Results 71 to 80 of about 161,700 (313)

The gamma-aminobutyric acid type B (GABA_B) receptor agonist baclofen inhibits morphine sensitization by decreasing the dopamine level in rat nucleus accumbens

Behavioral and Brain Functions, 2012
Background Repeated morphine exposure can induce behavioral sensitization. There are evidences have shown that central gamma-aminobutyric acid (GABA) system is involved in morphine dependence.
Fu Zhenyu, Yang Hongfa, Xiao Yuqiang, Zhao Gang, Huang Haiyan   +4 more
doaj   +1 more source

Antibiotic-Driven Gut Microbiome Disorder Alters the Effects of Sinomenine on Morphine-Dependent Zebrafish

Frontiers in Microbiology, 2020
Morphine is one of the most severely abused drugs in the world. Previous research on morphine addiction has focused on the central nervous system (CNS). Studies have shown that a two-way regulation of the brain and gut microbiota (GM), suggesting a link ...
Zhu Chen, Chen Zhijie, Zhou Yuting, Xiao Shilin, Zhou Qichun, Ou Jinying, Luo Chaohua, Li Jing, Mo Zhixian   +8 more
doaj   +1 more source

Exploring Cerumen as an Alternative Matrix for Drug Detection and Quantification: Method Development and Application in Clinical Samples

Drug Testing and Analysis, EarlyView.
An LC–MS/MS method was developed for the detection of 33 psychoactive medications in cerumen (earwax) and applied to the samples of 60 psychiatric inpatient volunteers. The findings highlighted the utility of cerumen as an innovative biospecimen in clinical toxicological analysis.
Dimitrios Phaedon Kevrekidis, Helen G. Gika, Georgios Panagiotoglou, Eleni Parlapani, Pavlos Pavlidis, Nikolaos Raikos   +5 more
wiley   +1 more source

Evaluation of the Drug–Drug Interaction Potential of Cannabidiol Against UGT2B7-Mediated Morphine Metabolism Using Physiologically Based Pharmacokinetic Modeling

Pharmaceutics
Background: Morphine is a commonly prescribed opioid analgesic used to treat chronic pain. Morphine undergoes glucuronidation by UDP-glucuronosyltransferase (UGT) 2B7 to form morphine-3-glucuronide and morphine-6-glucuronide.
Shelby Coates, Keti Bardhi, Bhagwat Prasad, Philip Lazarus   +3 more
doaj   +1 more source

Laser neoureterocystostomy to treat ectopic ureters

Equine Veterinary Journal, EarlyView.
Abstract Background Ureteral ectopia is an uncommon but clinically important congenital abnormality in horses. If left untreated, it can lead to persistent dermatitis, urinary tract infections, and failure to thrive. Surgical correction is necessary, but traditional approaches have produced mixed results with high morbidity.
Caitlin Smith, Eric J. Parente
wiley   +1 more source

Application of Morphine Anesthesia for Oral Surgery

, 2004
P(論文)Morphine anesthesia is often applied for the cardiovascular surgery and to patients complicated with cardiovascular disease because it has a property of hemodynamic stability due to the block from nociceptive stimulation and pain. However, there are
8772, 8773, 中江, 次郎, 8770, 8771, ヤマザキ, シンヤ, 8776, KAWAAI, Hiroyoshi, カワアイ, ヒロヨシ, 8777, 川合, 宏仁, 8774, 8775, 大野, 敬, 金, 秀樹, 高田, 訓, YAMAZAKI, Shinya, KON, Hideki, コン, ヒデキ, 山崎, 信也, ナカエ, ジロウ, 8769, 8767, 8768, 8762, セイノ, ヒロアキ, 8781, 8782, 清野, 浩昭, 8765, 8766, オオノ, タカシ, 8763, 8764, OHNO, Takashi, TAKADA, Satoshi, 8780, 8778, NAKAE, Jiro, タカダ, サトシ, 8779, SEINO, Hiroaki   +41 more
core  

Next‐Generation Surgery: Integrating Artificial Intelligence, Genetic Technologies, Bioengineering and Rehabilitation Into Modern Practices

Exploration, EarlyView.
This graphic abstract depicts the convergence of artificial intelligence, genetic technologies, bioengineering, and rehabilitation as the core pillars of next‐generation surgery. These domains collectively enhance preoperative planning, intraoperative precision, tissue reconstruction, and postoperative recovery, driving a paradigm shift toward ...
Dengxiong Li, Jie Wang, Zhipeng Wang, Ruicheng Wu, Zhouting Tuo, Fanglin Shao, Wenjing Ge, Ziyu Shu, Yubo Yang, Dilinaer Wusiman, Qingxin Yu, Luxia Ye, Alisha Pati‐Alam, Facai Zhang, Koo Han Yoo, Susan Heavey, William C. Cho, Dechao Feng   +17 more
wiley   +1 more source

PKC-Mediated Potentiation of Morphine Analgesia by St. John’s Wort in Rodents and Humans

Journal of Pharmacological Sciences, 2014
Our purpose was to combine the use of morphine with clinically available inhibitors of protein kinase C (PKC), finally potentiating morphine analgesia in humans.
Nicoletta Galeotti, Mersedeh Farzad, Enrica Bianchi, Carla Ghelardini   +3 more
doaj   +1 more source

PSYCHOSIS OF MORPHINISM. [PDF]

JAMA: The Journal of the American Medical Association, 1905
All writers have mentioned the general defective conception of truth and the relation of right and wrong which appears to be a prominent symptom in all persons who use morphia. It is difficult to understand whether this is a veritable paralysis of the higher reasoning centers or a defect of the senses by which distorted conceptions of facts are not ...
openaire   +2 more sources

An evaluation of palliative care in rural Tanzania where availability of oral morphine is intermittent or absent

, 2011
Includes bibliographical details.In Tanzania, palliative care is relatively new, and faces the common challenges of access to services, crucial medications, and education.
Hartwig, Kristopher
core