Results 101 to 110 of about 50,460 (257)
Microglia in morphine tolerance: cellular and molecular mechanisms and therapeutic potential
Frontiers in PharmacologyMorphine has a crucial role in treating both moderate to severe pain and chronic pain. However, prolonged administration of morphine can lead to tolerance of analgesia, resulting in increased doses and poor treatment of pain. Many patients, such as those
Xiangning Zhang +9 more
doaj +1 more source
, 1995 The pharmacokinetics of morphine in plasma and the distribution of morphine and its glucuronidated metabolites within the cerebrospinal fluid were investigated in rabbits.
Albrecht Ziegler +2 more
core +1 more source
Analgesic use, safety and pharmacokinetics of acetaminophen in equids: A structured scoping review
Equine Veterinary Journal, EarlyView.Abstract Background Despite its frequent use in equine clinical practice, scientific data on the use of acetaminophen in horses remain limited. Objective To map and critically appraise the available evidence on the analgesic use, safety and pharmacokinetics of acetaminophen in horses. Study Design Structured scoping review.
Francisco Medina‐Bautista +2 more
wiley +1 more source
Journal of the Science of Food and Agriculture, EarlyView.Abstract Since the early 1960s, nanotechnology has been a critical area of science, allowing for the development of sophisticated nanomaterials. Nanofibers, one of the most widely used nanotechnological drug delivery systems, have emerged as a highly versatile platform within modern pharmaceutical sciences.
Heybet Kerem Polat +7 more
wiley +1 more source
Archaeometry, EarlyView., 2022 Abstract Organic residue analysis was conducted on various vessels from burials at Tel Yehud, Israel. The analyses led to new reliable evidence for the presence of opioid alkaloids and their decomposition products. This research revitalizes a decades‐old discussion on the presence and function of the opium trade across a cultural region of utmost ...
Vanessa Linares +5 more
wiley +1 more source
Effect of Potassium Channel Modulators on Morphine Withdrawal in Mice
, 2010 The present study was conducted to investigate the effect of potassium channel openers and blockers on morphine withdrawal syndrome. Mice were rendered dependent on morphine by subcutaneous injection of morphine; four hours later, withdrawal was induced ...
Mushtaq Ahmad +4 more
core +1 more source
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT The study aimed to investigate the effect of thoracic paravertebral block (TPVB) with liposomal bupivacaine (LB) before anesthesia induction on postoperative pain, quality of recovery (QoR), and opioid consumption in older patients after video‐assisted thoracoscopic surgery (VATS).
Wen‐Cheng Shi +4 more
wiley +1 more source
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT The study aimed to compare the use of liposomal bupivacaine (LB) and ropivacaine hydrochloride (RH) in combined thoracic paravertebral block (TPVB) and serratus anterior plane block (SAPB) during video‐assisted thoracoscopic surgery (VATS).
Lu Jin, Lian Tang
wiley +1 more source
, 2009 Morphine, a mu-opioid agonist, suppressed the Ca2+dependent release of glutamate that was evoked by exposing cerebrocortical synaptosomes to the potassium channel blocker 4-aminopyridine.
楊聰財;洪啟峰;李憶菁;蘇銘嘉;王素珍 +1 more
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