Results 21 to 30 of about 350 (108)

α-Cyclodextrin/Moringin Impacts Actin Cytoskeleton Dynamics with Potential Implications for Synaptic Organization: A Preliminary Transcriptomic Study in NSC-34 Motor Neurons [PDF]

International Journal of Molecular Sciences
α-Cyclodextrin/Moringin (α-CD/MOR) is an isothiocyanate showing neuroprotective and antioxidant properties. In this work, we studied in differentiated NSC-34 motor neurons cell line the molecular pathways activated following a treatment of 96 h with α-CD/MOR at different doses, namely 0.5, 5 and 10 μM.
Patrick Rollin, Emanuela Mazzon, Agnese Gugliandolo   +2 more
exaly   +4 more sources

An insight into the neuroprotective and anti-neuroinflammatory effects and mechanisms of Moringa oleifera [PDF]

Frontiers in Pharmacology, 2023
Neurodegenerative diseases (NDs) are sporadic maladies that affect patients’ lives with progressive neurological disabilities and reduced quality of life.
Ummi Kalthum Azlan, Nur Aisyah Khairul Annuar, Ahmed Mediani, Wan Mohd Aizat, Hanafi Ahmad Damanhuri, Xiaohui Tong, Daijiro Yanagisawa, Ikuo Tooyama, Wan Zurinah Wan Ngah, Ibrahim Jantan, Hamizah Shahirah Hamezah   +10 more
doaj   +2 more sources

Moringin from Moringa Oleifera Seeds Inhibits Growth, Arrests Cell-Cycle, and Induces Apoptosis of SH-SY5Y Human Neuroblastoma Cells through the Modulation of NF-κB and Apoptotic Related Factors. [PDF]

Int J Mol Sci, 2019
In the last decades, glucosinolates (GLs), precursors of isothiocyanates (ITCs), have been studied mostly for their chemopreventive and chemotherapeutic properties.
Cirmi S, Ferlazzo N, Gugliandolo A, Musumeci L, Mazzon E, Bramanti A, Navarra M.   +6 more
europepmc   +7 more sources

Moringa oleifera Use in Maintaining Oral Health and Its Potential Use in Regenerative Dentistry. [PDF]

ScientificWorldJournal, 2023
Phytomedicine refers to the use of naturally derived products to cure and mitigate human conditions. Natural products have the advantages of causing minimum side effects, being biocompatible, available, and economical, with a wide array of biological activities. Reports have described the use of natural products with antimicrobial and anti‐inflammatory
Shafiq NE, Mahdee AF.
europepmc   +2 more sources

Anti-inflammatory and antioxidant effects of a combination of cannabidiol and moringin in LPS-stimulated macrophages

Fitoterapia, 2016
Inflammatory response plays an important role in the activation and progress of many debilitating diseases. Natural products, like cannabidiol, a constituent of Cannabis sativa, and moringin, an isothiocyanate obtained from myrosinase-mediated hydrolysis
Iori, Renato, Grassi, Gianpaolo, Giacoppo, Sabrina, Mazzon, Emanuela, Rajan, Thangavelu Soundara, De Nicola, Gina Rosalinda, POLLASTRO, Federica, Bramanti, Placido   +7 more
core   +4 more sources

Anatomical and Chemical Analysis of Moringa oleifera Stem Tissue Grown under Controlled Conditions

Horticulturae, 2023
Moringa oleifera is a relatively well-studied ethnobotanical species, but information is limited regarding its stem anatomy and the production potential of phytochemicals from bark tissue.
Holly M. McVea, Lisa J. Wood
doaj   +2 more sources

The Potential of Glucosinolates and Their Hydrolysis Products as Inhibitors of Cytokine Storms [PDF]

Molecules
A cytokine storm is an intense inflammatory response characterized by the overproduction of proinflammatory cytokines, resulting in tissue damage, and organ dysfunction. Cytokines play a crucial role in various conditions, such as coronavirus disease, in
Kingsley Ochar, Kanivalan Iwar, Vadakkemuriyil Divya Nair, Yun-Jo Chung, Bo-Keun Ha, Seong-Hoon Kim   +5 more
doaj   +2 more sources

Antioxidant, anticancer, and anti-inflammatory potential of Moringa seed and Moringa seed oil: A comprehensive approach. [PDF]

Food Sci Nutr
This article provides a comprehensive summary of the noteworthy discoveries derived from a rigorous investigation that explored into the impact of moringa seeds on the prevention/reduction of various cancers and other complex diseases. Abstract Moringa oleifera, a widely recognized plant more commonly known as moringa, has obtained significant research
Shahbaz M, Naeem H, Batool M, Imran M, Hussain M, Mujtaba A, Alsagaby SA, Al Abdulmonem W, El-Ghorab AH, Ghoneim MM, Shaker ME, Abdelgawad MA, Al Jbawi E.   +12 more
europepmc   +2 more sources

Moringin activates Wnt canonical pathway by inhibiting GSK3β in a mouse model of experimental autoimmune encephalomyelitis

Drug Design, Development and Therapy, 2016
Sabrina Giacoppo,1 Thangavelu Soundara Rajan,1 Gina Rosalinda De Nicola,2 Renato Iori,2 Placido Bramanti,1 Emanuela Mazzon1 1IRCCS Centre Neurolesi “Bonino-Pulejo”, Messina, Italy; 2Council for Agricultural Research and Economics, Research ...
Giacoppo S, Soundara Rajan T, De Nicola GR, Iori R, Bramanti P, Mazzon E   +5 more
doaj   +1 more source

Topical moringin cream relieves neuropathic pain by suppression of inflammatory pathway and voltage-gated ion channels in murine model of multiple sclerosis [PDF]

Molecular Pain, 2017
Background Neuropathic pain represents the major public health burden with a strong impact on quality life in multiple sclerosis patients. Although some advances have been obtained in the last years, the conventional therapies remain poorly effective ...
Sabrina Giacoppo, Renato Iori, Placido Bramanti, Emanuela Mazzon   +3 more
doaj   +4 more sources