Results 51 to 60 of about 1,090,581 (353)

Mitochondrial fatty acid oxidation is stimulated by red light irradiation

FEBS Letters, EarlyView.
Light at different wavelengths has distinct effects on keratinocyte viability and metabolism. UVA light abrogates metabolic fluxes. Blue and green light have no effect on metabolic fluxes, while red light enhanced oxidative phosphorylation by promoting fatty acid oxidation. Keratinocytes are the primary constituents of sunlight‐exposed epidermis.
Manuel Alejandro Herrera, Camille C. Caldeira da Silva, Maiza Von Dentz, Mauricio S. Baptista, Alicia J. Kowaltowski   +4 more
wiley   +1 more source

Computational modeling to elucidate molecular mechanisms of epigenetic memory

, 2015
How do mammalian cells that share the same genome exist in notably distinct phenotypes, exhibiting differences in morphology, gene expression patterns, and epigenetic chromatin statuses?
Alsing, Andrews, Ang, Angel, Arnold, Bannister, Barth, Beisel, Benecke, Bhattacharya, Binder, Black, Buscaino, Bushey, Canzio, Cowieson, David-Rus, Dayarian, Deal, Dodd, Fonseca, Freddolino, Gaffney, Grauffel, Greer, Grewal, Grigoryev, Hanna, Hathaway, Henikoff, Herranz, Hodges, Jacobs, Korolev, Korolev, Kouzarides, Ku, Kulaeva, Lin, Margreitter, Margueron, Mendenhall, Muller, Papp, Pasque, Peinado, Piana, Potoyan, Prohaska, Raghavan, Rohlf, Sanbonmatsu, Sanli, Schwab, Schwammle, Sedighi, So, Sontag, Steffen, Takahashi, Teif, Thon, Wocjan, Xu, Yang, Yuan, Zee, Zhang, Zhang   +68 more
core   +1 more source

Vacuolar transport and function of Saccharomyces cerevisiae sterol ester hydrolase Tgl1

FEBS Letters, EarlyView.
Tgl1, one of yeast sterol ester hydrolases, had been found on the lipid droplets where sterol esters are mainly stored. This study revealed that Tgl1 is transported into the vacuole depending on the ESCRT‐I–III complex, and that it exhibits intra‐vacuolar sterol ester hydrolase activity.
Takumi Nakatsuji, Kosuke Shiraishi, Chuqian Wang, Hiroya Yurimoto, Yasuyoshi Sakai, Masahide Oku   +5 more
wiley   +1 more source

Transmission-Blocking Vaccines for Canine Visceral Leishmaniasis: New Progress and Yet New Challenges

Vaccines, 2023
Dogs with visceral leishmaniasis play a key role in the transmission cycle of Leishmania infantum to humans in the urban environment. There is a consensus regarding the importance of developing a vaccine to control this disease.
Jaqueline Costa Leite, Ana Alice Maia Gonçalves, Diana Souza de Oliveira, Lucilene Aparecida Resende, Diego Fernandes Vilas Boas, Helen Silva Ribeiro, Diogo Fonseca Soares Pereira, Augusto Ventura da Silva, Reysla Maria da Silveira Mariano, Pedro Campos Carvalhaes Reis, Eiji Nakasone Nakasone, João Carlos França-Silva, Alexsandro Sobreira Galdino, Paulo Ricardo de Oliveira Paes, Marília Martins Melo, Edelberto Santos Dias, Miguel Angel Chávez-Fumagalli, Denise da Silveira-Lemos, Walderez Ornelas Dutra, Rodolfo Cordeiro Giunchetti   +19 more
doaj   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

FEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue, Sandrine Picaud, Régine Hepp, Stéphanie Pons, Uwe Maskos, Bertrand Lambolez, Ludovic Tricoire   +6 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

TICAL - a web-tool for multivariate image clustering and data topology preserving visualization [PDF]

, 2011
In life science research bioimaging is often used to study two kinds of features in a sample simultaneously: morphology and co-location of molecular components.
Abouna, Sylvie, Khan, Michael, Kölling, Jan, Langenkämper, Daniel, Nattkemper, Tim W., Niehaus, Karsten   +5 more
core  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

First Record of Huchen hucho hucho (Linnaeus 1758) in the Grza River: Human-Caused Introduction from its Native Habitat in Serbia

Croatian Journal of Fisheries
Huchen or Danube salmon Hucho hucho (Linnaeus 1758) is one of the largest salmonid species in the world and the largest species native to the Danube basin in Europe. In Serbia, this species inhabits the Drina river system, as well as the upper reaches of
Sokolović Vojislav D., Marić Ana D., Nikolić Vera P., Kanjuh Tamara A., Škraba Jurlina Dubravka V., Simonović Predrag D.   +5 more
doaj   +1 more source

Seasonal variation of mortality, detectability, and body condition in a population of the adder (Vipera berus)

Ecology and Evolution, 2019
We analyzed seasonal variation in mortality rates in adult males and females of the European adder (Vipera berus), using data collected during a 13‐year capture–recapture study (2005–2017) in a large population.
Dirk Bauwens, Katja Claus
doaj   +1 more source