Results 11 to 20 of about 533 (123)

Supramolecular Engineering of Nanoceria for Management and Amelioration of Age‐Related Macular Degeneration via the Two‐Level Blocking of Oxidative Stress and Inflammation [PDF]

Advanced Science
Age‐related macular degeneration (AMD), characterized by choroidal neovascularization (CNV), is the global leading cause of irreversible blindness.
Mingyu Xu, Yifan Zhou, Yufeng Xu, An Shao, Haijie Han, Juan Ye   +5 more
doaj   +3 more sources

Human gingival mesenchymal stem cells pretreated with vesicular moringin nanostructures as a new therapeutic approach in a mouse model of spinal cord injury [PDF]

Journal of Tissue Engineering and Regenerative Medicine, Volume 13, Issue 7, Page 1109-1121, July 2019., 2019
Spinal cord injury (SCI) is a neurological disorder that arises from a primary acute mechanical lesion, followed by a pathophysiological cascade of events that leads to further spinal cord tissue damage.
Bramanti, Placido, Cavalli, Eugenio, Conti, Pio, Diomede, Francesca, Fontana, Antonella, Gugliandolo, Agnese, Iori, Renato, Mammana, Santa, Mazzon, Emanuela, Pizzicannella, Jacopo, Zappacosta, Romina   +10 more
core   +6 more sources

α-Cyclodextrin/Moringin Induces an Antioxidant Transcriptional Response Activating Nrf2 in Differentiated NSC-34 Motor Neurons [PDF]

Antioxidants
Oxidative stress is a common feature of neurodegenerative diseases. Different natural compounds mediate neuroprotective effects by activating the Nrf2 antioxidant response. Some isothiocyanates are Nrf2 activators, including Moringin (MOR). In this study,
Agnese Gugliandolo, Gabriella Calì, Claudia Muscarà, Osvaldo Artimagnella, Patrick Rollin, Daniele Perenzoni, Renato Iori, Emanuela Mazzon, Luigi Chiricosta   +8 more
doaj   +5 more sources

Moringin Pretreatment Inhibits the Expression of Genes Involved in Mitophagy in the Stem Cell of the Human Periodontal Ligament [PDF]

Molecules, 2019
Moringin [4-(α-L-rhamnosyloxy) benzyl isothiocyanate] is an isothiocyanate extracted from Moringa oleifera seeds. It is an antioxidant known for several biological properties useful in the treatment of neurodegenerative diseases.
Luigi Chiricosta, Agnese Gugliandolo, Francesca Diomede, Jacopo Pizzicannella, Oriana Trubiani, Renato Iori, Giuseppe Tardiolo, Simone Guarnieri, Placido Bramanti, Emanuela Mazzon   +9 more
doaj   +5 more sources

The Chemopreventive Phytochemical Moringin Isolated from Moringa oleifera Seeds Inhibits JAK/STAT Signaling. [PDF]

PLoS ONE, 2016
Sulforaphane (SFN) and moringin (GMG-ITC) are edible isothiocyanates present as glucosinolate precursors in cruciferous vegetables and in the plant Moringa oleifera respectively, and recognized for their chemopreventive and medicinal properties.
Carina Michl, Fabio Vivarelli, Julia Weigl, Gina Rosalinda De Nicola, Donatella Canistro, Moreno Paolini, Renato Iori, Anne Rascle   +7 more
doaj   +5 more sources

Methodology for rapid isolation of Moringin: Potential anticancer compound from the seeds of Moringa stenopetala [PDF]

Pharmaceutica Analytica Acta, 2017
The seeds of Moringa stenopetala which are known to be rich sources of glucosinolates, primarily glucomoringin, have been shown to have limited anticancer effects when tested in vitro.
Habtemariam, Solomon
core   +3 more sources

The α-Cyclodextrin/Moringin Complex: A New Promising Antimicrobial Agent against Staphylococcus aureus [PDF]

Molecules, 2018
Antimicrobial resistance is one of the major clinical concerns, making the discovery of new antimicrobial drugs desirable. Moringin (MOR), the major isothiocyanate produced from Moringa oleifera seeds, could represent an alternative therapeutic strategy ...
Letizia Romeo, Veronica Lanza Cariccio, Renato Iori, Patrick Rollin, Placido Bramanti, Emanuela Mazzon   +5 more
doaj   +3 more sources

Transcriptomic Analysis of Stem Cells Treated with Moringin or Cannabidiol: Analogies and Differences in Inflammation Pathways [PDF]

International Journal of Molecular Sciences, 2019
Inflammation is a common feature of many neurodegenerative diseases. The treatment of stem cells as a therapeutic approach to repair damage in the central nervous system represents a valid alternative. In this study, using Next-Generation Sequencing (NGS)
Bramanti P., Chiricosta L., Diomede F., Mazzon E., Pizzicannella J., Silvestro S., Trubiani O.   +6 more
core   +5 more sources

A Combined Approach of NMR and Mass Spectrometry Techniques Applied to the α-Cyclodextrin/Moringin Complex for a Novel Bioactive Formulation † [PDF]

Molecules, 2018
Moringin, obtained via enzymatic conversion of the glucosinolate precursor glucomoringin, is an uncommon member of the isothiocyanate class, and has been proven to possess a broad range of biological activities such as antitumor activity, protection ...
David Mathiron, Renato Iori, Serge Pilard, Thangavelu Soundara Rajan, David Landy, Emanuela Mazzon, Patrick Rollin, Florence Djedaïni-Pilard   +7 more
doaj   +3 more sources

The role of isothiocyanate-rich plants and supplements in neuropsychiatric disorders: a review and update. [PDF]

Front Nutr
Neuroinflammation in response to environmental stressors is an important common pathway in a number of neurological and psychiatric disorders. Responses to immune-mediated stress can lead to epigenetic changes and the development of neuropsychiatric ...
Ramakrishnan M, Fahey JW, Zimmerman AW, Zhou X, Panjwani AA.   +4 more
europepmc   +3 more sources