Results 141 to 150 of about 50,460 (257)

Prescribed pharmaceutical alternatives initiative coinciding with reductions in unregulated street opioid use among young people who use drugs: An interrupted time series analysis

Addiction, EarlyView.
Abstract Background and aims In British Columbia, Canada, an initiative was implemented in 2020 to reduce overdose mortality by prescribing pharmaceutical opioids (primarily hydromorphone) as a substitute for the toxic unregulated drug supply. This study estimated changes in the level and trend of unregulated opioid use and non‐prescribed hydromorphone
Erica McAdam, Mohammad Karamouzian, Michael John Milloy, Carmen Verdicchio, Eric C. Sayre, Kanna Hayashi, Thomas Kerr, Kora DeBeck   +7 more
wiley   +1 more source

Substance‐free and substance‐related reinforcement in relation to substance use: A meta‐analysis

Addiction, EarlyView.
Abstract Background and aims Contemporary behavioral economic theory conceptualizes addiction as an operant reinforcer pathology in which substance use is substantively influenced by reinforcement obtained through substance‐free sources. The aim of the current meta‐analysis was to quantitatively synthesize cross‐sectional associations between both ...
Brian M. Bird, Molly L. Garber, Samuele F. Acuff, Keanan J. Joyner, James G. Murphy, James MacKillop   +5 more
wiley   +1 more source

Methylenedioxymethamphetamine (MDMA)‐related fatal poisoning in Australia, 2016 to 2025: Trends, characteristics and toxicology

Addiction, EarlyView.
Abstract Aims To determine: (1) Population rates of fatal methylenedioxymethamphetamine (MDMA)‐related poisoning over the period 2016–2023, years with high closure rates in the National Coronial Information System (NDIS); (2) the case characteristics of known cases of fatal MDMA‐related poisoning, 2016–2025; and (3) whether there have been changes in ...
Shane Darke, Johan Duflou, Agata Chrzanowska, Michael Farrell, Julia Lappin, Amy Peacock   +5 more
wiley   +1 more source

Modulation of medial prefrontal cortical dopamine on the expression of morphine-induced sensitization in rats

, 2004
Rats were administered morphine (5mg•kg-1, i.p.) or saline for seven days and tested with intra-mPFC (medial prefrontal cortex) microinjection of D1 receptor agonist SKF38393 (0-2.0 μg/side), or D1 receptor antagonist SCH23390 (0-1.0 μg/side).
Y. H. Li, J. Liu, X. J. Luo, X. G. Zheng, B. P. Tan   +4 more
core  

Chronic pain treatment experiences and barriers among opioid agonist treatment participants who inject drugs: A qualitative study

Addiction, EarlyView.
Abstract Background and aim Co‐occurring chronic pain affects nearly half of people receiving opioid use disorder (OUD) treatment. Although this pain is often severe, it is usually inadequately managed. Stigma and clinical complexity associated with OUD are thought to further restrict access to pain care.
Jie Yang, Shelley Walker, Amy G. McNeilage, Peter Higgs, Louisa Picco, Paul Dietze, Suzanne Nielsen   +6 more
wiley   +1 more source

Systematic Literature Review of Spinal Cord Stimulation in Patients With Chronic Back Pain Without Prior Spine Surgery

Neuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Objective Low back pain is the leading cause of disability worldwide and one of the most common reasons for seeking healthcare. Despite numerous care strategies, patients with low back pain continue to exhibit poor outcomes. Spinal cord stimulation (SCS) is an evidence‐based therapeutic modality for patients with failed back surgery syndrome ...
Jan M. Eckermann, Julie G. Pilitsis, Christopher Vannaboutathong, Belinda J. Wagner, Rose Province‐Azalde, Markus A. Bendel   +5 more
wiley   +1 more source

Probable cychlorphine exposure in a patient with opioid use disorder: A case report

The American Journal on Addictions, EarlyView.
Abstract Background and Objectives Cychlorphine is an emerging synthetic opioid with limited clinical data. Methods We describe a patient's reported cychlorphine use and its's clinical effects. Results Thirty‐five years old male with opioid use disorder reported purchasing cychlorphine online.
Manroop Bal, Nimna Mendis, Melissa Bennett, David Kinniburgh, Jeremy Weleff   +4 more
wiley   +1 more source

The Fruit Essential oil of Cuminum cyminum L. Reduced the Acquisition but not Expression of Ineffective dose of Morphine-Induced Conditioned Place Preference in Morphine- Sensitized Mice

Journal of Medicinal Plants, 2009
Background: Cuminum cyminum fruit essential oil (FEO) dose-dependently can attenuate the expression of morphine tolerance and dependence in morphine-dependent mice.
A Haghparast, J Zarringhalam, A Khatibi, E Dianati, J Shams   +4 more
doaj  

Morphin

Delaware Journal of Public Health, 2017
openaire   +3 more sources

Awareness campaign about lethal drug 600 times stronger than morphine.

, 2016
Family and friends of heroin users are being targeted in a public awareness campaign about, fentanyl, a lethal drug that is up to 600 times stronger than ...
Ring, Evelyn
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