Results 11 to 20 of about 18,579 (227)

Metal-free one-pot synthesis of 2-substituted and 2,3-disubstituted morpholines from aziridines

Beilstein Journal of Organic Chemistry, 2015
The metal-free synthesis of 2-substituted and 2,3-disubstituted morpholines through a one-pot strategy is described. A simple and inexpensive ammonium persulfate salt enables the reaction of aziridines with halogenated alcohols to proceed via an SN2-type
Hongnan Sun, Binbin Huang, Run Lin, Chao Yang, Wujiong Xia   +4 more
doaj   +2 more sources

Expanding Complex Morpholines Using Systematic Chemical Diversity. [PDF]

Org Lett
The morpholine heterocycle is a structural unit found in many bioactive compounds and FDA-approved drugs, but the generation of more complex C-functionalized morpholine derivatives remains considerably underexplored.
Tang SA, Fults A, Boyd SR, Gattu N, Tran KA, Fan J, MacKenzie KR, Palzkill T, Young DW, Chamakuri S.   +9 more
europepmc   +3 more sources

Flexible access to conformationally-locked bicyclic morpholines [PDF]

, 2013
A preparatively accessible route to a series of conformationally-locked bicyclic morpholines has been developed. This flexible approach allows for diversification in order for a small array of lead-like scaffolds to be synthesised from readily available ...
Lamont, Scott, Paterson, Laura C., Parkinson, John A., Kerr, W. J., Bogacki, Rachael, Gill, Duncan M.   +5 more
core   +4 more sources

Application of the morpholines of 2 - [5 - (pyridin-4-yl) -1,2,4-triazol-3-ylthio] acetates for the treatment and prevention of some diseases

Zaporožskij Medicinskij Žurnal, 2014
Range of applications of morpholines of 2-[5-(pyridin-4-yl)-1,2,4-triazol-3-ylthio] acetate for treatment and prevention of birds diseases is very wide.
I. V. Bushueva, L. I. Parkhomenko, E. G. Knish, O. I. Panasenko   +3 more
doaj   +1 more source

Practical Synthesis of Enantiomerically Pure Morpholines

, 2008
Recent advances towards the synthesis of enantiomerically pure substituted morpholines are ...
E. Carlini, D. Albanese, F. Foschi, M. Penso, A. Tagliabue   +4 more
core   +3 more sources

Electrochemical Synthesis of Substituted Morpholines via a Decarboxylative Intramolecular Etherification

, 2022
An efficient method for the synthesis of 2,6-multisubstituted morpholines via an electrochemical intramolecular etherification has been developed. The method, which is operationally simple and easy to scale up, provides various substituted morpholine ...
Komei Sakata, Takahiro Yamada (28667), Takahiro Yamada, Ryosuke Yamada (704324), Ryosuke Yamada, Komei Sakata (1971703)   +5 more
core   +1 more source

The Synthesis and Biological Activity of 1-Alkyl-4-(3-azacyclobenzoyl)-5-hydroxypyrazole Herbicides

CHIMIA, 2003
The benzoylpyrazoles belong to a class of herbicides that inhibit the enzyme 4-hydroxy-phenylpyruvate dioxygenase (HPPD). This mode of action is characterized by bleaching due to the disruption of plastoquinone and ?-tocopherol biosynthesis ...
Zoltan Benko, Sharon Shinkle, John Van Heertum, Johnny Jackson, Jeffery McQuiston, Jeffery Webster, James Turner, Monte Weimer, Eileen Paterson   +8 more
doaj   +1 more source

Nouvelles exploitations des tétrazoles comme précurseurs en synthèse organique: accès aux morpholines, cyanamides et produits naturels [PDF]

, 2021
Les cycles azotés font partie intégrante de la vie sur Terre. Cette thématique est transcrite dans les travaux de cette thèse à travers les tétrazoles et les morpholines.
Duchamp, Edouard
core   +1 more source

Synthèse d'hétérocycles azotés : tétrahydropyrazines et morpholines [PDF]

, 2018
Tetrahydropyrazines and morpholines are six-membered heterocycles including two heteroatoms in positions 1 and 4. The objectives of this thesis were to develop new methods for their synthesis.
Aubineau, Thomas
core   +1 more source

New Strategy for the Synthesis of Morpholine Cores: Synthesis from N-Propargylamines [PDF]

Iranian Journal of Chemistry & Chemical Engineering, 2017
Functionalized morpholines have attracted much attention due to their potential biological activities. Despite the wide importance of morpholine derivatives in drug design of various pharmacological agents, the development of new approaches to their ...
Esmail Vessally, Akram Hosseinian, Ladan Edjlali, Mirzaagha Babazadeh, Rahim Hosseinzadeh-Khanmiri   +4 more
doaj