Results 81 to 90 of about 176,329 (291)
Activation of Spinal Anti-analgesic System Following Electroacupuncture Stimulation in Rats
We evaluated the interaction between electroacupuncture (EA)-induced antinociception and an endogenous anti-analgesic system. EA was applied to the ST-36 acupoint for 45 min in male Sprague-Dawley rats, and pain thresholds were assessed by the hind-paw ...
Yohji Fukazawa +7 more
doaj +1 more source
A total of 2121 used syringes were analyzed in Athens, Thessaloniki, and Patras between 2022 and 2024. Distinct drug‐use patterns were observed across the three cities. Benzodiazepines, pregabalin, methadone, and fentanyl were increasingly detected in 2024.
Christina Matiaki +10 more
wiley +1 more source
Introduction: The GABAergic system of the brain plays a key role in morphine tolerance and sensitization. As isoniazid is a modulator of the GABAergic system, the present study aims to understand whether isoniazid can influence the induction of tolerance
Amir Abbas Barzegari, Kamran Shahabi
doaj
Effects of aqueous saffron extract (Crocus sativus L.) on the acquisition and reinstatement of morphine-induced conditioned place preference in mice [PDF]
Objective: In the present study, the effects of aqueous saffron extract (Crocus sativus L.) on the acquisition and reinstatement of morphine-induced conditioned place preference (CPP) in mice were investigated.
Hossein Hosseinzadeh +2 more
doaj
PKC-Mediated Potentiation of Morphine Analgesia by St. John’s Wort in Rodents and Humans
Our purpose was to combine the use of morphine with clinically available inhibitors of protein kinase C (PKC), finally potentiating morphine analgesia in humans.
Nicoletta Galeotti +3 more
doaj +1 more source
Enantioselective Synthesis of (−)-Codeine and (−)-Morphine
A new synthetic strategy for the synthesis of the opiate and amaryllidaceae alkaloids emerges employing a Pd-catalyzed asymmetric allylic alkylation to set the stereochemistry.
Barry M. Trost (1309395) +1 more
core +1 more source
ABSTRACT Methiodone (IC‐26) is a non‐fentanyl novel synthetic opioid which has recently been detected in drug seizures in Europe. There is still limited data about the drug in published toxicological case work, both in non‐fatal and fatal cases. We present a medicolegal autopsy case report on a fatal intoxication in an individual undergoing opioid ...
Lasse Pakanen +2 more
wiley +1 more source
Extended-release morphine sulfate in treatment of severe acute and chronic pain [PDF]
Robert J Balch, Andrea TrescotDepartment of Anesthesiology and Pain Medicine, University of Washington, Seattle, WA USAAbstract: Morphine is the archetypal opioid analgesic.
Robert J Balch, Andrea Trescot
core +1 more source
Fatalities within seven days after equine standing sedation: A prospective, multicentre study
Abstract Background Information regarding mortality associated with standing procedures in horses is sparse. Objectives To report data from >12,000 standing sedations. Study Design Confidential, observational, prospective, multicentre, cohort study.
Miguel Gozalo‐Marcilla +6 more
wiley +1 more source

