Results 51 to 60 of about 1,102,575 (306)

ASTROCYTOMAS AND PROGNOSIS-FROM MORPHOLOGY TO TUMOR BIOLOGY [PDF]

Medical Journal Armed Forces India, 2000
Twenty-seven cases of Astrocytoma were studied to assess the role of a newly introduced proliferation marker-Proliferating Cell Nuclear Antigen (PCNA) in improving prognostic accuracy in comparison to traditional histologic methods like grading. The study revealed a direct correlation between grading and PCNA expression as determined by labelling ...
Ritu, Lakhtakia, Arti, Trehan, Ramji, Rai, S, Mukherjee   +3 more
openaire   +2 more sources

Introduction to Zoology. T. H. Savory. New York: Philosophical Library, 1968. viii, 239 pp. $6.00. [PDF]

, 2017
Excerpt: This book would delight the traditional zoologist as its emphasis is on systematics and evolution. primarily based on morphology. By the author\u27s own admission he neglects areas concerning histology, embryology, physiology and genetics, while
Nelson, Sigurd, Jr.
core   +3 more sources

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

A new fireworm (Amphinomidae) from the Cretaceous of Lebanon identified from three-dimensionally preserved myoanatomy [PDF]

, 2015
© 2015 Parry et al. Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in ...
A Filippova, A Filippova, A Tzetlin, A Tzetlin, AA Hay, C Helm, D Eibye-Jacobsen, D Eibye-Jacobsen, D Grimaldi, Dan Sykes, DEG Briggs, E Borda, F Pleijel, G Bracchi, G Purschke, G Purschke, G Rouse, GE Budd, Gregory D. Edgecombe, GW Rouse, H Hausen, I Thompson, J Vinther, J Vinther, Jakob Vinther, JR Marsden, JR Marsden, L Feldkamp, L Parry, L Parry, Luke A. Parry, M Imajima, M Müller, MD Sutton, P Chellouche, Paul Wilson, PH Bitter von, PR Wilby, S Conway Morris, S Conway Morris, U Farrell   +40 more
core   +2 more sources

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Chromosomal diversification and karyotype evolution of diploids in the cytologically diverse genus Prospero (Hyacinthaceae) [PDF]

, 2013
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work ...
Andrew R Leitch, Eva M Temsch, Franz Speta, Hanna Weiss-Schneeweiss, Jang, Tae-Soo, John Parker, Khatere Emadzade, Tae-Soo Jang   +7 more
core   +2 more sources

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

TICAL - a web-tool for multivariate image clustering and data topology preserving visualization [PDF]

, 2011
In life science research bioimaging is often used to study two kinds of features in a sample simultaneously: morphology and co-location of molecular components.
Abouna, Sylvie, Khan, Michael, Kölling, Jan, Langenkämper, Daniel, Nattkemper, Tim W., Niehaus, Karsten   +5 more
core  

Assortative Mating By Diet In A Phenotypically Unimodal But Ecologically Variable Population Of Stickleback [PDF]

, 2008
Speciation with gene flow may be driven by a combination of positive assortative mating and disruptive selection, particularly if selection and assortative mating act on the same trait, eliminating recombination between ecotype and mating type ...
Bolnick, Daniel I., Snowberg, Lisa K.
core   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source