Results 141 to 150 of about 617,785 (192)

Machine learning-based discovery of GW3965 as a therapeutic compound against invasive emm92-type group A Streptococcus. [PDF]

NPJ Antimicrob Resist
Powell LM, Grund ME, Shi W, Choi SJ, Zelaya K, Bobbala S, Geldenhuys W, Barbier M, LaSala PR, Lukomski S.   +9 more
europepmc   +1 more source

Drug-induced urinary incontinence in pediatric patients: A disproportionality analysis of the FDA Adverse Event Reporting System. [PDF]

Medicine (Baltimore)
Jin C, Zhang X, Ouyang X, Lou Q.
europepmc   +1 more source

pK a Determinations for Montelukast Sodium and Levodropropizine

Journal of Solution Chemistry, 2010
The pK a constants and relative abundances of unionized and ionized forms of Montelukast sodium {the sodium salt of 2-[1-[[(1R)-1-[3-[2-(7-chloroquinolin-2-yl)ethenyl] phenyl]-3-[2-(2-hydroxypropan-2-yl)phenyl]propyl]sulfanylmethyl]cyclopropyl]acetic acid} and Levodropropizine {(2S)-3-(4-phenylpiperazin-1-yl)propane-1,2-diol ...
Sarı, Hayati, NARİN, Ibrahim, Anilanmert, Beril, Saroğlan, Salih   +3 more
openaire   +4 more sources

Comparison of Cromolyn Sodium, Montelukast, and Zafirlukast Prophylaxis for Capsular Contracture

Plastic & Reconstructive Surgery, 2022
Background: Capsular contracture is the most common complication following breast augmentation. Recently, prophylaxis studies aiming to inhibit the release of profibrotic substances to prevent capsular contracture have gained in importance.
Üstün, GALİP GENCAY, Kösemehmetoğlu, KEMAL, Uzun, Hakan, Boynuyoğun, Etkin, Ispirli, Mukaddes, Menkü Özdemir, Fethiye Damla   +5 more
openaire   +4 more sources

An Enantioselective Formal Synthesis of Montelukast Sodium

The Journal of Organic Chemistry, 2015
A formal synthesis of the antiasthma drug montelukast sodium is described, wherein the key chiral diol intermediate was accessed with greater convergence of the C-C bond-forming steps as compared to previous routes. Improved synthetic efficiency was achieved by deploying homogeneous metal-based catalysis in two pivotal steps.
Satyanarayana, Bollikonda, Saravanan, Mohanarangam, Rajender Reddy, Jinna, Venkata Kiran Kumar, Kandirelli, Laxman, Makthala, Saikat, Sen, David A, Chaplin, Richard C, Lloyd, Thomas, Mahoney, Vilas Hareshwar, Dahanukar, Srinivas, Oruganti, Martin E, Fox   +11 more
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Determination of Montelukast Sodium by Capillary Electrophoresis

Journal of Separation Science, 2008
AbstractThis work verifies the potential of CE in the analysis of significant impurities of montelukast sodium – an active ingredient for the treatment of bronchial asthma. Using 20 mM borate buffer pH 9.2 with 10 mM SDS and 10 mM (2‐hydroxypropyl)‐γ‐CD (2HP‐γ‐CD) it was possible to separate montelukast and several impurities, including its cis‐isomer,
Yuliya Shakalisava, Fiona Regan
exaly   +3 more sources

An Analytical Review for the Estimation of Montelukast Sodium

Separation Science Plus, 2022
Abstract Montelukast is a highly potent and selective receptor antagonist of cysteinyl leukotrienes (CysLT1) used in chronic asthma and vasoconstriction reduction and also used in allergies, swelling, hay fever, and shortness of breath.
Balak Das Kurmi, Ghanshyam Das Gupta, Vivek Asati   +2 more
exaly   +2 more sources

Pharmacokinetics, Bioavailability, and Safety of Montelukast Sodium (MK-0476) in Healthy Males and Females

Pharmaceutical Research, 1996
Purpose. The safety, tolerability, and pharmacokinetics of intravenous (i.v.) montelukast sodium (Singulair®, MK-0476), and the oral bioavailability of montelukast sodium in healthy males and healthy females were studied. Methods.
Jonathan A Leff, Haiyung Cheng, J D Rogers   +2 more
exaly   +2 more sources

Montelukast sodium for exercise-induced asthma

Drugs of Today, 2008
Exercise is the most common trigger of bronchospasm in children with asthma. Exercise-induced bronchoconstriction (EIB) occurs in up to 90% of individuals with asthma who are not under antiinflammatory treatment and in about 40% of those with allergic rhinitis. EIB may be an overwhelming problem in childhood and adolescence, when physical activity is a
Fernando Maria, de Benedictis, Silvia, Vaccher, Diletta, de Benedictis   +2 more
openaire   +2 more sources

Formulation and evaluation of orodispersible tablet of montelukast sodium

Research Journal of Pharmacy and Technology, 2018
The objective of the current study was to develop and optimize an orodispersible tablet formulation of montelukast sodium which is an effective drug in the treatment of asthma and allergic disorders. Montelukast sodium is the drug used in treatment of ashthmatic and allergicrhinitis; it is selective leukotrienesreceptor antagonist.
Siddharth Kumar Sahu, null Ajazuddin, Tripti Banjare, Swapnil Gupta, Akansha Bhandarkar, Hemlata Sahu, Shradha Devi Diwedi, Pankaj Sahu, Palak Agrawal, Pooja Yadav, Aditi Bhatt, Kailash Sahu, Deeksha Dewangan, Hemlata Thapa, null Deepika, Gyanesh Sahu, Mukesh Sharma, D. K. Tripathi, Amit Alexander   +18 more
openaire   +1 more source