxabicyclo [3.3.1]nonane 12 scaffolds were discovered.
Irina V. Il’ina +17 more
doaj +1 more source
Terzyme: a tool for identification and analysis of the plant terpenome. [PDF]
BACKGROUND: Terpenoid hydrocarbons represent the largest and most ancient group of phytochemicals, such that the entire chemical library of a plant is often referred to as its 'terpenome'.
core +3 more sources
Cardiovascular Activity of the Chemical Constituents of Essential Oils
Cardiovascular diseases are a leading cause of death in developed and developing countries and decrease the quality of life, which has enormous social and economic consequences for the population. Recent studies on essential oils have attracted attention
Tadeu Uggere de Andrade +4 more
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(1R,2R,6S)-2(4-(4-Isopropylbenzyl)piperazin-1-yl)-3-methyl-6-(prop-1-en-2-yl)cyclohex-3-enol
Parkinson’s disease (PD) is a progressive neurodegenerative disorder mainly characterized by movement dysfunction. Earlier, it was found that (1R,2R,6S)-3-methyl-6-(prop-1-en-2-yl)cyclohex-3-ene-1,2-diol (Prottremin) demonstrated antiparkinsonian ...
Alexandra V. Podturkina +3 more
doaj +1 more source
Direct Injection Liquid Chromatography High-Resolution Mass Spectrometry for Determination of Primary and Secondary Terrestrial and Marine Biomarkers in Ice Cores [PDF]
Many atmospheric organic compounds are long-lived enough to be transported from their sources to polar regions and high mountain environments where they can be trapped in ice archives.
Bogialli, S. +8 more
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The mosquito Aedes aegypti is a major threat to public health because it spreads several arboviruses. Since this insect is an anthropophilic mosquito that has evolved to thrive in urban settings and is common in Brazil and other tropical nations ...
G.J. Nascimento +4 more
doaj +1 more source
Iridoid glucosides from Pentas lanceolata (Forssk.) Deflers growing on the Island of Sardinia [PDF]
The ethanolic extract of Pentas lanceolata (Forssk.) Deflers was investigated from a phytochemical point of view and in particular on the monoterpenoid glucosides content.
Bianco, Armandodoriano +3 more
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Anthropogenic monoterpenes aggravating ozone pollution
Abstract Monoterpenes have been known to have a critical influence on air quality and climate change through their impact on the formation of fine particles. Here we present field evidence that monoterpene oxidations largely enhanced local ozone production in a regional site in eastern China. The observed monoterpene was most likely from
Haichao Wang +14 more
openaire +3 more sources
Pd(OAc)2/Ph3P-catalyzed dimerization of isoprene and synthesis of monoterpenic heterocycles
The palladium-catalyzed dimerization of isoprene is a practical approach of synthesizing monoterpenes. Though several highly selective methods have been reported, most of them still required pressure or costly ligands for attaining the active system and ...
Dominik Kellner +3 more
doaj +1 more source

