Results 51 to 60 of about 176,329 (291)
The effect of cannabinoid type 2 receptor agonist on morphine tolerance
IBRO Neuroscience ReportsPain highly impacts the quality of life of patients. Morphine is used for pain treatment; however, its side effects, especially morphine tolerance, limit its use in the clinic. The problem of morphine tolerance has plagued health workers and patients for
Di Cui, Yuanyuan Zhang, Mingyue Zhang
doaj +1 more source
Morphine-induced taste aversions : A consideration of parameters
, 1978 Following consumption of saccharin, groups of rats were injected with various doses of morphine sulfate. Although no aversion was found after one conditioning trial, repeated saccharin-morphine pairings resulted in decreases in consumption of the ...
W.J. Jacobs (16783884) +2 more
core +1 more source
Basic and Clinical Neuroscience, 2011 Effects of intra-central amygdala administration of L-arginine, a nitric oxide precursor, and NG-nitro-L-arginine methyl-ester (L NAME), a nitric oxide synthase inhibitor, on the morphine-induced sensitization and also on the expression of morphine ...
Hedayat Sahraei +7 more
doaj +2 more sources
Journal of Pharmacy and Pharmacology, 1957 Abstract A series of compounds which antagonise the depressant activity of morphine in dogs is described. The most active compounds are the previously described 2:4-diamino-5-phenylthiazole and tetrahydro-5-aminoacridine. A mixture of both substances is more active than either alone.
F H, SHAW, S, GERSHON, G A, BENTLEY
openaire +2 more sources
Arthroscopy, Sports Medicine, and Rehabilitation, EarlyView.Purpose To identify risk factors that predict the need for rescue opioid use and patient‐reported outcomes following an opioid‐limiting postoperative analgesia protocol after anterior cruciate ligament reconstruction. Methods This prospective cohort study recruited 44 patients undergoing primary arthroscopic‐assisted anterior cruciate ligament ...
Eric V. Neufeld +6 more
wiley +1 more source
فصلنامه دانشگاه علوم پزشکی جهرم, 2013 The most important side effect of addictive drugs is their interaction with nervous system so that soon after taking the drug, the neurons̉ connections in nervous system are addicted to receiving the drugs frequently. The aim of this study was the effect
Eebrahim Hosseini +4 more
doaj
A Nine-Step Formal Synthesis of (±)-Morphine
, 2019 A nine-step stereoselective formal synthesis of (±)-morphine from readily available o-vanillin is presented. The carbocyclic structure of morphine was quickly assembled through an orchestration of the intermolecular Diels–Alder/Claisen/Friedel–Crafts ...
Louis Barriault +5 more
core +1 more source
British Journal of Clinical Pharmacology, EarlyView.Abstract Despite regulatory progress being made in the past two decades, off‐label drug use in paediatrics remains pervasive, with prevalence estimated between 3% and 97% of prescriptions across different clinical settings. Off‐label use—defined as prescribing outside the conditions described in the Summary of Product Characteristics (SmPC)—is often ...
Tjitske M. van der Zanden +3 more
wiley +1 more source
, 2023 Amany F Omara,1 Hadal Hassan Mohsen,2 Alaa Mohammed Abo Hagar,1 Ahmed F Abdelrahman1 1Department of Anaesthesia and Surgical Intensive Care, Faculty of Medicine, Tanta University, Tanta, Egypt; 2Department of Anaesthesia and Surgical Intensive Care ...
Mohammed Abo Hagar A +3 more
core
Precision medicine in paediatrics: Progress and priorities
British Journal of Clinical Pharmacology, EarlyView.Precision medicine is revolutionizing personalized healthcare, advancing both diagnostics and therapeutics at an unprecedented pace. Reviewing the paediatric applications of pharmacometrics, pharmacogenomics and advanced therapy medicinal products highlights not only the relevance of these exciting innovations to frontline care but also the significant
Nicola Husain +3 more
wiley +1 more source