Results 281 to 290 of about 339,726 (399)

Behavioural and pharmacokinetic analysis of heroin and cocaine self‐administration: Effects of timeout on self‐administration and choice in male rats

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Heroin and cocaine users tailor their dosage, frequency and administration route to maximise the drugs' effects or prevent withdrawal symptoms. Counterintuitively, preclinical self‐administration and choice experiments employ, almost invariably and regardless of the pharmacokinetic properties of the drug under examination, fixed ...
Ginevra D'Ottavio   +18 more
wiley   +1 more source

A Prospective Randomized Dose-Finding Study of Intrathecal Opioids for Postoperative Analgesia After Minimally Invasive Colorectal Operation. [PDF]

open access: yesMayo Clin Proc Innov Qual Outcomes
Vinsard PA   +11 more
europepmc   +1 more source

S-nitrosoglutathione reductase alleviates morphine analgesic tolerance by restricting PKCα S-nitrosation

open access: yesRedox Biology
Morphine, a typical opiate, is widely used for controlling pain but can lead to various side effects with long-term use, including addiction, analgesic tolerance, and hyperalgesia.
Ling-Yan Su   +10 more
doaj  

Patterns of opioid prescribing to opioid‐naive patients after surgical and emergency care: A population‐based cross‐sectional study using linked administrative databases in Nova Scotia (2017–2019)

open access: yesDrug and Alcohol Review, EarlyView.
Abstract Introduction To describe opioid prescribing patterns for opioid‐naive patients who filled prescriptions after surgical or emergency care. Methods We conducted a population‐based, cross‐sectional study of opioid‐naive adults who filled opioid prescriptions within 14 days of receiving surgical or emergency care in Nova Scotia, Canada.
Roah A. Merdad   +4 more
wiley   +1 more source

Dentigerous cysts in horses: A retrospective study

open access: yesEquine Veterinary Education, EarlyView.
Summary Background Dentigerous cysts are well‐known congenital defects in horses, and the literature on this condition is extensive. Recently, a third type of dentigerous cyst, associated with an exostosis arising from the temporal bone, has been described.
M. Schläpfer   +3 more
wiley   +1 more source

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