Basic and Clinical Neuroscience, 2020 Introduction: The GABAergic system of the brain plays a key role in morphine tolerance and sensitization. As isoniazid is a modulator of the GABAergic system, the present study aims to understand whether isoniazid can influence the induction of tolerance
Amir Abbas Barzegari, Kamran Shahabi
doaj
Tolerance to Morphine Analgesia: Influence of Pain and Method of Morphine Delivery
Pain Research and Management, 2000 Whether some kinds of pain can modify the development of tolerance to morphine analgesia is a controversial issue. Clinically, the development of tolerance is often difficult to establish because many factors can contribute to a decline in analgesic ...
Scott A Chen, Anthony L Vaccarino
doaj +1 more source
IV.—Action of the organic acids and their anhydrides on the natural alkaloids. Part II. Butyryl and benzoyl derivatives of morphine and codeine [PDF]
, 1875 G. H. Beckett, C. R. Alder Wright
openalex +1 more source
Learning Health Systems, EarlyView.Abstract Introduction (1) Assess the harmonization of structured electronic health record data (laboratory results and medications) to reference terminologies and characterize the severity of issues. (2) Identify issues of data completeness by comparing complementary data domains, stratifying by time, care setting, and provenance.
Keith Marsolo +14 more
wiley +1 more source
Mitogen-Activated Protein Kinase Signaling Mediates Morphine Induced-Delayed Hyperalgesia
Frontiers in Neuroscience, 2019 The use of morphine, the standard opioid drug, is limited by its undesirable effects, such as tolerance, physical dependence, and hyperalgesia (increased pain sensitivity).
Bárbara Guimaraes de Freitas +6 more
doaj +1 more source
THE EXTRACTION OF MORPHINE WITH IMMISCIBLE SOLVENTS. [PDF]
, 1901 W. A. Puckner
openalex +1 more source
An overview of the non‐procedural treatment options for peripheral neuropathic pain
Muscle &Nerve, EarlyView.Abstract Peripheral neuropathic pain is common in patients with peripheral nerve injury and can significantly impact both their function and quality of life. There is a wide variety of non‐interventional treatment approaches, including pharmacologic therapy, physical/occupational therapy, modalities (therapeutic, mechanical, thermal, etc.), psychology,
Evan R. Zeldin +6 more
wiley +1 more source
The effect of cannabinoid type 2 receptor agonist on morphine tolerance
IBRO Neuroscience ReportsPain highly impacts the quality of life of patients. Morphine is used for pain treatment; however, its side effects, especially morphine tolerance, limit its use in the clinic. The problem of morphine tolerance has plagued health workers and patients for
Di Cui, Yuanyuan Zhang, Mingyue Zhang
doaj
Effects of aqueous saffron extract (Crocus sativus L.) on the acquisition and reinstatement of morphine-induced conditioned place preference in mice [PDF]
Avicenna Journal of Phytomedicine, 2011 Objective: In the present study, the effects of aqueous saffron extract (Crocus sativus L.) on the acquisition and reinstatement of morphine-induced conditioned place preference (CPP) in mice were investigated.
Hossein Hosseinzadeh +2 more
doaj
The Nature of the Work of the Kidney as shown by the Influence of Atropine and Morphine upon the Secretion of Urine [PDF]
, 1893 W. H. Thompson
openalex +1 more source