Results 21 to 30 of about 161,700 (313)

The Effect of Acute and Chronic Morphine on Some Blood Biochemical ‎Parameters in an Inflammatory Condition in Gonadectomized Male Rats [PDF]

Addiction and Health, 2015
Background: Opiates affect blood factors as well as pain and inflammation in a gender-dependent manner. The aim of the present study was to evaluate the effects of morphine on serum glucose, cholesterol, triglycerides, and urea in gonadectomized and ...
Mohadeseh Chahkandi, Nayerreh Askari, Gholamreza Asadikaram   +2 more
doaj  

The effectiveness of Patient Controlled Analgesia (PCA) morphine-ketamine compared to Patient Controlled Analgesia (PCA) morphine to reduce total dose of morphine and Visual Analog Scale (VAS) in postoperative laparotomy surgery

Bali Journal of Anesthesiology, 2017
Background: Laparotomy may cause moderate to severe after surgery pain, thus adequate pain management is needed. The addition of ketamine in patient controlled analgesia (PCA) morphine after surgery can be the option.
I Gusti Ngurah Mahaalit Aribawa, Tjokorda Gde Agung Senapathi, Made Wiryana, I Ketut Sinardja, I Gede Budiarta, I Made Gede Widnyana, I Wayan Aryabiantara, Pontisomaya Parami, Pande Nyoman Kurniasari, Adinda Putra Pradhana   +9 more
doaj   +1 more source

Effect of human mesenchymal stem cell secretome administration on morphine self-administration and relapse in two animal models of opioid dependence

Translational Psychiatry, 2022
The present study investigates the possible therapeutic effects of human mesenchymal stem cell-derived secretome on morphine dependence and relapse. This was studied in a new model of chronic voluntary morphine intake in Wistar rats which shows classic ...
María Elena Quintanilla, Mauricio Quezada, Paola Morales, Pablo Berríos-Cárcamo, Daniela Santapau, Marcelo Ezquer, Mario Herrera-Marschitz, Yedy Israel, Fernando Ezquer   +8 more
doaj   +1 more source

Context-dependent effects of the CB1 receptor antagonist rimonabant on morphine-induced behavioral sensitization in female mice

Frontiers in Pharmacology, 2023
Introduction: The endocannabinoid system has been implicated in the neurobiology of opioid use disorder. While the CB1 receptor antagonist rimonabant has been shown to block some of the behavioral effects of opioids, studies suggest that the treatment ...
Eduardo A. V. Marinho, Eduardo A. V. Marinho, Alexandre Justo Oliveira-Lima, Alexandre Justo Oliveira-Lima, Henrique S. Reis, Renan Santos-Baldaia, Raphael Wuo-Silva, Andre W. Hollais, Thais S. Yokoyama, Roberto Frussa-Filho, Lais F. Berro, Lais F. Berro, Lais F. Berro   +12 more
doaj   +1 more source

Differential Changes in Expression of Stress- and Metabolic-related Neuropeptides in the Rat Hypothalamus during Morphine Dependence and Withdrawal

, 2013
Chronic morphine treatment and naloxone precipitated morphine withdrawal activates stress-related brain circuit and results in significant changes in food intake, body weight gain and energy metabolism.
Nunez, Cristina, Edina Zelei, M Victoria Milanés, Polyák, Ágnes, Zelei, Edina, Agnes Polyák, Krisztina J Kovács, Kovács, Krisztina J., Cristina Núnez, Milanes, Victoria M., Pintér-Kübler, Bernadett, Ferenczi, Szilamér, Bernadett Pintér-Kübler, Szilamér Ferenczi   +13 more
core   +1 more source

Morphine pre-exposure facilitates reinstatement but attenuates retention of morphine-induced place preference [PDF]

, 2010
BACKGROUND: Drug-associated conditioned stimuli are a key factor to induce morphine relapse. To date, limited evidence is available regarding the impact of drug history on propensity or vulnerability to relapse after long-term abstinence.
Yang, Xiaoyan, Sui, Nan, Zheng, Xigeng, Wang, Dongmei, Li, Yonghui   +4 more
core   +1 more source

Synthesis of (−)-Morphine

, 2016
The preparation of the diastereomerically pure β-tetralone ketal 4 is reported. Intramolecular alkylidene C−H insertion followed by hydrolysis of 4 proceeded to give the enantiomerically pure cyclopentene 15.
Arnold L. Rheingold (1274736), Douglass F. Taber (1568878), Timothy D. Neubert (1600189)   +2 more
core   +2 more sources

Resveratrol reverses morphine-induced neuroinflammation in morphine-tolerant rats by reversal HDAC1 expression

Journal of the Formosan Medical Association, 2016
We previously showed that subsequent intrathecal (i.t.) injection of resveratrol (30 μg) significantly reverses morphine-evoked neuroinflammation in morphine-tolerant rats. The present study examined the underlying mechanism.
Ru-Yin Tsai, Juei-Chii Wang, Kuang-Yi Chou, Chih-Shung Wong, Chen-Hwan Cherng   +4 more
doaj   +1 more source

THE TREATMENT OF MORPHINISM. [PDF]

The Lancet, 1909
n ...
Sainsbury, Harrington, Jennings, Oscar
openaire   +4 more sources

Significance of Metabolite Ratios in the Interpretation of Segmental Hair Testing Results—Differentiation of Single from Chronic Morphine Use in a Case Series

Metabolites, 2021
In morphine intoxication cases, forensic toxicologists are frequently confronted with the question of if the individual was opioid-tolerant or opioid-naïve, which can be investigated by hair analysis. However, interpretation of results can be challenging.
Milena M. Madry, Sandra N. Poetzsch, Andrea E. Steuer, Thomas Kraemer, Markus R. Baumgartner   +4 more
doaj   +1 more source