Results 11 to 20 of about 558 (127)

Antiallergic Effect of the Alpha-Cyclodextrin Moringin Complex in Rat Basophilic Leukaemia (RBL-2H3) Cell Line [PDF]

Advances in Pharmacological and Pharmaceutical Sciences
Allergic diseases (ADs) are a major concern when it comes to public well-being. Moringa oleifera Lam is a tropical plant that is used in traditional medicine due to the presence of isothiocyanate.
Ebtisam Yousef A. Alnakeeb, Ahmad Faizal Abdull Razis, Kim Wei Chan, Chau Ling Tham, Yee Han Chan, Anwar Salm Kalifa Kafo, Nuzul Noorahya Jambari, Patrick Rollin, Florence Djedaini-Pilard   +8 more
doaj   +5 more sources

Human gingival mesenchymal stem cells pretreated with vesicular moringin nanostructures as a new therapeutic approach in a mouse model of spinal cord injury [PDF]

Journal of Tissue Engineering and Regenerative Medicine, 2019
Spinal cord injury (SCI) is a neurological disorder that arises from a primary acute mechanical lesion, followed by a pathophysiological cascade of events that leads to further spinal cord tissue damage.
Santa Mammana, Agnese Gugliandolo, Francesca Diomede   +2 more
exaly   +8 more sources

Transcriptomic Analysis of Stem Cells Treated with Moringin or Cannabidiol: Analogies and Differences in Inflammation Pathways [PDF]

International Journal of Molecular Sciences, 2019
Inflammation is a common feature of many neurodegenerative diseases. The treatment of stem cells as a therapeutic approach to repair damage in the central nervous system represents a valid alternative. In this study, using Next-Generation Sequencing (NGS)
Luigi Chiricosta, Serena Silvestro, Jacopo Pizzicannella   +2 more
exaly   +7 more sources

The α-Cyclodextrin/Moringin Complex: A New Promising Antimicrobial Agent against Staphylococcus aureus [PDF]

Molecules, 2018
Antimicrobial resistance is one of the major clinical concerns, making the discovery of new antimicrobial drugs desirable. Moringin (MOR), the major isothiocyanate produced from Moringa oleifera seeds, could represent an alternative therapeutic strategy ...
Letizia Romeo, Renato Iori, Patrick Rollin   +2 more
exaly   +5 more sources

Supramolecular Engineering of Nanoceria for Management and Amelioration of Age‐Related Macular Degeneration via the Two‐Level Blocking of Oxidative Stress and Inflammation [PDF]

Advanced Science
Age‐related macular degeneration (AMD), characterized by choroidal neovascularization (CNV), is the global leading cause of irreversible blindness.
Mingyu Xu, Yifan Zhou, Yufeng Xu, An Shao, Haijie Han, Juan Ye   +5 more
doaj   +3 more sources

A Combined Approach of NMR and Mass Spectrometry Techniques Applied to the α-Cyclodextrin/Moringin Complex for a Novel Bioactive Formulation † [PDF]

Molecules, 2018
Moringin, obtained via enzymatic conversion of the glucosinolate precursor glucomoringin, is an uncommon member of the isothiocyanate class, and has been proven to possess a broad range of biological activities such as antitumor activity, protection ...
David Mathiron, Renato Iori, Serge Pilard   +2 more
exaly   +5 more sources

The Chemopreventive Phytochemical Moringin Isolated from Moringa oleifera Seeds Inhibits JAK/STAT Signaling. [PDF]

PLoS ONE, 2016
Sulforaphane (SFN) and moringin (GMG-ITC) are edible isothiocyanates present as glucosinolate precursors in cruciferous vegetables and in the plant Moringa oleifera respectively, and recognized for their chemopreventive and medicinal properties.
Carina Michl, Fabio Vivarelli, Julia Weigl, Gina Rosalinda De Nicola, Donatella Canistro, Moreno Paolini, Renato Iori, Anne Rascle   +7 more
doaj   +5 more sources

Methodology for rapid isolation of Moringin: Potential anticancer compound from the seeds of Moringa stenopetala [PDF]

Pharmaceutica Analytica Acta, 2017
The seeds of Moringa stenopetala which are known to be rich sources of glucosinolates, primarily glucomoringin, have been shown to have limited anticancer effects when tested in vitro.
Habtemariam, Solomon
core   +3 more sources

α-Cyclodextrin/Moringin Impacts Actin Cytoskeleton Dynamics with Potential Implications for Synaptic Organization: A Preliminary Transcriptomic Study in NSC-34 Motor Neurons [PDF]

International Journal of Molecular Sciences
α-Cyclodextrin/Moringin (α-CD/MOR) is an isothiocyanate showing neuroprotective and antioxidant properties. In this work, we studied in differentiated NSC-34 motor neurons cell line the molecular pathways activated following a treatment of 96 h with α-CD/MOR at different doses, namely 0.5, 5 and 10 μM.
Agnese Gugliandolo, Luigi Chiricosta, Gabriella Cali   +2 more
exaly   +3 more sources

The Potential of Glucosinolates and Their Hydrolysis Products as Inhibitors of Cytokine Storms [PDF]

Molecules
A cytokine storm is an intense inflammatory response characterized by the overproduction of proinflammatory cytokines, resulting in tissue damage, and organ dysfunction. Cytokines play a crucial role in various conditions, such as coronavirus disease, in
Kingsley Ochar, Kanivalan Iwar, Vadakkemuriyil Divya Nair, Yun-Jo Chung, Bo-Keun Ha, Seong-Hoon Kim   +5 more
doaj   +2 more sources