Results 121 to 130 of about 50,460 (257)
Previous studies demonstrated that drug cues could elicit drug-like or withdrawal-like effect, both subjectively and physiologically. However, few studies have compared the central activities induced by a drug-related environment and the drug itself. The
C. L. Cui +8 more
core
Abstract Background Regulatory complaints provide insight into physician performance and professionalism. Although complaint patterns have been described for the collective physician workforce, little is known about complaint risk among physical medicine and rehabilitation (PM&R) specialists (physiatrists).
Nigel Ashworth +5 more
wiley +1 more source
Prenatal exposure to morphine can alter the capacities for learning and memory and the sensitivity to drugs of abuse in progeny. In the present study, we examined the effects of morphine during chick embryonic period of 5-8, 9-12, 13-16 and 17-20 on ...
Sui, Nan +4 more
core
Abstract Intranasal diamorphine (IND), approved for managing breakthrough pain in the UK, has been identified as an acceptable alternative offering effective, expedient, and less traumatic analgesia for children. However, the current dose regimen in pediatric populations relies on clinical expertise while the pharmacokinetics properties are poorly ...
Lianjin Cai +6 more
wiley +1 more source
ABSTRACT Enhanced Recovery After Surgery (ERAS) protocols for cesarean deliveries (CDs) utilize multimodal pain management strategies that often include gabapentin. While gabapentin is excreted in breast milk, its pharmacokinetics in immediately postpartum lactating women are not known. This observational pharmacokinetic study (NCT05099484) enrolled 21
Rebecca Silvola +9 more
wiley +1 more source
Morphine-3-glucuronide prevents tolerance to morphine-6-glucuronide in mice
Daily subcutaneous (s.c.) pretreatment with morphine-3-glucuronide (6 mg/kg) was found to reduce morphine-6-glucuronide (4 mg/kg s.c.)-induced antinociception, with no decrease in the effect over 5 days. Morphine-6-glucuronide administration (4 mg/kg s.c.
Olaso, M. Jesús +2 more
core +1 more source
Oxaziridines: Versatile Reagents in Modern Organic Synthesis
Being capable of transferring an O atom and N‐group/atom, oxaziridines are considered multitasking agents. These are employed for diverse organic transformations, such as epoxidation of olefins, α‐ and γ‐hydroxylation/amination of carbonyl compounds, oxidation of sulfides, [3+2]cycloaddition with unsaturated systems.
Ajeet Chandra +2 more
wiley +1 more source
Morphine-3-glucuronide - a potent antagonist of morphine analgesia
In this study, morphine-3-glucuronide (M3G), the major plasma and urinary metabolite of morphine, was shown to be a potent antagonist of morphine analgesia when administered to rats by the intra-cerebroventricular (i.c.v.) route.
Cramond T., Smith M.T., Watt J.A.
core +1 more source
Abstract Background The combination of femoral and sciatic nerve blocks offers adequate perioperative analgesia for goats undergoing stifle surgery. However, postoperatively, residual motor dysfunction may lead to distress and discomfort. This study evaluated whether combined saphenous and sciatic nerve blocks provide adequate perioperative analgesia ...
Xavier Torruella +6 more
wiley +1 more source
The role of GABAB receptors in morphine self-administration
Background: There is only little information about the effects of GABA receptors agonist and antagonist on morphine self-administration. Present study was designed to assess role of GABAB receptors in the regulation of morphine-reinforced self ...
Effat Ramshini +4 more
doaj

