Results 121 to 130 of about 27,891 (280)

Therapeutic effect of budesonide, montelukast and azithromycin on post-infectious bronchiolitis obliterans in children

open access: yesExperimental and Therapeutic Medicine, 2020
Optimal treatment options for post-infectious bronchiolitis obliterans (PIBO) have not yet been established. The present study retrospectively analyzed the effect of budesonide, montelukast and azithromycin on treating PIBO in children
Xia Chen   +4 more
semanticscholar   +1 more source

Investigation of the bioequivalence of montelukast chewable tablets after a single oral administration using a validated LC-MS/MS method [PDF]

open access: yes, 2015
Background: Montelukast (MT) is a leukotriene D4 antagonist. It is an effective and safe medicine for the prophylaxis and treatment of chronic asthma. It is also used to prevent acute exercise-induced bronchoconstriction and as a symptomatic relief of ...
Abualhasan, Murad N   +5 more
core   +1 more source

A Phenotyping Tool for Seven Cytochrome P450 Enzymes and Two Transporters: Application to Examine the Effects of Clopidogrel and Gemfibrozil

open access: yesClinical Pharmacology &Therapeutics, Volume 117, Issue 6, Page 1732-1742, June 2025.
Clinical cocktails for cytochrome P450 (CYP) phenotyping lack a marker for CYP2C8. We aimed to combine the CYP2C8 index drug repaglinide with the Geneva cocktail (caffeine/CYP1A2, bupropion/CYP2B6, flurbiprofen/CYP2C9, omeprazole/CYP2C19, dextromethorphan/CYP2D6, and midazolam/CYP3A4). We also included endogenous organic anion transporting polypeptide (
Laura Aurinsalo   +7 more
wiley   +1 more source

Monitoring asthma in childhood : Lung function, bronchial responsiveness and inflammation [PDF]

open access: yes, 2015
Peer reviewedPublisher ...
ERS Task Force Monitoring Asthma in Children
core   +1 more source

Efficacy of Intravenous Methylprednisolone Pulses in Children With Postinfectious Bronchiolitis Obliterans

open access: yesPediatric Pulmonology, Volume 60, Issue 6, June 2025.
ABSTRACT Objective To assess the efficacy of intravenous methylprednisolone pulses in children with postinfectious bronchiolitis obliterans (PIBO). Study Design/Methods This French monocentric retrospective study included 31 patients with PIBO. Respiratory symptoms, occurrence of exacerbations and hospitalizations up to 4 years, and the results of lung
Souad Ghattas   +2 more
wiley   +1 more source

lncRNA PCGEM1 strengthens anti-inflammatory and lung protective effects of montelukast sodium in children with cough-variant asthma

open access: yesBrazilian Journal of Medical and Biological Research
Montelukast sodium is an effective and well-tolerated anti-asthmatic drug. Long non-coding RNAs (lncRNAs) are involved in the treatment of asthma. Therefore, this study aimed to investigate the effect of montelukast sodium on children with cough-variant ...
Zhenxing Xu   +3 more
doaj   +1 more source

The effect of montelukast on exhaled nitric oxide of alveolar and bronchial origin in inhaled corticosteroid-treated asthma [PDF]

open access: yes, 2009
SummaryBackgroundInhaled corticosteroid therapy suppresses nitric oxide levels (NO) of airway origin but not necessarily NO of alveolar or small airway origin.
Chapman, Kenneth R.   +3 more
core   +1 more source

Pediatric severe asthma: A case series report and perspectives on anti-IgE treatment [PDF]

open access: yes, 2018
Background The primary goal of asthma management is to achieve disease control for reducing the risk of future exacerbations and progressive loss of lung function. Asthma not responding to treatment may result in significant morbidity.
Mirra, Virginia   +2 more
core   +1 more source

APPLICATION EFFICIENCY OF MONTELUKAST AMONG CHILDREN SUFFERING FROM BRONCHIAL ASTHMA

open access: yesПедиатрическая фармакология, 2008
The article provides the results of montelukast efficiency depending on bronchial asthma severity level and the duration of a disease; the assessment of functional figures dynamics, disease pattern before and after the treatment with montelukast and the ...
A.K. Gevorkyan, E.A. Galeeva
doaj   +2 more sources

Add-on montelukast in inadequately controlled asthma patients in a 6-month open-label study: The MONtelukast In Chronic Asthma (MONICA) study [PDF]

open access: yes, 2010
SummaryBronchial asthma often remains uncontrolled despite treatment with inhaled corticosteroids (ICS), long-acting β2-agonists (LABA) or both, necessitating additional treatment.
Ljungblad, Li   +3 more
core   +1 more source

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