Results 1 to 10 of about 21,395 (260)
Zinc chloride-catalyzed cyclizative 1,2-rearrangement enables facile access to morpholinones bearing aza-quaternary carbons [PDF]
Communications Chemistry, 2023 Morpholines and morpholinones are important building blocks in organic synthesis and pharmacophores in medicinal chemistry, however, C3-disubstituted morpholines/morpholinones are extremely difficult to access.
Xing-Zi Li, Yu-Ping He, Hua Wu
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Morpholin-4-ium morpholine-4-carbodithioate [PDF]
Acta Crystallographica Section E Structure Reports Online, 2011 The title compound, C(4)H(10)NO(+)·C(5)H(8)NOS(2) (-), is built up of a morpholinium cation and a dithio-carbamate anion. In the crystal, two structurally independent formula units are linked via N-H⋯S hydrogen bonds, forming an inversion dimer, with graph-set motif R(4) (4)(12).
Maria Teresa do Prado Gambardella +2 more
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Structures of piperazine, piperidine and morpholine [PDF]
Acta Crystallographica Section B Structural Science, 2004 The crystal structures of piperazine, piperidine and morpholine have been determined at 150 K. All three structures are characterized by the formation of NH...N hydrogen-bonded chains. In piperazine these are linked to form sheets, but the chains are shifted so that the molecules interleave. In morpholine there are in addition weak CH...O interactions.
Parkin, A, Oswald, I D H, Parsons, S
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Synthesis and antimicrobial activity of 4-(5-ARYL-2-FUROYL)morpholines and 4-[(5-ARYL-2-FURYL)carbonothioyl] morpholines [PDF]
Pharmacia, 2021 By the reaction of furan-2-carboxylic acids and furfural with diazonium salts 1a-j the arylfuran-2-carboxylic acids 4a-e and 5-arylfuran-2-carbaldehydes 5a-f were synthesized. Acids 4a-e were transformed into appropriated acylchlorides 6a-e and were used
Yuliia Matiichuk +6 more
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Comparative assessment of stability of fungicides triazolopyrimidine, triazole, pyrimidine and morpholine in the soil and prediction of groundwater pollution with them. [PDF]
Medičnì Perspektivi, 2016 The purpose of our study was prediction of ground water contamination with fungicides of different chemical classes in soil-climatic conditions of Ukraine and other European countries and hygienic assessment of their harmful effects on human health.
S. V. Bіlous +3 more
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Chronic morpholine exposure of rats [PDF]
Fundamental and Applied Toxicology, 1989 The chronic toxicity and carcinogenic potential of morpholine were evaluated in 60 Sprague-Dawley rats/sex/group receiving morpholine at mean inhalation exposure concentrations of 0, 10, 50 and 150 ppm for 6 hr/day, 5 days/week, for 104 weeks. Survival, body weight gains, organ weights, hematology, and clinical chemistries were normal in exposed groups
Center for Environmental Toxicology, University of Florida, Alachua, Florida 32615 USA ( host institution ) +5 more
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Acta Chimica Slovenica, 2022 The studies on nitronaphthoquinone derivatives are rare in the literature, and the nitro group associated with the aromatic ring in the quinone system is known to increase the biological activity of naphthoquinone due to its electron-withdrawing ...
Aesha FSH Abdassalam +5 more
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Current Research in Toxicology, 2022 The cardiac embryonic stem cell test (ESTc) is a well-studied non-animal alternative test method based on cardiac cell differentiation inhibition as a measure for developmental toxicity of tested chemicals.
R.H. Mennen +5 more
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Candidiasis and Mechanisms of Antifungal Resistance
Antibiotics, 2020 Candidiasis can be present as a cutaneous, mucosal or deep-seated organ infection, which is caused by more than 20 types of Candida sp., with C. albicans being the most common.
Somanon Bhattacharya +2 more
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PKC signaling regulates drug resistance of the fungal pathogen Candida albicans via circuitry comprised of Mkc1, calcineurin, and Hsp90. [PDF]
PLoS Pathogens, 2010 Fungal pathogens exploit diverse mechanisms to survive exposure to antifungal drugs. This poses concern given the limited number of clinically useful antifungals and the growing population of immunocompromised individuals vulnerable to life-threatening ...
Shantelle L LaFayette +7 more
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