Activation of Spinal Anti-analgesic System Following Electroacupuncture Stimulation in Rats
We evaluated the interaction between electroacupuncture (EA)-induced antinociception and an endogenous anti-analgesic system. EA was applied to the ST-36 acupoint for 45 min in male Sprague-Dawley rats, and pain thresholds were assessed by the hind-paw ...
Yohji Fukazawa +7 more
doaj +1 more source
ABSTRACT The study aimed to compare the use of liposomal bupivacaine (LB) and ropivacaine hydrochloride (RH) in combined thoracic paravertebral block (TPVB) and serratus anterior plane block (SAPB) during video‐assisted thoracoscopic surgery (VATS).
Lu Jin, Lian Tang
wiley +1 more source
Amniotic-Fluid Ingestion Enhances\ud Morphine Analgesia During Morphine\ud Tolerance and Withdrawal in Rats [PDF]
Ingestion of placenta and amniotic fluid has been shown to enhance opioid-mediated analgesia in rats produced by morphine injection. footshock, vaginal/cervical stimulation, and during late pregnancy.
Doerr, Jean C., Kristal, Dr. Mark B.
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Microglia in morphine tolerance: cellular and molecular mechanisms and therapeutic potential
Morphine has a crucial role in treating both moderate to severe pain and chronic pain. However, prolonged administration of morphine can lead to tolerance of analgesia, resulting in increased doses and poor treatment of pain. Many patients, such as those
Xiangning Zhang +9 more
doaj +1 more source
Effects of aqueous saffron extract (Crocus sativus L.) on the acquisition and reinstatement of morphine-induced conditioned place preference in mice [PDF]
Objective: In the present study, the effects of aqueous saffron extract (Crocus sativus L.) on the acquisition and reinstatement of morphine-induced conditioned place preference (CPP) in mice were investigated.
Hossein Hosseinzadeh +2 more
doaj
Mitogen-Activated Protein Kinase Signaling Mediates Morphine Induced-Delayed Hyperalgesia
The use of morphine, the standard opioid drug, is limited by its undesirable effects, such as tolerance, physical dependence, and hyperalgesia (increased pain sensitivity).
Bárbara Guimaraes de Freitas +6 more
doaj +1 more source
Postoperative Effects of Celecoxib on Opioid Use and Pain Control After Benign Oropharyngeal Surgery
This study evaluated how the addition of celecoxib to a multimodal pain regimen following tonsillectomy + adenoidectomy, or uvulopalatopharyngoplasty (UPPP) + tonsillectomy affects postoperative opioid use and pain control. Patients who received celecoxib consumed significantly fewer opioids compared to the historic control group, with similar ...
Alana Platukus +9 more
wiley +1 more source
Morphine-induced immunosuppression: Effects of protein kinase C activation in lymphocytes [PDF]
The present investigation describes effects of morphine on lymphocyte activation. It is reported here that bypassing the early events of signal transduction by direct protein kinase C (PKC) stimulation with phorbol myristate acetate (PMA), the initial ...
Abha Arya Saini (16768341)
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ABSTRACT Background Epidural analgesia is commonly used for pain control after major lower‐limb orthopedic surgery in children, but it is associated with a risk of postoperative urinary retention. Consequently, urinary catheters are often placed and left in situ for the full duration of epidural analgesia, despite the potential risks of prolonged ...
Idan Katz +6 more
wiley +1 more source
Patient-controlled analgesia in the pediatric population: morphine versus hydromorphone [PDF]
Matthew DiGiusto,2 Tarun Bhalla,1 David Martin,1 Derek Foerschler,3 Megan J Jones,2 Joseph D Tobias1 1Department of Anesthesiology and Pain Medicine, Nationwide Children's Hospital and the Ohio State University, 2The Ohio State School of Medicine ...
Foerschler D +5 more
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