Results 121 to 130 of about 50,460 (257)

A comparison between spontaneous electroencephalographic activities induced by morphine and morphine-related environment in rats

open access: yes, 2007
Previous studies demonstrated that drug cues could elicit drug-like or withdrawal-like effect, both subjectively and physiologically. However, few studies have compared the central activities induced by a drug-related environment and the drug itself. The
C. L. Cui   +8 more
core  

Regulatory complaint patterns in physical medicine and rehabilitation: A population‐based cohort study

open access: yesPM&R, EarlyView.
Abstract Background Regulatory complaints provide insight into physician performance and professionalism. Although complaint patterns have been described for the collective physician workforce, little is known about complaint risk among physical medicine and rehabilitation (PM&R) specialists (physiatrists).
Nigel Ashworth   +5 more
wiley   +1 more source

The effects of morphine at different embryonic ages on memory consolidation and rewarding properties of morphine in day-old chicks

open access: yes, 2010
Prenatal exposure to morphine can alter the capacities for learning and memory and the sensitivity to drugs of abuse in progeny. In the present study, we examined the effects of morphine during chick embryonic period of 5-8, 9-12, 13-16 and 17-20 on ...
Sui, Nan   +4 more
core  

Intranasal diamorphine population pharmacokinetics modeling and simulation in pediatric breakthrough pain

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 435-447, March 2025.
Abstract Intranasal diamorphine (IND), approved for managing breakthrough pain in the UK, has been identified as an acceptable alternative offering effective, expedient, and less traumatic analgesia for children. However, the current dose regimen in pediatric populations relies on clinical expertise while the pharmacokinetics properties are poorly ...
Lianjin Cai   +6 more
wiley   +1 more source

Population Pharmacokinetics and Transfer of Gabapentin When Used as a Pain Adjunct for Cesarean Deliveries

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 551-560, March 2025.
ABSTRACT Enhanced Recovery After Surgery (ERAS) protocols for cesarean deliveries (CDs) utilize multimodal pain management strategies that often include gabapentin. While gabapentin is excreted in breast milk, its pharmacokinetics in immediately postpartum lactating women are not known. This observational pharmacokinetic study (NCT05099484) enrolled 21
Rebecca Silvola   +9 more
wiley   +1 more source

Morphine-3-glucuronide prevents tolerance to morphine-6-glucuronide in mice

open access: yes, 1997
Daily subcutaneous (s.c.) pretreatment with morphine-3-glucuronide (6 mg/kg) was found to reduce morphine-6-glucuronide (4 mg/kg s.c.)-induced antinociception, with no decrease in the effect over 5 days. Morphine-6-glucuronide administration (4 mg/kg s.c.
Olaso, M. Jesús   +2 more
core   +1 more source

Oxaziridines: Versatile Reagents in Modern Organic Synthesis

open access: yesThe Chemical Record, EarlyView.
Being capable of transferring an O atom and N‐group/atom, oxaziridines are considered multitasking agents. These are employed for diverse organic transformations, such as epoxidation of olefins, α‐ and γ‐hydroxylation/amination of carbonyl compounds, oxidation of sulfides, [3+2]cycloaddition with unsaturated systems.
Ajeet Chandra   +2 more
wiley   +1 more source

Morphine-3-glucuronide - a potent antagonist of morphine analgesia

open access: yes, 1990
In this study, morphine-3-glucuronide (M3G), the major plasma and urinary metabolite of morphine, was shown to be a potent antagonist of morphine analgesia when administered to rats by the intra-cerebroventricular (i.c.v.) route.
Cramond T., Smith M.T., Watt J.A.
core   +1 more source

Perioperative analgesia and postoperative motor function after saphenous and sciatic nerve blocks in goats undergoing bilateral stifle surgery: A pilot study

open access: yesVeterinary Record, EarlyView.
Abstract Background The combination of femoral and sciatic nerve blocks offers adequate perioperative analgesia for goats undergoing stifle surgery. However, postoperatively, residual motor dysfunction may lead to distress and discomfort. This study evaluated whether combined saphenous and sciatic nerve blocks provide adequate perioperative analgesia ...
Xavier Torruella   +6 more
wiley   +1 more source

The role of GABAB receptors in morphine self-administration

open access: yesInternational Journal of Preventive Medicine, 2013
Background: There is only little information about the effects of GABA receptors agonist and antagonist on morphine self-administration. Present study was designed to assess role of GABAB receptors in the regulation of morphine-reinforced self ...
Effat Ramshini   +4 more
doaj  

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