Results 1 to 10 of about 135,473 (192)
Pharmacogenomics and Morphine [PDF]
AbstractMorphine is an opioid analgesic indicated in the treatment of acute and chronic moderate to severe pain. From a pharmacodynamic standpoint, morphine exerts its effects by agonizing mu‐opioid receptors predominantly, resulting in analgesia and sedation.
Adaku Ofoegbu, Earl B. Ettienne
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Acutely, non-selective cannabinoid (CB) agonists have been shown to increase morphine antinociceptive effects, and we and others have also demonstrated that non-selective CB agonists attenuate morphine antinociceptive tolerance. Activation of cannabinoid
Zachary W. Reichenbach+10 more
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THE TREATMENT OF MORPHINISM. [PDF]
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Sainsbury, Harrington, Jennings, Oscar
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Opioids, such as morphine, are the most potent drugs used to treat pain. Long-term use results in high tolerance to morphine. High mobility group box-1 (HMGB1) has been shown to participate in neuropathic or inflammatory pain, but its role in morphine ...
Tong-Tong Lin+12 more
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Morphine Nitrate and Morphine Acetate**Scientific Section at Detroit. [PDF]
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Engelhardt, H., Winters, O. E.
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Perineuronal morphine: a comparison with epidural morphine [PDF]
SummaryIn a double‐blind, randomised controlled cross‐over study the effects of perineuronal (perifemoral) injections of morphine were compared with epidural injections with the same amount of morphine in patients after knee surgery. Better pain scores were achieved during treatment with epidural morphine.
H.V. Johannsen+4 more
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Neural mechanisms underlying morphine withdrawal in addicted patients: a review [PDF]
Morphine is one of the most potent alkaloid in opium, which has substantial medical uses and needs and it is the first active principle purified from herbal source. Morphine has commonly been used for relief of moderate to severe pain as it acts directly
Nima Babhadiashar+5 more
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Intravenous (i.v.) morphine is a safe, robust, and recommended treatment for severe pain using the titration principle. Despite its high efficacy, it is impacted by organizational constraints related to venous access.
Thomas Duflot+6 more
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