Results 21 to 30 of about 168,528 (214)

Morphine hydrochloride anhydrate [PDF]

Acta Crystallographica Section E Structure Reports Online, 2012
In the title mol-ecular salt [systematic name: (5α,6α)-7,8-didehydro-4,5-ep-oxy-17-methyl-morphinan-3,6-diol hydro-chloride], C17H20NO3(+)·Cl(-), the conformation of the morphinium ion is in agreement with the characteristics of the previously reported morphine forms [for example, Gylbert (1973 ▶). Acta Cryst. B29, 1630-1635].
Gelbrich, Thomas, Braun, Doris E., Griesser, Ulrich J.   +2 more
openaire   +2 more sources

Context-dependent effects of the CB1 receptor antagonist rimonabant on morphine-induced behavioral sensitization in female mice

Frontiers in Pharmacology, 2023
Introduction: The endocannabinoid system has been implicated in the neurobiology of opioid use disorder. While the CB1 receptor antagonist rimonabant has been shown to block some of the behavioral effects of opioids, studies suggest that the treatment ...
Eduardo A. V. Marinho, Eduardo A. V. Marinho, Alexandre Justo Oliveira-Lima, Alexandre Justo Oliveira-Lima, Henrique S. Reis, Renan Santos-Baldaia, Raphael Wuo-Silva, Andre W. Hollais, Thais S. Yokoyama, Roberto Frussa-Filho, Lais F. Berro, Lais F. Berro, Lais F. Berro   +12 more
doaj   +1 more source

Significance of Metabolite Ratios in the Interpretation of Segmental Hair Testing Results—Differentiation of Single from Chronic Morphine Use in a Case Series

Metabolites, 2021
In morphine intoxication cases, forensic toxicologists are frequently confronted with the question of if the individual was opioid-tolerant or opioid-naïve, which can be investigated by hair analysis. However, interpretation of results can be challenging.
Milena M. Madry, Sandra N. Poetzsch, Andrea E. Steuer, Thomas Kraemer, Markus R. Baumgartner   +4 more
doaj   +1 more source

Morphine Manifesto

Acta Médica Portuguesa, 2016
N ...
openaire   +4 more sources

Resveratrol reverses morphine-induced neuroinflammation in morphine-tolerant rats by reversal HDAC1 expression

Journal of the Formosan Medical Association, 2016
We previously showed that subsequent intrathecal (i.t.) injection of resveratrol (30 μg) significantly reverses morphine-evoked neuroinflammation in morphine-tolerant rats. The present study examined the underlying mechanism.
Ru-Yin Tsai, Juei-Chii Wang, Kuang-Yi Chou, Chih-Shung Wong, Chen-Hwan Cherng   +4 more
doaj   +1 more source

The Effect of Memantine on the Expression of Dopamine Receptors in the Striatum of Male Rats With Morphine Addiction [PDF]

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2023
Background and Objectives: Studies have indicated that the chronic use of morphine can result in physical and psychological dependence. Morphine dependence is associated with several cellular and molecular alterations in the mesocorticolimbic system, and
Sahar Khalili Samani, Solmaz Khalifeh, Mehdi Vahiddastjerdi, Mandana Hassanzad, Afshin Kheradmand, Farzaneh Nazari Serenjeh   +5 more
doaj  

Acute and chronic effects of morphine on Low-Mg2+ ACSF-induced epileptiform activity during infancy in mice hippocampal slices

Research in Pharmaceutical Sciences, 2019
Interaction of morphine and seizure is complex. Mouse brain hippocampal slices were used to estimate how acute and chronic morphine treatment alters the low-magnesium artificial cerebrospinal fluid (LM-ACSF)-induced seizure activity.
Yousef Panahi, Ehsan Saboory, Shiva Roshan-Milani, Leila Drafshpoor, Yousef Rasmi, Ali Rassouli, Goudarz Sadeghi-Hashjin   +6 more
doaj   +1 more source

Dysregulation of Vesicular Glutamate Transporter VGluT2 via BDNF/TrkB Pathway Contributes to Morphine Tolerance in Mice

Frontiers in Pharmacology, 2022
Morphine is widely used in the treatment of moderate to severe pain. Long-term use of morphine leads to various adverse effects, such as tolerance and hyperalgesia.
Liqiong He, Liqiong He, Wei Xu, Chengliang Zhang, Chengliang Zhang, Zhuofeng Ding, Zhuofeng Ding, Qulian Guo, Qulian Guo, Wangyuan Zou, Wangyuan Zou, Jian Wang, Jian Wang   +12 more
doaj   +1 more source

Influence of Nitric Oxide in the Central Amygdala on the Acquisition and Expression of Morphine-Induced Place Preference in Morphine Sensitized Rats

Basic and Clinical Neuroscience, 2011
Effects of intra-central amygdala administration of L-arginine, a nitric oxide precursor, and NG-nitro-L-arginine methyl-ester (L NAME), a nitric oxide synthase inhibitor, on the morphine-induced sensitization and also on the expression of morphine ...
Hedayat Sahraei, Mohammad-Reza Zarrindast, Jamal Shams, Akram Eidi, Hassan Ghoshooni, Homeira Zardooz, Sara Sadeghi-Gharachehdaghi, Sara Bijani   +7 more
doaj   +2 more sources

The effect of cannabinoid type 2 receptor agonist on morphine tolerance

IBRO Neuroscience Reports
Pain highly impacts the quality of life of patients. Morphine is used for pain treatment; however, its side effects, especially morphine tolerance, limit its use in the clinic. The problem of morphine tolerance has plagued health workers and patients for
Di Cui, Yuanyuan Zhang, Mingyue Zhang
doaj   +1 more source