Results 31 to 40 of about 176,329 (291)
Introduction: The endocannabinoid system has been implicated in the neurobiology of opioid use disorder. While the CB1 receptor antagonist rimonabant has been shown to block some of the behavioral effects of opioids, studies suggest that the treatment ...
Eduardo A. V. Marinho +12 more
doaj +1 more source
An evaluation of palliative care in rural Tanzania where availability of oral morphine is intermittent or absent [PDF]
Includes bibliographical details.In Tanzania, palliative care is relatively new, and faces the common challenges of access to services, crucial medications, and education.
Hartwig, Kristopher
core +1 more source
We previously showed that subsequent intrathecal (i.t.) injection of resveratrol (30 μg) significantly reverses morphine-evoked neuroinflammation in morphine-tolerant rats. The present study examined the underlying mechanism.
Ru-Yin Tsai +4 more
doaj +1 more source
In morphine intoxication cases, forensic toxicologists are frequently confronted with the question of if the individual was opioid-tolerant or opioid-naïve, which can be investigated by hair analysis. However, interpretation of results can be challenging.
Milena M. Madry +4 more
doaj +1 more source
Morphine pre-exposure facilitates reinstatement but attenuates retention of morphine-induced place preference [PDF]
BACKGROUND: Drug-associated conditioned stimuli are a key factor to induce morphine relapse. To date, limited evidence is available regarding the impact of drug history on propensity or vulnerability to relapse after long-term abstinence.
Yang, Xiaoyan +4 more
core +1 more source
The Effect of Memantine on the Expression of Dopamine Receptors in the Striatum of Male Rats With Morphine Addiction [PDF]
Background and Objectives: Studies have indicated that the chronic use of morphine can result in physical and psychological dependence. Morphine dependence is associated with several cellular and molecular alterations in the mesocorticolimbic system, and
Sahar Khalili Samani +5 more
doaj
Mitochondria‐targeted nanotherapies emerge as a promising strategy for combating aging‐associated neurodegenerative disorders (NDs) by restoring mitochondrial function, reducing oxidative stress, and improving neuronal survival. Recent advances in nanotechnology, therapeutic delivery, and translational research are highlighted, providing insights into ...
Dnyandev G. Gadhave +8 more
wiley +1 more source
A multifunctional regenerative composite is constructed by 3D‐printing thermosensitive PNIPAM hydrogel embedded with MPDA@IL‐10 nanoparticles and autologous BMSCs onto antigen‐depleted porcine bone matrix for beagle critical‐sized skull defect reconstruction.
Weihao Lv +16 more
wiley +1 more source
The preparation of the diastereomerically pure β-tetralone ketal 4 is reported. Intramolecular alkylidene C−H insertion followed by hydrolysis of 4 proceeded to give the enantiomerically pure cyclopentene 15.
Arnold L. Rheingold (1274736) +2 more
core +2 more sources

