Results 11 to 20 of about 17,730 (182)

The Synthesis and Biological Activity of 1-Alkyl-4-(3-azacyclobenzoyl)-5-hydroxypyrazole Herbicides

CHIMIA, 2003
The benzoylpyrazoles belong to a class of herbicides that inhibit the enzyme 4-hydroxy-phenylpyruvate dioxygenase (HPPD). This mode of action is characterized by bleaching due to the disruption of plastoquinone and ?-tocopherol biosynthesis ...
Zoltan Benko, Sharon Shinkle, John Van Heertum, Johnny Jackson, Jeffery McQuiston, Jeffery Webster, James Turner, Monte Weimer, Eileen Paterson   +8 more
doaj   +1 more source

New Strategy for the Synthesis of Morpholine Cores: Synthesis from N-Propargylamines [PDF]

Iranian Journal of Chemistry & Chemical Engineering, 2017
Functionalized morpholines have attracted much attention due to their potential biological activities. Despite the wide importance of morpholine derivatives in drug design of various pharmacological agents, the development of new approaches to their ...
Esmail Vessally, Akram Hosseinian, Ladan Edjlali, Mirzaagha Babazadeh, Rahim Hosseinzadeh-Khanmiri   +4 more
doaj  

Metal-free one-pot synthesis of 2-substituted and 2,3-disubstituted morpholines from aziridines

Beilstein Journal of Organic Chemistry, 2015
The metal-free synthesis of 2-substituted and 2,3-disubstituted morpholines through a one-pot strategy is described. A simple and inexpensive ammonium persulfate salt enables the reaction of aziridines with halogenated alcohols to proceed via an SN2-type
Hongnan Sun, Binbin Huang, Run Lin, Chao Yang, Wujiong Xia   +4 more
doaj   +1 more source

Ultrasonicated Synthesis of N-Benzyl-2,3-substituted Morpholines, via the Mitsunobu Diol Cyclisation

E-Journal of Chemistry, 2010
A facile five step synthesis of N-benzyl-2,3-substituted morpholines (i-iii) was performed. The key steps were microwave assisted Friedel-crafts acylation and diol cyclization carried out via an ultra sonication of Mitsunobu reaction using DEAD ...
B. Jayachandra Reddy, M. C. Somasekhara Reddy   +1 more
doaj   +1 more source

Determination of antimicrobial activity of some 1,2,4-triazole derivatives

Regulatory Mechanisms in Biosystems, 2018
We carried out MIC of the derivatives of 1,2,4-triazole II (4-((5-nitrofuran-2-yl)methyleneamino)-1-propyl-4H-1,2,4-triazolium bromide) and I (N-((5-nitrofuran-2-yl)methylene)-4H-4-amino-1,2,4-triazolidium chloride) against Escherichia coli ATCC 3912/4 ...
M. S. M. Alrawashdeh
doaj   +1 more source

Morpholine

The German Senate Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area (MAK Commission) has re-evaluated the occupational exposure limit value (maximum concentration at the workplace, MAK value) and the pregnancy risk group of morpholine [110-91-8] considering also irritating and sensitizing effects.
Hartwig, Andrea, MAK Commission, Arand, Michael   +2 more
  +4 more sources

A Novel Class of “Super‐Strained” Spiro Heterocycles: Gateway to 1‐Azaspiro[3.3]heptane Derivatives, and Biological Validation

Angewandte Chemie, EarlyView.
A new class of “super‐strained” spiro heterocycles—spirocyclic 1‐azabicyclo[1.1.0]butanes—was synthesized via insertion of cyclobutane‐, oxetane‐, and azetidine‐containing sulfonium reagents into substituted azirines. The stability of this new class of compounds was studied.
Philipp Natho, Annarita Vicenti, Marco Colella, Francesco Pasca, Giuseppe Romanazzi, Mauro Niso, Carmen Abate, Ernesto Mesto, Emanuela Schingaro, Renzo Luisi   +9 more
wiley   +2 more sources

Speciation‐Controlled C–F Bond Functionalization Enabled by Zwitterionic Pnictinidenes

Angewandte Chemie, EarlyView.
Zwitterionic pnictinidenes turn C–F activation into C–X bond construction, enabling broad defluorinative functionalization of polyfluoro(hetero)arenes under mild conditions. Rather than following a metallomimetic Sb(I)/Sb(III) redox turnover, catalysis is redirected by ligand scrambling into a redox‐neutral manifold, revealing catalyst speciation as a ...
Irene Sánchez‐Sordo, Sergio Fernandez, Selwin Fernando, Diego M. Andrada, Oriol Planas   +4 more
wiley   +2 more sources

Molecularly Templated Buried Interfaces for Inverted Perovskite Solar Cells

Angewandte Chemie, EarlyView.
We demonstrate a molecularly matched buried interface between SAM and perovskite, enhancing adhesion and passivating defects. This optimized interface achieves 26.58% power conversion efficiency and 86.72% fill factor with exceptional operational stability in both large‐area and wide‐bandgap devices, thereby increasing efficiency and prolonging ...
Songyang Yuan, Quanrun Qiu, Huaiman Cao, Chengda Ge, Yiting Jiang, Gengyang Su, Lingyi Ke, Gengxin Du, Guangruixing Zou, Hui Liu, Guanhua Ren, Jing Wang, Nan Zhang, Yidan An, Qingduan Li, Ze Yu, Tao Jia, Yue‐Peng Cai, Shengjian Liu, Hin‐Lap Yip   +19 more
wiley   +2 more sources

Borylcyclopropanes: Synthetic Strategies and Applications

Angewandte Chemie, EarlyView.
Borylcyclopropanes (cyclopropanes bearing a boron substituent) sit at the intersection of two privileged frameworks in synthesis. This review provides the first exhaustive survey of their chemistry, spanning metal–carbene, nucleophilic cyclization, radical, hydroboration, and C─H activation routes, and documenting applications in medicinal chemistry ...
Aiza A. Butt, Joseph M. Ready
wiley   +2 more sources