Results 11 to 20 of about 18,532 (197)
Candidiasis and Mechanisms of Antifungal Resistance
Antibiotics, 2020 Candidiasis can be present as a cutaneous, mucosal or deep-seated organ infection, which is caused by more than 20 types of Candida sp., with C. albicans being the most common.
Somanon Bhattacharya +2 more
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PKC signaling regulates drug resistance of the fungal pathogen Candida albicans via circuitry comprised of Mkc1, calcineurin, and Hsp90. [PDF]
PLoS Pathogens, 2010 Fungal pathogens exploit diverse mechanisms to survive exposure to antifungal drugs. This poses concern given the limited number of clinically useful antifungals and the growing population of immunocompromised individuals vulnerable to life-threatening ...
Shantelle L LaFayette +7 more
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, 2022 An efficient method for the synthesis of 2,6-multisubstituted morpholines via an electrochemical intramolecular etherification has been developed. The method, which is operationally simple and easy to scale up, provides various substituted morpholine ...
Komei Sakata +5 more
core +1 more source
Practical synthesis of enantiomerically pure morpholines
, 2008 Recent advances towards the synthesis of enantiomerically pure substituted morpholines are ...
Penso M +4 more
core +3 more sources
Molecules, 2017 The aim of this study was to investigate acetylcholinesterase (AChE), monoamine oxidase A (MAO-A), monoamine oxidase B (MAO-B), cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) enzyme inhibitory, and antimicrobial activities of a new series of 2-(4 ...
Nafiz Öncü Can +7 more
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, 2021 Scheme Synthesis of 4-(5-aryl-2-furoyl)morpholines and 4-[(5-aryl-2-furyl)carbonothioyl ...
Matiichuk, Yuliia +13 more
core +1 more source
Zaporožskij Medicinskij Žurnal, 2014 Range of applications of morpholines of 2-[5-(pyridin-4-yl)-1,2,4-triazol-3-ylthio] acetate for treatment and prevention of birds diseases is very wide.
I. V. Bushueva +3 more
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The Synthesis and Biological Activity of 1-Alkyl-4-(3-azacyclobenzoyl)-5-hydroxypyrazole Herbicides
CHIMIA, 2003 The benzoylpyrazoles belong to a class of herbicides that inhibit the enzyme 4-hydroxy-phenylpyruvate dioxygenase (HPPD). This mode of action is characterized by bleaching due to the disruption of plastoquinone and ?-tocopherol biosynthesis ...
Zoltan Benko +8 more
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SnAP Reagents for the Synthesis of Piperazines and Morpholines
, 2016 Substituted piperazines and morpholines are valuable structural motifs in biologically active compounds, but are not easily prepared by contemporary cross-coupling approaches. In this report, we introduce SnAP reagents for the transformation of aldehydes
Cam-Van T. Vo (1843522) +2 more
core +2 more sources
New Strategy for the Synthesis of Morpholine Cores: Synthesis from N-Propargylamines [PDF]
Iranian Journal of Chemistry & Chemical Engineering, 2017 Functionalized morpholines have attracted much attention due to their potential biological activities. Despite the wide importance of morpholine derivatives in drug design of various pharmacological agents, the development of new approaches to their ...
Esmail Vessally +4 more
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