Results 111 to 120 of about 50,460 (257)

Efficacy of Ultrasound‐Guided Intercostal Nerve Block With Liposomal Bupivacaine for Treating Postherpetic Neuralgia in Adult Patients

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT The study aimed to investigate the efficacy of ultrasound‐guided intercostal nerve block (ICNB) with liposomal bupivacaine (LB) comparing ropivacaine‐dexamethasone (RD) for treating postherpetic neuralgia (PHN) in adult patients. A total of 108 patients were randomized 1:1 to receive ICNB with LB or ICNB with RD.
Jin Li, Xiang‐Yu Fang
wiley   +1 more source

Tolerance to Morphine Analgesia: Influence of Pain and Method of Morphine Delivery

open access: yesPain Research and Management, 2000
Whether some kinds of pain can modify the development of tolerance to morphine analgesia is a controversial issue. Clinically, the development of tolerance is often difficult to establish because many factors can contribute to a decline in analgesic ...
Scott A Chen, Anthony L Vaccarino
doaj   +1 more source

Developing the Dopamine D3 Receptor (D3R) Antagonist, (R)‐VK4‐116, as a Non‐Opioid Medication for the Treatment of Opioid Use Disorder

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Opioid use disorder (OUD) remains a major global health challenge, and currently approved treatments (methadone, buprenorphine, and naltrexone) are all opioid receptor‐targeting drugs with limitations in access, adherence, stigma, and use in polysubstance use disorders. Because the dopamine D3 receptor (D3R) is enriched in limbic brain regions
Chia‐Kuei Wu   +15 more
wiley   +1 more source

Analysis and pharmacokinetics of morphine and morphine-6-glucuronide. [PDF]

open access: yes, 2018
The behaviour of morphine and morphine glucuronides has been defined in an attempt to overcome the confusion surrounding the pharmacokinetics of morphine and the potential contribution of the active metabolite morphine-6-glucuronide (M6G), to the ...
Chapman, David John.
core   +1 more source

Gene Expression Profile of Calcium/Calmodulin-Dependent Protein Kinase IIα in the Rat Hippocampus during Morphine Withdrawal

open access: yesBasic and Clinical Neuroscience, 2013
Introduction: Calcium/calmodulin-dependent protein kinase II (CaMKII) is highly expressed in the hippocampus, which has a pivotal role in reward-related memories and morphine dependence.
Shamseddin Ahmadi   +3 more
doaj  

Repurposing antimicrobial agents for neuroprotection: Mechanisms, clinical potential, and challenges

open access: yesNeuroprotection, EarlyView.
Antimicrobial agents exert neuroprotective effects through modulation of interconnected pathways. Tetracyclines, macrolides, antimalarial agents, sulfones, and antiparasitic agents suppress neuroinflammation, oxidative stress, and apoptosis while preserving mitochondrial function and neurotransmission.
Mohammad Amin Manavi   +5 more
wiley   +1 more source

Safety and Efficacy of the Versius Surgical System in Transoral Robotic Surgery: A Prospective Study

open access: yesOtolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To evaluate the safety and feasibility of the Versius surgical robotic system for transoral robotic surgery in benign and malignant head and neck indications. Study Design Open‐label, prospective, single‐arm, phase II clinical trial. Setting Liverpool Head and Neck Centre, United Kingdom. Methods Between December 2023 and March 2025,
Jason C. Fleming   +11 more
wiley   +1 more source

MORPHINE AND HISTAMINE RELEASE

open access: yes, 1958
A wide range of drugs exert analeptic action in dogs treated with morphine; cyclizine, diphenhydramine, chlorcyclizine, Avil, tripelennamine and succinic acid. Benactyzine and Pacatal are without effect. Histamine and an antihistaminase (isoniazid) exert
F H Shaw, S Gershon
core   +1 more source

Percutaneous peripheral nerve stimulation as an ancillary treatment following nerve repair surgery

open access: yesPM&R, EarlyView.
Abstract Background Neuropathic pain after peripheral nerve injury severely degrades quality of life. Peripheral nerve stimulation (PN‐Stim) is cleared by the U.S, Food and Drug Administration for the treatment of acute and chronic pain. This broad indication supports its potential use at the time of peripheral nerve repair in patients reporting ...
Shyam Maisuria   +4 more
wiley   +1 more source

Morphine nitrate and morphine acetate

open access: yes, 2006
n ...
Engelhardt, H., Winters, O. E.
openaire   +1 more source

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