Results 31 to 40 of about 303,149 (361)

Effect of human mesenchymal stem cell secretome administration on morphine self-administration and relapse in two animal models of opioid dependence

open access: yesTranslational Psychiatry, 2022
The present study investigates the possible therapeutic effects of human mesenchymal stem cell-derived secretome on morphine dependence and relapse. This was studied in a new model of chronic voluntary morphine intake in Wistar rats which shows classic ...
María Elena Quintanilla   +8 more
doaj   +1 more source

Context-dependent effects of the CB1 receptor antagonist rimonabant on morphine-induced behavioral sensitization in female mice

open access: yesFrontiers in Pharmacology, 2023
Introduction: The endocannabinoid system has been implicated in the neurobiology of opioid use disorder. While the CB1 receptor antagonist rimonabant has been shown to block some of the behavioral effects of opioids, studies suggest that the treatment ...
Eduardo A. V. Marinho   +12 more
doaj   +1 more source

Multicentre randomised controlled trial of nasal diamorphine for analgesia in children and teenagers with clinical fractures. [PDF]

open access: yes, 2001
OBJECTIVE: To compare the effectiveness of nasal diamorphine spray with intramuscular morphine for analgesia in children and teenagers with acute pain due to a clinical fracture, and to describe the safety profile of the spray.
Kendall, JM   +3 more
core   +1 more source

Preventing effect of vitamin E on oocytes apoptosis in morphinetreated mice [PDF]

open access: yes, 2013
Several studies have shown that Morphine Sulfate affects on fertility, embryogenesis and consequent pregnancy loss and ultrastructural alterations of oocytes in animal model.
Asadi, E.   +3 more
core   +1 more source

A randomised, controlled, double blind, non-inferiority trial of ultrasound-guided fascia iliaca block vs. spinal morphine for analgesia after primary hip arthroplasty [PDF]

open access: yes, 2016
We performed a single centre, double blind, randomised, controlled, non-inferiority study comparing ultrasound-guided fascia iliaca block with spinal morphine for the primary outcome of 24-h postoperative morphine consumption in patients undergoing ...
Anderson, K.   +7 more
core   +1 more source

Resveratrol reverses morphine-induced neuroinflammation in morphine-tolerant rats by reversal HDAC1 expression

open access: yesJournal of the Formosan Medical Association, 2016
We previously showed that subsequent intrathecal (i.t.) injection of resveratrol (30 μg) significantly reverses morphine-evoked neuroinflammation in morphine-tolerant rats. The present study examined the underlying mechanism.
Ru-Yin Tsai   +4 more
doaj   +1 more source

Acute and chronic effects of morphine on Low-Mg2+ ACSF-induced epileptiform activity during infancy in mice hippocampal slices

open access: yesResearch in Pharmaceutical Sciences, 2019
Interaction of morphine and seizure is complex. Mouse brain hippocampal slices were used to estimate how acute and chronic morphine treatment alters the low-magnesium artificial cerebrospinal fluid (LM-ACSF)-induced seizure activity.
Yousef Panahi   +6 more
doaj   +1 more source

Significance of Metabolite Ratios in the Interpretation of Segmental Hair Testing Results—Differentiation of Single from Chronic Morphine Use in a Case Series

open access: yesMetabolites, 2021
In morphine intoxication cases, forensic toxicologists are frequently confronted with the question of if the individual was opioid-tolerant or opioid-naïve, which can be investigated by hair analysis. However, interpretation of results can be challenging.
Milena M. Madry   +4 more
doaj   +1 more source

PSYCHOSIS OF MORPHINISM. [PDF]

open access: yesJAMA: The Journal of the American Medical Association, 1905
All writers have mentioned the general defective conception of truth and the relation of right and wrong which appears to be a prominent symptom in all persons who use morphia. It is difficult to understand whether this is a veritable paralysis of the higher reasoning centers or a defect of the senses by which distorted conceptions of facts are not ...
openaire   +2 more sources

Amniotic-Fluid Ingestion Enhances\ud Morphine Analgesia During Morphine\ud Tolerance and Withdrawal in Rats [PDF]

open access: yes, 1991
Ingestion of placenta and amniotic fluid has been shown to enhance opioid-mediated analgesia in rats produced by morphine injection. footshock, vaginal/cervical stimulation, and during late pregnancy.
Doerr, Jean C., Kristal, Dr. Mark B.
core  

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