Pharmacogenomics and Morphine [PDF]
The Journal of Clinical Pharmacology, 2021 AbstractMorphine is an opioid analgesic indicated in the treatment of acute and chronic moderate to severe pain. From a pharmacodynamic standpoint, morphine exerts its effects by agonizing mu‐opioid receptors predominantly, resulting in analgesia and sedation.
Adaku Ofoegbu, Earl B. Ettienne
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THE TREATMENT OF MORPHINISM. [PDF]
The Lancet, 1909 n ...
Sainsbury, Harrington, Jennings, Oscar
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Morphine Nitrate and Morphine Acetate**Scientific Section at Detroit. [PDF]
The Journal of the American Pharmaceutical Association (1912), 1915 n ...
Engelhardt, H., Winters, O. E.
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Perineuronal morphine: a comparison with epidural morphine [PDF]
Anaesthesia, 1988 SummaryIn a double‐blind, randomised controlled cross‐over study the effects of perineuronal (perifemoral) injections of morphine were compared with epidural injections with the same amount of morphine in patients after knee surgery. Better pain scores were achieved during treatment with epidural morphine.
H.V. Johannsen +4 more
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Differential Changes in Expression of Stress- and Metabolic-related Neuropeptides in the Rat Hypothalamus during Morphine Dependence and Withdrawal [PDF]
, 2013 Chronic morphine treatment and naloxone precipitated morphine withdrawal activates stress-related brain circuit and results in significant changes in food intake, body weight gain and energy metabolism.
Ferenczi, Szilamér +6 more
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A randomised, controlled, double blind, non-inferiority trial of ultrasound-guided fascia iliaca block vs. spinal morphine for analgesia after primary hip arthroplasty [PDF]
, 2016 We performed a single centre, double blind, randomised, controlled, non-inferiority study comparing ultrasound-guided fascia iliaca block with spinal morphine for the primary outcome of 24-h postoperative morphine consumption in patients undergoing ...
Anderson, K. +7 more
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Effects of low dose morphine on perceived sleep quality in patients with refractory breathlessness : a hypothesis generating study [PDF]
, 2015 © 2015 Asian Pacific Society of Respirology. Background and objective The management of chronic refractory breathlessness is one of the indications for regular low-dose (≤30 mg/24 h) oral sustained release morphine.
Abernethy, Amy P. +6 more
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Ethanol reversal of tolerance to the respiratory depressant effects of morphine [PDF]
, 2015 Opioids are the most common drugs associated with unintentional drug overdose. Death results from respiratory depression. Prolonged use of opioids results in the development of tolerance but the degree of tolerance is thought to vary between different ...
A Fugelstad +62 more
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Preventing effect of vitamin E on oocytes apoptosis in morphinetreated mice [PDF]
, 2013 Several studies have shown that Morphine Sulfate affects on fertility, embryogenesis and consequent pregnancy loss and ultrastructural alterations of oocytes in animal model.
Asadi, E. +3 more
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Postmortem tissue distribution of morphine and its metabolites in a series of heroin related deaths [PDF]
, 2018 The abuse of heroin (diamorphine) and heroin deaths are growing around the world. The interpretation of the toxicological results from suspected heroin deaths is notoriously difficult especially in cases where there may be limited samples.
Beer, Lewis J. +6 more
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