Results 21 to 30 of about 18,857 (217)

New Strategy for the Synthesis of Morpholine Cores: Synthesis from N-Propargylamines [PDF]

Iranian Journal of Chemistry & Chemical Engineering, 2017
Functionalized morpholines have attracted much attention due to their potential biological activities. Despite the wide importance of morpholine derivatives in drug design of various pharmacological agents, the development of new approaches to their ...
Esmail Vessally, Akram Hosseinian, Ladan Edjlali, Mirzaagha Babazadeh, Rahim Hosseinzadeh-Khanmiri   +4 more
doaj  

Structure Prediction and Functional Characterization of ERG Proteins Involved in Ergosterol Biosynthetic Pathway of Candida albicans [PDF]

, 2011
The ERG proteins and enzymes of the ergosterol biosynthetic pathway has been the subject of intensive investigation as a target for several classes of antifungal agents used to treat C. albicans infection. Over the past few decades, a number of drugs and
Ashok Sharma, Suaib Luqman, Sudeep Roy   +2 more
core   +2 more sources

Strategies Toward Accessing Enantioenriched (Hetero)Benzo‐Fused 5‐ and 6‐ Membered Rings via Intermolecular Carbometalation

Angewandte Chemie, EarlyView.
The use of transition‐metal catalysts and design of chiral ligands have allowed chemists to access highly functionalized benzofused 5‐ and 6‐ membered rings in high yield and enantioselectivity. A common strategy used relies on an intermolecular carbometalation across alkynes and olefins, usually followed by a subsequent intramolecular carbometalation.
Clara Jans, Armaan Grewal, Xavier Abel‐Snape, Mark Lautens   +3 more
wiley   +2 more sources

Metal-free one-pot synthesis of 2-substituted and 2,3-disubstituted morpholines from aziridines

Beilstein Journal of Organic Chemistry, 2015
The metal-free synthesis of 2-substituted and 2,3-disubstituted morpholines through a one-pot strategy is described. A simple and inexpensive ammonium persulfate salt enables the reaction of aziridines with halogenated alcohols to proceed via an SN2-type
Hongnan Sun, Binbin Huang, Run Lin, Chao Yang, Wujiong Xia   +4 more
doaj   +1 more source

Crystal structure of 3-(morpholin-4-yl)-1-phenyl-3-(pyridin-2-yl)propan-1-one [PDF]

, 2014
Acknowledgements FMMA acknowledges the PG and Research Department of Chemistry and the Management of Jamal Mohamed College (Autonomous) for their kind support.Peer reviewedPublisher ...
Ahamed, F M M, Gunasekaran, B., Padusha, M S A   +2 more
core   +2 more sources

Ultrasonicated Synthesis of N-Benzyl-2,3-substituted Morpholines, via the Mitsunobu Diol Cyclisation

E-Journal of Chemistry, 2010
A facile five step synthesis of N-benzyl-2,3-substituted morpholines (i-iii) was performed. The key steps were microwave assisted Friedel-crafts acylation and diol cyclization carried out via an ultra sonication of Mitsunobu reaction using DEAD ...
B. Jayachandra Reddy, M. C. Somasekhara Reddy   +1 more
doaj   +1 more source

Determination of antimicrobial activity of some 1,2,4-triazole derivatives

Regulatory Mechanisms in Biosystems, 2018
We carried out MIC of the derivatives of 1,2,4-triazole II (4-((5-nitrofuran-2-yl)methyleneamino)-1-propyl-4H-1,2,4-triazolium bromide) and I (N-((5-nitrofuran-2-yl)methylene)-4H-4-amino-1,2,4-triazolidium chloride) against Escherichia coli ATCC 3912/4 ...
M. S. M. Alrawashdeh
doaj   +1 more source

Widespread contamination of wildflower and bee-collected pollen with complex mixtures of neonicotinoids and fungicides commonly applied to crops [PDF]

, 2016
There is considerable and ongoing debate as to the harm inflicted on bees by exposure to agricultural pesticides. In part, the lack of consensus reflects a shortage of information on field-realistic levels of exposure. Here, we quantify concentrations of
Artz, Beekman, Bingham, Bonmatin, Botías, Carreck, Cresswell, Cresswell, David, Demske, du Rand, Dussaubat, Fairbrother, Goulson, Goulson, Goulson, Gupta, Heinrich, Human, Iwasa, Johnson, Johnson, Khan, Kirk, Knight, Lambert, Moore, Mullin, Mullin, Osborne, Rundlöf, Sanchez-Bayo, Sawyer, Schmuck, Suchail, Thompson, Whitehorn, Wood, Yoder, Yoder, Zhu   +40 more
core   +1 more source

Vacuolar H+-Pyrophosphatase AVP1 is Involved in Amine Fungicide Tolerance in Arabidopsis thaliana and Provides Tridemorph Resistance in Yeast [PDF]

, 2016
Amine fungicides are widely used as crop protectants. Their success is believed to be related to their ability to inhibit postlanosterol sterol biosynthesis in fungi, in particular sterol-Δ8,Δ7-isomerases and sterol-Δ14-reductases, with a concomitant ...
Agustín eHernández, Agustín eHernández, Aurelio eSerrano, Federico eValverde, Guillermo eLopez-Lluch, Jose Roman Perez-Castiñeira, Juan Manuel Madroñal, Plácido eNavas, Rosana eHerrera-Palau, Tomás eAlbi   +9 more
core   +1 more source

Morpholine

The German Senate Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area (MAK Commission) has re-evaluated the occupational exposure limit value (maximum concentration at the workplace, MAK value) and the pregnancy risk group of morpholine [110-91-8] considering also irritating and sensitizing effects.
Hartwig, Andrea, MAK Commission, Arand, Michael   +2 more
  +4 more sources