Results 91 to 100 of about 50,460 (257)

Effects of aqueous saffron extract (Crocus sativus L.) on the acquisition and reinstatement of morphine-induced conditioned place preference in mice [PDF]

open access: yesAvicenna Journal of Phytomedicine, 2011
Objective: In the present study, the effects of aqueous saffron extract (Crocus sativus L.) on the acquisition and reinstatement of morphine-induced conditioned place preference (CPP) in mice were investigated.
Hossein Hosseinzadeh   +2 more
doaj  

Mitogen-Activated Protein Kinase Signaling Mediates Morphine Induced-Delayed Hyperalgesia

open access: yesFrontiers in Neuroscience, 2019
The use of morphine, the standard opioid drug, is limited by its undesirable effects, such as tolerance, physical dependence, and hyperalgesia (increased pain sensitivity).
Bárbara Guimaraes de Freitas   +6 more
doaj   +1 more source

Population‐Stratified Distributions of Post‐Mortem Blood Drug Concentrations: An Epidemiological Framework for Contextual Interpretation

open access: yesDrug Testing and Analysis, EarlyView.
Post‐mortem blood drug concentrations exhibit substantial overlap between deaths in which a drug was implicated and those in which it was not. Analysis of over 58,000 NPSUM cases demonstrates that demographic stratification does not resolve this uncertainty, reinforcing the need for contextual, evidence‐based interpretation rather than concentration ...
Thikra Algahtani   +6 more
wiley   +1 more source

Intra‐Individual Variability of Blood and Urinary Steroid Markers and the Response to Codeine Intake in Healthy Men and Women

open access: yesDrug Testing and Analysis, EarlyView.
Short‐term codeine administration (1–3 days) caused individual alterations in Athlete Biological Passport steroid markers, including elevated urinary T/E ratios and decreased serum testosterone concentrations below individual thresholds, despite no significant changes at the group level.
Alexander Andersson   +5 more
wiley   +1 more source

Behavioral Consequences of Delta-Opioid Receptor Activation in the Periaqueductal Gray of Morphine Tolerant Rats

open access: yesNeural Plasticity, 2009
Chronic morphine administration shifts delta-opioid receptors (DORs) from the cytoplasm to the plasma membrane. Given that microinjection of morphine into the PAG produces antinociception, it is hypothesized that the movement of DORs to the membrane will
Michael M. Morgan   +3 more
doaj   +1 more source

Fatalities within seven days after equine standing sedation: A prospective, multicentre study

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background Information regarding mortality associated with standing procedures in horses is sparse. Objectives To report data from >12,000 standing sedations. Study Design Confidential, observational, prospective, multicentre, cohort study.
Miguel Gozalo‐Marcilla   +6 more
wiley   +1 more source

Research Note: Morphine influences circulating and tissue concentrations of met-enkephalin and proenkephalin (PENK) expression and plasma concentrations of corticosterone in chickens

open access: yesPoultry Science
: The effects of the administration of the opioid agonist, morphine, on plasma and tissue concentrations of Met-enkephalin were determined in 14 wk old female chickens.
Colin G. Scanes   +1 more
doaj   +1 more source

Oral diacetylmorphine (heroin) yields greater morphine bioavailability than oral morphine: bioavailability related to dosage and prior opioid exposure

open access: yes, 2008
AIMS: In the Swiss heroin substitution trials, patients are treated with self-administered diacetylmorphine (heroin). Intravenous administration is not possible in patients that have venosclerosis.
Eich-Höchli, D   +9 more
core   +1 more source

Laser neoureterocystostomy to treat ectopic ureters

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background Ureteral ectopia is an uncommon but clinically important congenital abnormality in horses. If left untreated, it can lead to persistent dermatitis, urinary tract infections, and failure to thrive. Surgical correction is necessary, but traditional approaches have produced mixed results with high morbidity.
Caitlin Smith, Eric J. Parente
wiley   +1 more source

Effects of Testosterone on Analgesia in Formalin-Treated Mice

open access: yesJournal of Ardabil University of Medical Sciences, 2018
CT   Background & objectives: So far, various reports have been presented on the relationship between sex hormones and gender-related differences in pain and analgesia in humans and laboratory animals.
Akram Alijani   +3 more
doaj  

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