Results 191 to 200 of about 11,589 (292)

Antinociceptive Effect of Cinnamaldehyde in Male Mice: Investigation of the Mechanisms of Action Through In Silico and In Vivo Approaches. [PDF]

Chem Biodivers
Rêgo RIA, Pires HFO, Dias AL, Remigio MCRB, de Andrade HHN, da Silva PR, de Sousa NF, Scotti L, Scotti MT, Salvadori MGSS, de Castro RD.   +10 more
europepmc   +1 more source

Successful replacement of the urinary bladder following exteriorisation during bite‐induced scrotal trauma in a domestic rabbit (Oryctolagus cuniculus)

Veterinary Record Case Reports, Volume 14, Issue 3, August 2026.
Abstract Scrotal exteriorisation of abdominal viscera is rarely reported in domestic rabbits and constitutes a surgical emergency. This report describes traumatic inguinoscrotal herniation of the urinary bladder in a domestic rabbit (Oryctolagus cuniculus), a 4‐month‐old entire male, following bite‐induced scrotal avulsion during territorial aggression.
Delcio Almeida Magalhães, Ana Beatriz Portes Gonçalves, Milena Aimi Taguchi, Maria Jaqueline Mamprim de Arruda Monteiro, Sheila Canevese Rahal   +4 more
wiley   +1 more source

Orofacial antinociceptive effect of a novel 2-amino-thiophene derivative and its possible targets of action. [PDF]

Braz Oral Res
Silva AJD, Silva PRD, Pires HFO, Dias AL, Felipe CFB, Mendonça-Junior FJB, Nayarisseri A, Alves AF, Scotti MT, Golzio AMFO, Castro RD.   +10 more
europepmc   +1 more source

Combination Therapy With Sintilimab and Anlotinib for Advanced Undifferentiated Pleomorphic Sarcoma: A Case Report and Literature Review

Clinical Case Reports, Volume 14, Issue 7, July 2026.
ABSTRACT This report describes the case of a 73‐year‐old woman with advanced undifferentiated pleomorphic sarcoma (UPS) who was intolerant to chemotherapy. Following amputation, she received sintilimab plus anlotinib and achieved a partial response with 76.6% tumor reduction.
Yan Chen, Ronghua Chu
wiley   +1 more source

Pharmacological Studies on Morphine Derivatives. III

YAKUGAKU ZASSHI, 1964
Isao Seki, Hiromu Takagi, Shinsaku Kobayashi   +2 more
openaire   +2 more sources

Visible-light promoted cascade annulation of <i>N</i>-propargylamines with sodium sulfinates to access sulfonylated 9<i>H</i>-pyrrolo[1,2-<i>a</i>]indoles and quinolines. [PDF]

RSC Adv
Wu J, Dong H, Li Z.
europepmc   +1 more source

Patient‐ and Clinician‐Related Factors Associated With the Reduction in Opioid Use Among Adults With Chronic Non‐Cancer Pain: A Systematic Review

Clinical Pharmacology &Therapeutics, Volume 120, Issue 1, Page 66-80, July 2026.
Despite known risks, opioids are widely used for chronic non‐cancer pain (CNCP). Clinical guidelines now recommend deprescribing, but factors predicting success are poorly understood. This systematic review aimed to identify clinician and patient factors associated with attaining successful opioid dose reduction or discontinuation in adults with CNCP ...
Alessandra C. Marcelo, Sarah N. Hilmer, David J. Hunter, Stephanie Mathieson, Riyaas Mohamed, Leo Li, Natalie Fung, Anthony Yue, Manuela L. Ferreira   +8 more
wiley   +1 more source

Structural Determinants of μ-Opioid Receptor Antagonism and Respiratory Liability in Phenylfentanyl Analogues. [PDF]

ACS Chem Neurosci
Li E, Kale BS, Silte AA, Lyu R, Upadhyay N, Neel LT, Reda A, Wang H, Dewey WL, Pagare PP, Zhang Y.   +10 more
europepmc   +1 more source

Integrative Assessment of Desmostachya bipinnata (L.) Root Extract: Anti‐Inflammatory and Antinociceptive Effects Supported by Molecular Docking and Network Pharmacology

Flavour and Fragrance Journal, Volume 41, Issue 4, Page 841-858, July 2026.
The ethanolic root extract of Desmostachya bipinnata exhibited significant anti‐inflammatory and antinociceptive activities in in vitro, in vivo and in silico models, revealing bioactive compounds capable of modulating key inflammatory targets and supporting the plant's traditional therapeutic potential.
Muhammad Hussnain Siddique, Muhammad Muzammil Nazir, Saima Muzammil, Iqra Farzeen, Shafaq Latif, Asma Ashraf, Jorddy Neves Cruz   +6 more
wiley   +1 more source

Discovery of a Colon-Targeted Prodrug As an <i>Escherichia coli</i> Biofilm Inhibitor for Treating Inflammatory Bowel Disease. [PDF]

ACS Med Chem Lett
Shimizu T, Tago K, Yokoyama M, Nakamura K, Tokieda-Tanoue S, Kita A, Miyazaki S.   +6 more
europepmc   +1 more source