Results 11 to 20 of about 21,395 (260)

Heterocyclic Merging of Stereochemically Diverse Chiral Piperazines and Morpholines with Indazoles. [PDF]

Chemistry, 2023
We report a heterocyclic merging approach to construct novel indazolo-piperazines and indazolo-morpholines. Starting from chiral diamines and amino alcohols, novel regiochemically (1,3 and 1,4) and stereochemically diverse (relative and absolute) cohorts
Viveki AB, Mansfield TM, Tran KA, Lenkeit E, MacKenzie KR, Young DW, Chamakuri S.   +6 more
europepmc   +3 more sources

Genomic Surveillance and Molecular Evolution of Fungicide Resistance in European Populations of Wheat Powdery Mildew. [PDF]

Mol Plant Pathol
Fungicides are used in agriculture to manage fungal infections and maintain crop yield and quality. In Europe, their application on cereals increased drastically starting from the mid 1970s, contributing to a significant improvement in yields.
Minadakis N, Jigisha J, Cornetti L, Kunz L, Müller MC, Torriani SFF, Menardo F.   +6 more
europepmc   +3 more sources

Flexible access to conformationally-locked bicyclic morpholines [PDF]

, 2013
A preparatively accessible route to a series of conformationally-locked bicyclic morpholines has been developed. This flexible approach allows for diversification in order for a small array of lead-like scaffolds to be synthesised from readily available ...
Brawn, Brice, Chen, Dow, Duncan M. Gill, Furber, Garrison, Ito, John A. Parkinson, Kilonda, Laura C. Paterson, Long, MacLellan, Rachael Bogacki, Sayago, Scott Lamont, Smith, Still, Timmer, William J. Kerr, Xiao   +20 more
core   +1 more source

Pharmacological and Toxicological Screening of Novel Benzimidazole-Morpholine Derivatives as Dual-Acting Inhibitors

Molecules, 2017
The aim of this study was to investigate acetylcholinesterase (AChE), monoamine oxidase A (MAO-A), monoamine oxidase B (MAO-B), cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) enzyme inhibitory, and antimicrobial activities of a new series of 2-(4 ...
Nafiz Öncü Can, Ulviye Acar Çevik, Begüm Nurpelin Sağlık, Yusuf Özkay, Özlem Atlı, Merve Baysal, Ümide Demir Özkay, Özgür Devrim Can   +7 more
doaj   +1 more source

Application of the morpholines of 2 - [5 - (pyridin-4-yl) -1,2,4-triazol-3-ylthio] acetates for the treatment and prevention of some diseases

Zaporožskij Medicinskij Žurnal, 2014
Range of applications of morpholines of 2-[5-(pyridin-4-yl)-1,2,4-triazol-3-ylthio] acetate for treatment and prevention of birds diseases is very wide.
I. V. Bushueva, L. I. Parkhomenko, E. G. Knish, O. I. Panasenko   +3 more
doaj   +1 more source

Yield and disease control in winter wheat in southern Sweden during 1977-2005 [PDF]

, 2009
Fungicides are routinely used to prevent yield losses in winter wheat in southern Sweden. Yield and 1000 grain weight (TGW) data from 432 trials in farmers’ fields were evaluated to review long-term yields (1977-2005) and control of eyespot and Leaf ...
Wiik, Lars
core   +1 more source

Crystal structure of 3-(morpholin-4-yl)-1-phenyl-3-(pyridin-2-yl)propan-1-one [PDF]

, 2014
Acknowledgements FMMA acknowledges the PG and Research Department of Chemistry and the Management of Jamal Mohamed College (Autonomous) for their kind support.Peer reviewedPublisher ...
Ahamed, F M M, Gunasekaran, B., Padusha, M S A   +2 more
core   +2 more sources

The Synthesis and Biological Activity of 1-Alkyl-4-(3-azacyclobenzoyl)-5-hydroxypyrazole Herbicides

CHIMIA, 2003
The benzoylpyrazoles belong to a class of herbicides that inhibit the enzyme 4-hydroxy-phenylpyruvate dioxygenase (HPPD). This mode of action is characterized by bleaching due to the disruption of plastoquinone and ?-tocopherol biosynthesis ...
Zoltan Benko, Sharon Shinkle, John Van Heertum, Johnny Jackson, Jeffery McQuiston, Jeffery Webster, James Turner, Monte Weimer, Eileen Paterson   +8 more
doaj   +1 more source

A paracetamol–morpholine adduct

Acta Crystallographica Section E Structure Reports Online, 2002
Paracetamol [also known as acet­amino­phen or N-(4-hydroxy­phenyl)­acet­amide] is an important analgesic drug that has recently been cocrystallized with a series of cyclic N- and O-donor compounds. This paper describes the formation of a paracetamol adduct with morpholine, viz. paracetamol–morpholine (1/2.5), C8H9NO2·2.5C4H9NO.
Oswald, I D H, Motherwell, W D S, Parsons, S, Pulham, C R   +3 more
openaire   +3 more sources

Optimisation of a Key Cross-Coupling Reaction Towards the Synthesis of a Promising Antileishmanial Compound [PDF]

, 2019
During the course of a research program aimed at identifying novel antileishmanial compounds, a multi-gram synthesis of N-(trans-4-((4-methoxy-3-((R)-3-methylmorpholino)-1H-pyrazolo[3,4-d]pyrimidin-6-yl)amino)cyclohexyl)-2-methylpropane-1-sulfonamide ((R)
Fra, Gloria, Gilbert, Ian H., Guerrero, César, Miguel-Siles, Juan, Miles, Timothy J., Moure, Alejandra, Quesada-Campos, Maria Teresa, Ruiz-Gomez, Jose Ramon, Thomas, Michael G., Velasco, Raul F.   +9 more
core   +2 more sources