Results 221 to 230 of about 265,062 (307)

Phenol Neurolysis in Pain and Palliative Medicine

open access: yesPain Practice, Volume 26, Issue 5, June 2026.
ABSTRACT Background Pain is a common symptom in palliative care and affects patients' quality of life considerably. Standard analgesics are sometimes insufficient and are associated with substantial side effects. Neurolysis, the targeted destruction of nerves using thermal or chemical agents, offers an additional option for managing localized pain in ...
Jeroen H. A. Creemers   +6 more
wiley   +1 more source

How Does Symptom Management Affect Quality of Life in Palliative Care Patients? A Descriptive and Correlation Study

open access: yesScandinavian Journal of Caring Sciences, Volume 40, Issue 2, June 2026.
ABSTRACT Aims This study aimed to determine the relationship between symptom management and quality of life in palliative care patients. Methods Data was collected using the Patient Information Form, the Edmonton Symptom Assessment Scale (ESAS), and the EQ‐5D Quality of Life Scale.
Gülşah Çamcı   +3 more
wiley   +1 more source

Cannabinoids and drug–drug pharmacokinetic interactions: Deciphering the risks

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 5, Page 1287-1308, May 2026.
The relationship between cannabinoids and mental health has become a major focus of scientific inquiry and public discourse. Cannabinoids are diverse chemical compounds from the Cannabis species that have been explored for their therapeutic applications in treating chronic pain, psychiatric and neurological conditions, such as depression, schizophrenia,
Paraskevi Papakyriakopoulou   +2 more
wiley   +1 more source

Systematic Management of a Critical CYP3A4 Interaction Between Cabozantinib and Carbamazepine: A Case Report of a Clinically Relevant Pharmacokinetic Interaction

open access: yesClinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT This was the case of a 62‐year‐old patient treated with cabozantinib and nivolumab for metastatic clear cell renal cell carcinoma, in whom a clinically significant pharmacokinetic interaction with carbamazepine was observed. Carbamazepine, a potent inducer of CYP3A4, caused a major decrease in systemic exposure to cabozantinib, as confirmed by
Pierre Nizet   +4 more
wiley   +1 more source

Membrane Permeability Drives the Extreme Potency of Fentanyl. [PDF]

open access: yesJACS Au
Clayton J   +8 more
europepmc   +1 more source

Two Cases of Kounis Syndrome Caused by Contrast Medium: Early Extracorporeal Membrane Oxygenation

open access: yesClinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT In cardiology, Kounis syndrome (KS), also known as allergic angina or myocardial infarction, is often overlooked in emergencies. Its pathophysiology differs from that of allergic reactions such as anaphylaxis, making differentiation essential.
Kiichi Yano   +5 more
wiley   +1 more source

Repeated Tetrahydrocannabinol Injections Induce Tolerance but Do Not Disrupt Ongoing Behaviour Upon Withdrawal in Male and Female Rats With Inflammatory Pain

open access: yesEuropean Journal of Pain, Volume 30, Issue 5, May 2026.
ABSTRACT Background Many people use cannabis to self‐medicate for pain. Little is known about the impact of pain on tolerance and spontaneous withdrawal to delta‐9‐tetrahydrocannabinal (THC), the primary psychoactive compound in cannabis. Our previous research with the opioid morphine suggests persistent pain will increase the magnitude and duration of
Michael M. Morgan, Christa M. Hickey
wiley   +1 more source

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