Moringin, A Stable Isothiocyanate from Moringa oleifera, Activates the Somatosensory and Pain Receptor TRPA1 Channel In Vitro [PDF]
Molecules, 2020 Moringa oleifera Lam. is a tropical plant widely used in traditional medicines and as a food supplement. It is characterized by the presence of glucosinolates and isothiocyanates; the stable isothiocyanate 4-[(α-l-rhamnosyloxy)benzyl]isothiocyanate (
Gigliola Borgonovo +7 more
doaj +7 more sources
Molecules, 2019 Moringin [4-(α-L-rhamnosyloxy) benzyl isothiocyanate] is an isothiocyanate extracted from Moringa oleifera seeds. It is an antioxidant known for several biological properties useful in the treatment of neurodegenerative diseases.
Francesca Diomede +2 more
exaly +7 more sources
A Combined Approach of NMR and Mass Spectrometry Techniques Applied to the α-Cyclodextrin/Moringin Complex for a Novel Bioactive Formulation † [PDF]
Molecules, 2018 Moringin, obtained via enzymatic conversion of the glucosinolate precursor glucomoringin, is an uncommon member of the isothiocyanate class, and has been proven to possess a broad range of biological activities such as antitumor activity, protection ...
David Mathiron +2 more
exaly +6 more sources
The α-Cyclodextrin/Moringin Complex: A New Promising Antimicrobial Agent against Staphylococcus aureus [PDF]
Molecules, 2018 Antimicrobial resistance is one of the major clinical concerns, making the discovery of new antimicrobial drugs desirable. Moringin (MOR), the major isothiocyanate produced from Moringa oleifera seeds, could represent an alternative therapeutic strategy ...
Patrick Rollin +2 more
exaly +6 more sources
The Moringin/α-CD Pretreatment Induces Neuroprotection in an In Vitro Model of Alzheimer’s Disease: A Transcriptomic Study [PDF]
Current Issues in Molecular Biology, 2021 Alzheimer’s disease (AD) is a progressive neurodegenerative disorder and represents the most common form of senile dementia. Autophagy and mitophagy are cellular processes that play a key role in the aggregation of β-amyloid (Aβ) and tau phosphorylation.
Patrick Rollin +2 more
exaly +9 more sources
Human gingival mesenchymal stem cells pretreated with vesicular moringin nanostructures as a new therapeutic approach in a mouse model of spinal cord injury [PDF]
Journal of Tissue Engineering and Regenerative Medicine, 2019 Abstract Spinal cord injury (SCI) is a neurological disorder that arises from a primary acute mechanical lesion, followed by a pathophysiological cascade of events that leads to further spinal cord tissue damage. Several preclinical and clinical studies have highlighted the ability of stem cell therapy to improve long‐term functional recovery in SCI ...
Romina Zappacosta +2 more
exaly +7 more sources
The Chemopreventive Phytochemical Moringin Isolated from Moringa oleifera Seeds Inhibits JAK/STAT Signaling. [PDF]
PLoS ONE, 2016 Sulforaphane (SFN) and moringin (GMG-ITC) are edible isothiocyanates present as glucosinolate precursors in cruciferous vegetables and in the plant Moringa oleifera respectively, and recognized for their chemopreventive and medicinal properties.
Carina Michl +7 more
doaj +8 more sources
Aqueous extracts of Moringa oleifera and Cinnamomum cassia as promising sources of antibiofilm compounds against mucoid and small colony variants of Pseudomonas aeruginosa and Staphylococcus aureus [PDF]
BiofilmBacterial biofilms formed by Staphylococcus aureus and Pseudomonas aeruginosa pose significant challenges in treating cystic fibrosis (CF) airway infections due to their resistance to antibiotics.
Eduarda Silva +5 more
doaj +4 more sources
Methodology for rapid isolation of Moringin: Potential anticancer compound from the seeds of Moringa stenopetala [PDF]
Pharmaceutica Analytica Acta, 2017 The seeds of Moringa stenopetala which are known to be rich sources of glucosinolates, primarily glucomoringin, have been shown to have limited anticancer effects when tested in vitro.
Solomon Habtemariam +1 more
core +3 more sources
Drug Design, Development and Therapy, 2016 Aberrant canonical Wnt-beta-catenin signaling has been reported in multiple sclerosis (MS), although the results are controversial. The present study aimed to examine the role of the Wnt-beta-catenin pathway in experimental MS and also to test moringin ...
Soundara Rajan, Thangavelu +5 more
core +6 more sources