Results 1 to 10 of about 253,014 (255)

Attenuation by dextromethorphan on the higher liability to morphine-induced reward, caused by prenatal exposure of morphine in rat offspring [PDF]

open access: yesJournal of Biomedical Science, 2009
Co-administration of dextromethorphan (DM) with morphine during pregnancy and throughout lactation has been found to reduce morphine physical dependence and tolerance in rat offspring.
Tao Pao-Luh   +3 more
doaj   +4 more sources

Intrathecal morphine plus general anesthesia in cardiac surgery: effects on pulmonary function, postoperative analgesia, and plasma morphine concentration [PDF]

open access: yesClinics, 2009
OBJECTIVES: To evaluate the effects of intrathecal morphine on pulmonary function, analgesia, and morphine plasma concentrations after cardiac surgery. INTRODUCTION: Lung dysfunction increases morbidity and mortality after cardiac surgery.
Luciana Moraes dos Santos   +4 more
doaj   +6 more sources

MORPHINE [PDF]

open access: bronzeAnesthesiology, 1959
G. M. Smith, H. K. Beecher
openalex   +2 more sources

Pharmacogenomics and Morphine [PDF]

open access: yesThe Journal of Clinical Pharmacology, 2021
AbstractMorphine is an opioid analgesic indicated in the treatment of acute and chronic moderate to severe pain. From a pharmacodynamic standpoint, morphine exerts its effects by agonizing mu‐opioid receptors predominantly, resulting in analgesia and sedation.
Adaku Ofoegbu, Earl B. Ettienne
openaire   +3 more sources

Modulation of Morphine Analgesia, Antinociceptive Tolerance, and Mu-Opioid Receptor Binding by the Cannabinoid CB2 Receptor Agonist O-1966

open access: yesFrontiers in Pharmacology, 2022
Acutely, non-selective cannabinoid (CB) agonists have been shown to increase morphine antinociceptive effects, and we and others have also demonstrated that non-selective CB agonists attenuate morphine antinociceptive tolerance. Activation of cannabinoid
Zachary W. Reichenbach   +10 more
doaj   +1 more source

Suppressing high mobility group box-1 release alleviates morphine tolerance via the adenosine 5’-monophosphate-activated protein kinase/heme oxygenase-1 pathway

open access: yesNeural Regeneration Research, 2023
Opioids, such as morphine, are the most potent drugs used to treat pain. Long-term use results in high tolerance to morphine. High mobility group box-1 (HMGB1) has been shown to participate in neuropathic or inflammatory pain, but its role in morphine ...
Tong-Tong Lin   +12 more
doaj   +1 more source

Morphine Nitrate and Morphine Acetate**Scientific Section at Detroit. [PDF]

open access: yesThe Journal of the American Pharmaceutical Association (1912), 1915
n ...
Engelhardt, H., Winters, O. E.
openaire   +3 more sources

Differential Changes in Expression of Stress- and Metabolic-related Neuropeptides in the Rat Hypothalamus during Morphine Dependence and Withdrawal [PDF]

open access: yes, 2013
Chronic morphine treatment and naloxone precipitated morphine withdrawal activates stress-related brain circuit and results in significant changes in food intake, body weight gain and energy metabolism.
Ferenczi, Szilamér   +6 more
core   +5 more sources

Home - About - Disclaimer - Privacy