Results 41 to 50 of about 162,133 (313)

Effets d'un traitement chronique par la morphine sur le protéome des cellules de neuroblastome humain SH-SY5Y [PDF]

open access: yes, 2007
Afin de mieux comprendre les adaptations cellulaires induites suite à une prise chronique de morphine, une stratégie de type protéomique différentielle combinant les techniques d'électrophorèse et de spectrométrie de masse a été entreprise dans des ...
Mouledous, Lionel
core  

Postsurgical Opioid Prescribing Among Injured Workers in Washington State: 2017–2020 Trends and Policy Effects

open access: yesAmerican Journal of Industrial Medicine, EarlyView.
ABSTRACT Introduction The widespread adoption of longer duration opioid prescribing for acute pain management following surgeries has coincided with concerning increases in misuse, dependence, and overdose. We evaluated the impact of voluntary opioid prescribing guidelines and concurrent state pharmacy rules on prescribing trends following surgeries ...
John R. Haight   +4 more
wiley   +1 more source

Perioperative Intravenous Dexamethasone Improves Pain and Functional Outcomes After Arthroscopic Rotator Cuff Repair

open access: yesArthroscopy, Sports Medicine, and Rehabilitation, EarlyView.
Purpose To evaluate the effect of perioperative dexamethasone on patient‐reported pain, functional outcomes, and minimal clinically important difference (MCID) achievement following arthroscopic rotator cuff repair. Methods Patients who underwent rotator cuff repair between 2013 and 2023 were identified and divided into groups.
Trevor D. Wolterink   +9 more
wiley   +1 more source

Application of Morphine Anesthesia for Oral Surgery [PDF]

open access: yes, 2004
P(論文)Morphine anesthesia is often applied for the cardiovascular surgery and to patients complicated with cardiovascular disease because it has a property of hemodynamic stability due to the block from nociceptive stimulation and pain. However, there are
8772   +41 more
core   +1 more source

Acute and chronic effects of morphine on Low-Mg2+ ACSF-induced epileptiform activity during infancy in mice hippocampal slices

open access: yesResearch in Pharmaceutical Sciences, 2019
Interaction of morphine and seizure is complex. Mouse brain hippocampal slices were used to estimate how acute and chronic morphine treatment alters the low-magnesium artificial cerebrospinal fluid (LM-ACSF)-induced seizure activity.
Yousef Panahi   +6 more
doaj   +1 more source

Dysregulation of Vesicular Glutamate Transporter VGluT2 via BDNF/TrkB Pathway Contributes to Morphine Tolerance in Mice

open access: yesFrontiers in Pharmacology, 2022
Morphine is widely used in the treatment of moderate to severe pain. Long-term use of morphine leads to various adverse effects, such as tolerance and hyperalgesia.
Liqiong He   +12 more
doaj   +1 more source

Beyond the label: Rethinking off‐label drug use in paediatrics. Towards a scientifically grounded and safer future for paediatric pharmacotherapy

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Despite regulatory progress being made in the past two decades, off‐label drug use in paediatrics remains pervasive, with prevalence estimated between 3% and 97% of prescriptions across different clinical settings. Off‐label use—defined as prescribing outside the conditions described in the Summary of Product Characteristics (SmPC)—is often ...
Tjitske M. van der Zanden   +3 more
wiley   +1 more source

An evaluation of palliative care in rural Tanzania where availability of oral morphine is intermittent or absent [PDF]

open access: yes, 2011
Includes bibliographical details.In Tanzania, palliative care is relatively new, and faces the common challenges of access to services, crucial medications, and education.
Hartwig, Kristopher
core  

The effect of cannabinoid type 2 receptor agonist on morphine tolerance

open access: yesIBRO Neuroscience Reports
Pain highly impacts the quality of life of patients. Morphine is used for pain treatment; however, its side effects, especially morphine tolerance, limit its use in the clinic. The problem of morphine tolerance has plagued health workers and patients for
Di Cui, Yuanyuan Zhang, Mingyue Zhang
doaj   +1 more source

Morphine Binds Creatine Kinase B and Inhibits Its Activity

open access: yesFrontiers in Cellular Neuroscience, 2018
Morphine is an analgesic alkaloid used to relieve severe pain, and irreversible binding of morphine to specific unknown proteins has been previously observed.
Ivan Weinsanto   +13 more
doaj   +1 more source

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