Results 201 to 210 of about 50,460 (257)
Opioid Prescription Trends by Otolaryngologists for Medicare Part D Patients
Laryngoscope Investigative Otolaryngology, Volume 11, Issue 6, December 2026.Between 2013 and 2024, ENT opioid prescriptions reached a nadir in 2020 with a post pandemic rebound. ABSTRACT Objective To characterize longitudinal trends in opioid prescription patterns among otolaryngologists in the Medicare Part D population spanning the COVID‐19 pandemic, including overall prescribing volume, drug‐type composition, and geographic
Larry W. Wang +5 more
wiley +1 more source
Musculoskeletal Care, Volume 24, Issue 4, December 2026.ABSTRACT Purpose Chronic low back pain (CLBP) is a persistent, debilitating condition. The United States (US) Food and Drug Administration Patient‐Focused Drug Development Guidance recommends using patient‐reported outcome (PRO) measures to assess pain and function in clinical trials and document content validity of the measures based on patient ...
Ekin Seçinti +12 more
wiley +1 more source
Temporal Dilution: Chemotherapy, Capitalism, and the Making of Cancer Time in Colombia
The Journal of Latin American and Caribbean Anthropology, Volume 31, Issue 4, December 2026.ABSTRACT Through the ethnographic case of a man undergoing chemotherapy for prostate cancer at a hospital in Colombia, this article examines how chemotherapy schedules make toxicity clinically manageable while imposing rhythms that many patients cannot sustain. It develops an analytic framework centered on three interrelated temporal dynamics: temporal
Camilo Sanz
wiley +1 more source
Scandinavian Journal of Caring Sciences, Volume 40, Issue 4, December 2026.ABSTRACT Aim To analyse the use of opioids in children with cancer and the experiences of their family members regarding opioids used in pain management to improve family nursing. Design An integrative review. Methods A systematic literature search was carried out in four databases (CINAHL, MEDLINE, PsycInfo and Scopus) in August 2023, and was ...
Noora Puusa +3 more
wiley +1 more source
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Morphine Metabolism and Morphine Tolerance in Goldfish
Anesthesiology, 1970Tolerance to morphine was induced in goldfish shown to be unable to metabolize morphine. Ability to metabolize is, therefore not a prercquisite to development of tolerance.
G A, Jansen, N M, Greene
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Morphine-Induced Attenuation of Morphine Tolerance
Science, 1981Rats experienced both morphine and an environmental cue, but the cue always signaled a drug-free period. They were subsequently administered morphine in the presence of the cue, and the development of analgesic tolerance was assessed. The prior experience retarded such tolerance.
S, Siegel, R E, Hinson, M D, Krank
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Psychopharmacology, 1976
The morphine blocking and anticonvulsant effects of propranolol were investigated in mice. Three different convulsant procedures (electroshock, pentylenetetrazol and thebaine) were used. In addition, LD50's of morphine after different doses of propranolol were done.
G, Navarro, R, Richardson, A T, Zuban
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The morphine blocking and anticonvulsant effects of propranolol were investigated in mice. Three different convulsant procedures (electroshock, pentylenetetrazol and thebaine) were used. In addition, LD50's of morphine after different doses of propranolol were done.
G, Navarro, R, Richardson, A T, Zuban
openaire +2 more sources
Journal of the American Chemical Society, 2002
The preparation of the diastereomerically pure beta-tetralone ketal 4 is reported. Intramolecular alkylidene C-H insertion followed by hydrolysis of 4 proceeded to give the enantiomerically pure cyclopentene 15. The key step in this synthesis was the bis-intramolecular cyclization of keto aldehyde 2 to give the tetracyclic intermediate 20. Enone 20 was
Douglass F, Taber +2 more
openaire +2 more sources
The preparation of the diastereomerically pure beta-tetralone ketal 4 is reported. Intramolecular alkylidene C-H insertion followed by hydrolysis of 4 proceeded to give the enantiomerically pure cyclopentene 15. The key step in this synthesis was the bis-intramolecular cyclization of keto aldehyde 2 to give the tetracyclic intermediate 20. Enone 20 was
Douglass F, Taber +2 more
openaire +2 more sources
Pharmacological Research, 1995
This review surveys the discovery of endogenous alkaloids in mammals. The formation of morphine in mammalian brain was assumed in 1970. The existence of morphine was demonstrated by radioimmunoassay. Identification of morphine was performed by spectroscopic methods. The isolation of mammalian morphine raises the question of biosynthesis.
S, Hosztafi, Z, Fürst
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This review surveys the discovery of endogenous alkaloids in mammals. The formation of morphine in mammalian brain was assumed in 1970. The existence of morphine was demonstrated by radioimmunoassay. Identification of morphine was performed by spectroscopic methods. The isolation of mammalian morphine raises the question of biosynthesis.
S, Hosztafi, Z, Fürst
openaire +2 more sources