Results 31 to 40 of about 161,700 (313)

Effect of Intrathecal Morphine on Postdural Puncture Headache in Obstetric Anaesthesia [PDF]

open access: yes, 2023
Objective:Intrathecal morphine is used as an effective component of multimodal analgesia in postoperative analgesia in cesarean section patients. We aimed to analyze the relationship between intrathecal morphine administration and postdural puncture ...
Arda Işıker   +4 more
core   +1 more source

Senolytic Therapy as a Preventive Strategy for Spine Degeneration and Pain

open access: yesAdvanced Science, EarlyView.
Cellular senescence promotes inflammation, tissue degeneration, and chronic back pain. In sparc‐null mice, early oral administration of the senolytic agents o‐vanillin and RG‐7112 reduced senescent cell burden and pro‐inflammatory SASP signaling across intervertebral discs, endplates, vertebral bone, and spinal cord.
Saber Ghazizadeh   +7 more
wiley   +1 more source

The Effect of Memantine on the Expression of Dopamine Receptors in the Striatum of Male Rats With Morphine Addiction [PDF]

open access: yesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2023
Background and Objectives: Studies have indicated that the chronic use of morphine can result in physical and psychological dependence. Morphine dependence is associated with several cellular and molecular alterations in the mesocorticolimbic system, and
Sahar Khalili Samani   +5 more
doaj  

Editorial Commentary: The Pericapsular Nerve Group Block in Hip Arthroscopy: Not a Miracle—But Ignoring It Is No Longer an Option

open access: yesArthroscopy, EarlyView.
Abstract Postoperative pain control remains a central determinant of discharge readiness, patient satisfaction, and opioid exposure after hip arthroscopy. Even modest improvements in early analgesia can meaningfully influence recovery pathways.
Alexander Zimmerer
wiley   +1 more source

Effets d'un traitement chronique par la morphine sur le protéome des cellules de neuroblastome humain SH-SY5Y [PDF]

open access: yes, 2007
Afin de mieux comprendre les adaptations cellulaires induites suite à une prise chronique de morphine, une stratégie de type protéomique différentielle combinant les techniques d'électrophorèse et de spectrométrie de masse a été entreprise dans des ...
Mouledous, Lionel
core  

Perioperative Intravenous Dexamethasone Improves Pain and Functional Outcomes After Arthroscopic Rotator Cuff Repair

open access: yesArthroscopy, Sports Medicine, and Rehabilitation, EarlyView.
Purpose To evaluate the effect of perioperative dexamethasone on patient‐reported pain, functional outcomes, and minimal clinically important difference (MCID) achievement following arthroscopic rotator cuff repair. Methods Patients who underwent rotator cuff repair between 2013 and 2023 were identified and divided into groups.
Trevor D. Wolterink   +9 more
wiley   +1 more source

Morphine Induces Apoptosis of Human Endothelial Cells through Nitric Oxide and Reactive Oxygen Species Pathways

open access: yes, 2011
Morphine has been widely used for pain management. Other than analgesia, it has effects on vascular endothellial cells, including angiogenesis and apoptosis.
蕭柏妮;張明誠;鄭文芳;陳祈安;林漢威;謝長堯;孫維仁   +1 more
core   +1 more source

Prescribing competence: The pros and cons of different methods for assessment

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Evaluating a medical graduate’s competence in rational prescribing is challenging. With the aim to guide and inspire teachers, this narrative review explores different methods that can be used to assess prescribing competence. Each method has its own advantages and disadvantages, and thus a mix of different assessment methods is needed throughout the ...
David J. Brinkman   +3 more
wiley   +1 more source

Morphine-induced taste aversions : A consideration of parameters

open access: yes, 1978
Following consumption of saccharin, groups of rats were injected with various doses of morphine sulfate. Although no aversion was found after one conditioning trial, repeated saccharin-morphine pairings resulted in decreases in consumption of the ...
W.J. Jacobs (16783884)   +2 more
core   +1 more source

Beyond the label: Rethinking off‐label drug use in paediatrics. Towards a scientifically grounded and safer future for paediatric pharmacotherapy

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Despite regulatory progress being made in the past two decades, off‐label drug use in paediatrics remains pervasive, with prevalence estimated between 3% and 97% of prescriptions across different clinical settings. Off‐label use—defined as prescribing outside the conditions described in the Summary of Product Characteristics (SmPC)—is often ...
Tjitske M. van der Zanden   +3 more
wiley   +1 more source

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