Results 91 to 100 of about 4,305,036 (352)

Skyrmion morphology in ultrathin magnetic films

open access: yes, 2017
Nitrogen-vacancy magnetic microscopy is employed in quenching mode as a non-invasive, high resolution tool to investigate the morphology of isolated skyrmions in ultrathin magnetic films.
Akhtar, W.   +10 more
core   +2 more sources

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

Prospects for the use of sialylated immunoglobulins in the treatment of different diseases

open access: yesФундаментальная и клиническая медицина, 2020
The central role of glycosylation has been well confirmed in numerous studies. In particular, a change in the glycosylation profile of antibodies is observed in infectious diseases, autoimmune disorders and cancer.
Yu. V. Markina   +3 more
doaj   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Statistical Physics of Fracture Surfaces Morphology

open access: yes, 2005
Experiments on fracture surface morphologies offer increasing amounts of data that can be analyzed using methods of statistical physics. One finds scaling exponents associated with correlation and structure functions, indicating a rich phenomenology of ...
A. A. Griffith   +49 more
core   +1 more source

A Morphology-Aware Network for Morphological Disambiguation

open access: yesProceedings of the AAAI Conference on Artificial Intelligence, 2016
Agglutinative languages such as Turkish, Finnish andHungarian require morphological disambiguation beforefurther processing due to the complex morphologyof words. A morphological disambiguator is usedto select the correct morphological analysis of a word.Morphological disambiguation is important because itgenerally is one of the first ...
Yildiz, Eray   +4 more
openaire   +3 more sources

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

Morphological Analysis [PDF]

open access: yes, 1999
Chapter 12 In the previous chapters, we have seen that a lot of information about the potential tags of tokens in a text is found by lexicon lookup. Another, often complementary source of information is morphological analysis, i.e. the process of decomposing words into their constituents. The information about the individual constituents can be used to
openaire   +2 more sources

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

TRAIL Activates a Caspase 9/7-Dependent Pathway in Caspase 8/10-Defective SK-N-SH Neuroblastoma Cells with Two Functional End Points: Induction of Apoptosis and PGE2 Release

open access: yesNeoplasia: An International Journal for Oncology Research, 2003
Most neuroblastoma cell lines do not express apical caspases 8 and 10, which play a key role in mediating tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) cytotoxicity in a variety of malignant cell types.
Giorgio Zauli   +6 more
doaj   +1 more source

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