Results 71 to 80 of about 21,395 (260)
ChemistryEurope, EarlyView.A structurally engineered nonviral vector (poly (β‐amino esters)‐lipid‐palmitic anhydride nanoparticles) integrates a poly(β‐amino ester) core for mRNA binding, palmitic anhydride for enhancing cellular uptake, and cationic 1,2‐Dioleoyl‐3‐trimethylammonium‐propane lipid for endosomal disruption is developed, which achieves 64.4% transfection efficiency
Zheng Wang +8 more
wiley +1 more source
ChemistryEurope, EarlyView.GA: Sulfonimidoyl fluorides react with a diverse set of amines in a HOBt‐catalyzed sulfur(VI) fluorine exchange reaction to access sulfonimidamides, including directly NH‐sulfonimidamides, and in an automated workflow. In addition, SNAr reactivity of 4‐fluoroaryl sulfonimidoyl fluorides is discovered and exploited to prepare complex sulfonimidoyl ...
Dominique Deans +6 more
wiley +1 more source
Enantioselective Desymmetrization by Chiral Bifunctional H‐Bonding Organocatalysts
Chemistry – A European Journal, EarlyView.Enantioselective desymmetrization has emerged as a highly efficient and conceptually elegant strategy for the construction of chiral molecules from readily available prochiral substrates. This review focuses on recent developments in organocatalytic desymmetrization reactions, with particular emphasis on approaches involving bifunctional activation ...
Michal Urban, Jan Veselý
wiley +1 more source
Chemistry – A European Journal, EarlyView.Use of N‐heterocyclic carbenes (NHCs) to activate carbon and heteroatoms in aromatic compounds is reviewed based on key dearomative NHC‐bound intermediates, i.e., ortho‐quinodimethanes (o‐QDMs), ortho‐quinone methides (o‐QMs) and aza‐analogs (aza‐o‐QMs), aza‐fulvene and triaza‐diene intermediates.
Carmela De Risi +4 more
wiley +1 more source
Is environmentally-friendly agriculture less profitable for farmers ? evidence on integrated pest management in Bangladesh [PDF]
Concerns about the sustainability of conventional agriculture have prompted widespread introduction of integrated pest management (IPM), an ecologically-based approach to control of harmful insects and weeds.
Dasgupta, Susmita +2 more
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Deuteration of Six‐Membered N‐Heteroarenes: Chemistry and Applications
Chemistry – A European Journal, EarlyView.Deuterated six‐membered N‐Heteroarenes (6NHetAr) are finding utility in an increasing repertoire of applications. Our paper comprehensively reviews synthetic approaches that have been reported for the deuteration of 6NHetAr and their fused counterparts while providing an overview of established and emerging applications for these materials.
Liju Raju +4 more
wiley +1 more source
Versatile Palladium‐Catalyzed C‐H Arylation of Fluoroarenes with 2‐Chloropyridine Derivatives
Chemistry – A European Journal, EarlyView.Direct C─H arylation of fluoroarenes with 2‐chloropyridines is enabled by a simple Pd/SPhos system in isopropyl acetate. The method uses inexpensive reactants and shows broad scope and high yields. DFT computations explain reactivity and selectivity.
Federico Belnome +6 more
wiley +1 more source
Innovations sociales pour éliminer les pesticides dans les bananeraies : les conditions de mobilisation du travail [PDF]
, 2010 Les déterminants des changements technologiques (techniques et organisationnels) renvoient à des effets de taille des entreprises, de structuration des marchés.
Temple, Ludovic
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Pharmaceuticals Made with Hydrogen: A Sustainable and Efficient Approach Using Flow Synthesis
Chemistry – A European Journal, EarlyView.We demonstrate a sustainable strategy for pharmaceutical manufacturing by combining hydrogen, heterogeneous catalysis, and continuous flow synthesis. The development of novel catalysts and their application in a multi‐step synthesis of donepezil enabled a highly productive process with no intermediate purification.
Shū Kobayashi, Haruro Ishitani
wiley +1 more source
Molecular Docking and Target‐Specific Binding Profiles of Benzosuberane‐Based Compounds
ChemMedChem, EarlyView.Benzosuberane represents a promising scaffold in medicinal chemistry. Several benzosuberane‐based derivatives are described in this review as anticancer agents, including antivascular agents, DNA‐intercalators, receptor modulators and kinase inhibitors.
Michail A. Saragatsis +3 more
wiley +1 more source