Results 91 to 100 of about 6,593,494 (394)

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

Influence of nitrogen and phosphorous on the growth and root morphology of Acer mono

open access: yesPLoS ONE, 2017
Nitrogen and phosphorous are critical determinants of plant growth and productivity, and both plant growth and root morphology are important parameters for evaluating the effects of supplied nutrients. Previous work has shown that the growth of Acer mono
M. Razaq   +3 more
semanticscholar   +1 more source

miRNAs as Influencers of Cell–Cell Communication in Tumor Microenvironment

open access: yesCells, 2020
microRNAs (miRNAs) are small noncoding RNAs that regulate gene expression at the posttranscriptional level, inducing the degradation of the target mRNA or translational repression.
Ilaria Conti   +6 more
doaj   +1 more source

Hydrological Interpretation of Basin Morphology [PDF]

open access: yes, 1978
Completion Report OWRT Agreement No. 14-31-0001-5002 OWRT Project A-049-ALASHydrologic processes in a particular basin are governed by three groups of factors: input regimes of mass and energy, the nature of mass and energy transfer and ...
Fox, John D.
core  

Quantification of MagLIF morphology using the Mallat Scattering Transformation

open access: yes, 2020
The morphology of the stagnated plasma resulting from Magnetized Liner Inertial Fusion (MagLIF) is measured by imaging the self-emission x-rays coming from the multi-keV plasma.
Ampleford, David J.   +9 more
core   +1 more source

Advances in Morphological Theory: Construction Morphology and Relational Morphology

open access: yesAnnual Review of Linguistics, 2022
In recent years, construction-based approaches to morphology have gained ground in the research community. This framework is characterized by the assumption that the mental lexicon is extensive and richly structured, containing not only a large number of stored words but also a wide variety of generalizations in the form of schemas.
openaire   +2 more sources

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Suppression of GRK2 expression reduces endothelial dysfunction by restoring glucose homeostasis

open access: yesScientific Reports, 2017
Despite the associations between diabetic complications and vascular endothelial dysfunction, a direct therapeutic method targeting endothelial dysfunction remains poorly characterized.
Kumiko Taguchi   +5 more
doaj   +1 more source

3D printed spermathecae as experimental models to understand sperm dynamics in leaf beetles

open access: yesBMC Zoology, 2020
Background Postcopulatory mate choice occurs ubiquitously in the animal kingdom. However, it is usually a major challenge to visualise the process taking place in a body. This fact makes it difficult to understand the mechanisms of the process.
Yoko Matsumura   +3 more
doaj   +1 more source

Natural Morphology

open access: yes, 2018
Natural Morphology offers a fairly elaborated model for analyzing and interpreting morphological facts, which heavily relies on the one hand on a semiotic foundation of the linguistic sign and on the other on a comprehensive understanding of the cognitive, typological, and system-specific aspects of natural languages.
openaire   +3 more sources

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