Results 61 to 70 of about 4,215,669 (358)

SIMULTANEOUS IDENTIFICATION OF VESSELS AND MAST CELLS BY DOUBLE IMMUNOSTAINING IN GASTRIC MALIGNANT TUMORS [PDF]

open access: yesResearch and Clinical Medicine, 2018
Objective. To assess the microvessel and mast cell density in gastric tumors, and to evaluate the possible correlation between them. Material and method.
PUSA NELA GAJE   +2 more
doaj  

Expression of immunoglobulins in human epithelial tumors and their potential role in carcinogenesis

open access: yesБюллетень сибирской медицины, 2021
The traditional view of immunoglobulin (Ig) production only by B-lymphocytes and plasma cells has been revisited. Non-lymphoid tumor cells can also synthesize and secrete Ig with unidentified specificity.
K. A. Artemyeva   +3 more
doaj   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

The exon junction complex factor Y14 is dynamic in the nucleus of the beetle Tribolium castaneum during late oogenesis

open access: yesMolecular Cytogenetics, 2017
Background The oocyte chromosomes of the red flour beetle, Tribolium castaneum, are gathered into a knot, forming a karyosphere at the diplotene stage of meiotic prophase.
Artem M. Kiselev   +6 more
doaj   +1 more source

Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation

open access: yesFEBS Letters, EarlyView.
The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen   +2 more
wiley   +1 more source

ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling

open access: yesFEBS Letters, EarlyView.
In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li   +3 more
wiley   +1 more source

Ultrafine Metallic Particles as Inducers of Digestive Processes in Rumen: Dry Matter Digestibility of Feed and Enzymatic Activity

open access: yesScientifica
The ban on the use of antibiotics in animal husbandry encourages an active search for highly effective alternatives with additional properties, one of which is ultrafine particles (UFP) of metallic nature.
Daniil E. Shoshin   +5 more
doaj   +1 more source

Solvent Additives: Key Morphology‐Directing Agents for Solution‐Processed Organic Solar Cells

open access: yesAdvances in Materials, 2018
Organic photovoltaics (OPV) have the advantage of possible fabrication by energy‐efficient and cost‐effective deposition methods, such as solution processing.
Caitlin McDowell   +3 more
semanticscholar   +1 more source

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

open access: yesFEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan   +2 more
wiley   +1 more source

Soft micromachines with programmable motility and morphology

open access: yesNature Communications, 2016
Nature provides a wide range of inspiration for building mobile micromachines that can navigate through confined heterogenous environments and perform minimally invasive environmental and biomedical operations.
Hen-Wei Huang   +4 more
semanticscholar   +1 more source

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