Results 181 to 190 of about 162,133 (313)

In silico prediction of novel effective combinational treatment of chronic pain in individual patients: A joint white paper of the H2020 QSPainRelief consortium

British Journal of Pharmacology, EarlyView.
Abstract Opioids are prescribed widely for chronic pain despite well‐recognised risks and variable long‐term benefit, reflecting the lack of effective alternatives for many patients. Combination therapies offer a promising strategy to enhance efficacy whilst reducing side effects.
André Mouraux, Solenn Gousset, Beltrán Alvarez, Monica Baiula, Wouter Bakker, Andrea Bedini, Monir Bertayli, Divakar Budda, Robert Carr, Elisabetta Cuna, Óscar Díaz, Nina Donner, Jesús Giraldo, Geert‐Jan Groeneveld, Berfin Gülave, David Guydan, Hemme Hijma, Rafael Maldonado, Pedro Renault, Carlos Rinaudo, Jeroen Elaissaiss‐Schaap, Athan Spiros, Sara Stoeber, Petri Takkala, Daan van Valkengoed, Coen van Hasselt, Elizabeth (Liesbeth) CM de Lange   +26 more
wiley   +1 more source

Effect of Enzalutamide on Morphine Exposure in Patients with Prostate Cancer. [PDF]

Clin Pharmacokinet
Op 't Hoog CJP, Mehra N, van der Weij B, Olofsen E, Somford DM, van Oort IM, Hamberg P, van Erp NP, Boerrigter E.   +8 more
europepmc   +1 more source

The Morphine Manifesto [PDF]

Tidsskrift for Den norske legeforening, 2012
Ola, Dale, Kristian, Svendsen, Petter C, Borchgrevink   +2 more
openaire   +2 more sources

Underpowered study design invalidates conclusions of LTAP versus LWI in peritoneal endometriosis surgery

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
Ding Li, Song Ye
wiley   +1 more source

Neuronal and ion channel mechanisms of noxious heat sensing in mammals: A puzzle of sensory physiology and pharmacology

British Journal of Pharmacology, EarlyView.
Transient receptor potential vanilloid 1 (TRPV1) was the first noxious heat‐sensitive channel discovered. In rodents, its role is robust in the heat response of the cell body of polymodal nociceptors, but surprisingly small in that of the peripheral terminals in the skin.
Gábor Pethő, Peter W. Reeh
wiley   +1 more source

Intrathecal morphine dose optimization in robotic-assisted laparoscopic hysterectomy: a dual-center cohort study. [PDF]

J Robot Surg
Russo A, Perelli F, Aceto P, Arcieri M, Bernardini F, Pregnolato S, Moroni R, Dogareschi T, Meroi F, Costantini B, Gallotta V, Fanfani F, Driul L, Fagotti A, Bove T, Restaino S, Antonelli M, Vizzielli G.   +17 more
europepmc   +1 more source

Commentary on central sensitization in chronic pelvic pain

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
Shahzadi Gulfishan, Ahmed Raza, Abdullah Aman   +2 more
wiley   +1 more source

Comparison of Long vs. Short Concave Neck in One‐Piece Implants Inserted 1 mm Subcrestally: A Pre‐Clinical In Vivo Study

Clinical Oral Implants Research, EarlyView.
ABSTRACT Objectives The aim was to assess the influence of one‐piece implant concave neck height on soft‐ and hard‐tissue healing on a canine model. Material and Methods Monoblock implants with a transgingival concave neck were randomly inserted 1 mm subcrestally.
Hadi Antoun, Frank Bonnet, María Permuy Mendaña, Daniele Botticelli, Giovanna Iezzi, Morena Petrini   +5 more
wiley   +1 more source

Persistent Mu-Opioid Receptor Dysregulation in a Pain-Facilitatory Brain Region Reinstates Hyperalgesia After Resolution of Opioid-Induced Hyperalgesia. [PDF]

Pharmaceuticals (Basel)
Sousa M, Costa AR, Tavares I, Martins I.
europepmc   +1 more source

Stapled side‐to‐side anastomosis to treat a pelvic flexure stricture in a miniature horse

Equine Veterinary Education, EarlyView.
Summary Fecaliths are a recognised cause of non‐strangulating colon obstruction in horses. Although they more commonly obstruct the small colon, they can also lodge in the pelvic flexure, requiring enterotomy for removal. Stricture at the enterotomy site is an uncommon but surgically significant complication.
M. Baglioni, N. Berka, P. Matrat, L. Legrand, L. Borde‐Dore, C. de Chaisemartin   +5 more
wiley   +1 more source