Results 71 to 80 of about 176,329 (291)

Morphine Poisoning [PDF]

open access: yesThe Journal of Nervous and Mental Disease, 1919
n ...
openaire   +2 more sources

The effects of adding ketamine to morphine in patient-controlled intravenous analgesia after orthopedic surgeries [PDF]

open access: yes
Aim and Background: A routine method to control post-operative pain is patient-controlled intravenous analgesia (PCIA) using opioids. Regarding complications of opioids, it seems necessary to reduce their dosage and to improve the quality of analgesia ...
ایمانی, فرناد   +2 more
core  

Tramadol Co‐Administration with Oxycodone or Hydrocodone Increases Opioid Burden without Improving Postoperative Pain Control

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Tramadol is frequently co‐prescribed with oxycodone or hydrocodone after surgery under the assumption that its dual mechanism of action provides an opioid‐sparing benefit. However, evidence supporting this practice is limited and inconsistent. We conducted a secondary analysis of the multicenter IGNITE ADOPT‐PGx pragmatic trial of patients undergoing ...
Noor A. Nahid   +302 more
wiley   +1 more source

Evaluation of the Drug–Drug Interaction Potential of Cannabidiol Against UGT2B7-Mediated Morphine Metabolism Using Physiologically Based Pharmacokinetic Modeling

open access: yesPharmaceutics
Background: Morphine is a commonly prescribed opioid analgesic used to treat chronic pain. Morphine undergoes glucuronidation by UDP-glucuronosyltransferase (UGT) 2B7 to form morphine-3-glucuronide and morphine-6-glucuronide.
Shelby Coates   +3 more
doaj   +1 more source

Initiation of Gabapentin with Opioids and Risk of Respiratory Cardiovascular and Opioid‐Related Adverse Events Following Surgery for Breast Cancer

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Pain is a key determinant of quality‐of‐life following breast cancer surgery, the most common cancer operation in the United States. Gabapentinoids are frequently prescribed for pain management, yet their respiratory, cardiovascular, and opioid‐related adverse effects remain unclear.
Jyun‐Heng Lai   +12 more
wiley   +1 more source

Transcriptomic Profiling of SLC and ABC Transporters in the Human Term Placenta

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Solute carriers (SLC) and ATP‐binding cassette (ABC) transporters are essential for placental solute exchange and fetal protection, yet their transcriptomic profiles in the human placenta remain poorly characterized. Although fetal sex influences placental development and function, its impact on transporter expression is unclear.
Elijah Marsh Jung   +12 more
wiley   +1 more source

Characterization of a Single Chain Fv Antibody that Reacts with Free Morphine

open access: yesAntibodies, 2013
An immune phage library derived from mice, hyperimmunized with morphine-conjugated BSA, was used to isolate a single-chain Fv (scFv) clone, M86, with binding activity to morphine-conjugated thyroglobulin (morphine-C-Tg) but not to codeine-, cocaine-, or ...
Kazuhisa Sugimura   +6 more
doaj   +1 more source

Evaluation of interprofessional collaboration in a teaching session in patient partnership in pharmacy education

open access: yesThe Curriculum Journal, EarlyView.
Abstract Patient partnership in health education promotes collaborative and humanistic care. In pharmacy education, however, this approach remains uncommon. We aimed to co‐construct and assess a teaching session on pain management and dispensing refusal, involving patients as full partners. A participatory approach was used.
Marc‐Antoine Luc   +2 more
wiley   +1 more source

Opium trade and use during the Late Bronze Age: Organic residue analysis of ceramic vessels from the burials of Tel Yehud, Israel

open access: yesArchaeometry, EarlyView., 2022
Abstract Organic residue analysis was conducted on various vessels from burials at Tel Yehud, Israel. The analyses led to new reliable evidence for the presence of opioid alkaloids and their decomposition products. This research revitalizes a decades‐old discussion on the presence and function of the opium trade across a cultural region of utmost ...
Vanessa Linares   +5 more
wiley   +1 more source

Comparison of Patient-Controlled Analgesia Using Morphine With and Without Paracetamol in Postoperative Pain Control [PDF]

open access: yesPatient Safety and Quality Improvement Journal, 2016
Introduction: Postoperative pain control plays a pivotal role in reducing postoperative complications, hospitality time, and increasing satisfaction.
Mehryar Taghavi Gilani   +3 more
doaj  

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