Morpholine-Facilitated Enrichment-Triggered Delivery of Carbon Monoxide to Lysosome: A Feasibility Study. [PDF]
Tripathi R +6 more
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Oseltamivir and baloxavir monotherapy and combination therapy efficacy against clade 2.3.4.4b A(H5N1) influenza virus infection in ferrets. [PDF]
Belser JA +9 more
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Efficacy of baloxavir marboxil against bovine H5N1 virus in mice. [PDF]
Kiso M, Uraki R, Yamayoshi S, Kawaoka Y.
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Structure-activity relationship of GSK-3β inhibitors: insight into drug design for Alzheimer's disease. [PDF]
Rajamani G, Naqvi S, Sharma A.
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Drug repurposing of fostamatinib against cancer via potential cytotoxicity and immune checkpoint regulation. [PDF]
Hu M, Yin R, Deng K, Xu N.
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Susceptibility of Neisseria gonorrhoeae to Zoliflodacin and Quinolones in Hyogo Prefecture, Japan. [PDF]
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New strategies for the enantioselective synthesis of morpholines and β-hydroxy-α-amino acids [PDF]
Sladojevich, Filippo
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Comparison of Esmolol Versus Landiolol on Mortality in Adult Patients With Sepsis: A Systematic Review and Network Meta-Analysis. [PDF]
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Aminomethylation of Imidazoheterocycles with Morpholine
Organic Letters, 2017A hitherto unreported aminomethylation occurs at C-3 of imidazopyridines with morpholine in the presence of (diacetoxyiodo)benzene at ambient temperature in short reaction times. This methodology is also applicable to indolizine, imidazo[2,1-b]thiazole, benzo[d]imidazo[2,1-b]thiazole, and indole. Interestingly, the aminomethylation involving morpholine
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In the title compound, C4H5NO3, the morpholine ring adopts a boat conformation that is distorted towards twist-boat, the boat ends being the two Csp3 atoms of the ring. The molecular packing is stabilized by the establishment of strong intermolecular NH...OC hydrogen bonds, which give rise to centrosymmetric dimers, and a network of weak CH2...OC ...
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