Modelling distributed lag effects in epidemiological time series studies [PDF]
The paper argues that much of the existing literature on air pollution and mortality deals only with the transient effects of air pollution. Policy, on the other hand, needs to know when, whether and to what extent pollution-induced increases in ...
Maddison, D.
core
The credibility of health economic models for health policy decision-making: the case of population screening for abdominal aortic aneurysm [PDF]
<i>Objectives</i>: To review health economic models of population screening for abdominal aortic aneurysm (AAA) among elderly males and assess their credibility for informing decision-making. <i>Methods</i>: A literature review
Briggs, A.H. +4 more
core +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Ensemble Modelling for Predicting Fish Mortality
This paper proposes a novel ensemble approach, integrating Artificial Neural Networks (ANNs), Symbolic Regression (SR), and Decision Trees (DTs), to predict fish mortality caused by infectious diseases.
Theofanis Aravanis +2 more
doaj +1 more source
Modelling Hen Harrier Dynamics to Inform Human-Wildlife Conflict Resolution : A Spatially-Realistic, Individual-Based Approach [PDF]
Peer reviewedPublisher ...
Heinonen, Johannes P. M. +3 more
core +3 more sources
ARMA Models for Mortality Forecast
In the last several decades, many countries have been paying a lot of attention to mortality forecastingbecause of high longevity risk. The purpose of this paper is to analyze mortality characteristics of Baltic countries andmake predictions using ARMA models.
Šiškina, Natalja, Šiaulys, Jonas
openaire +5 more sources
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Modelling Mortality from Self-Reported Health and Disability Data: A Multi-Scale Report from Ireland, 2011-2016 / Modelos de Mortalidad a Partir de Datos de Salud y Discapacidad Autopercibidos: Un Informe sobre Irlanda a Distintas Escalas 2011-2016 [PDF]
Relationships between mortality and morbidity are long established within geo-spatial modelling and GIS-based analyses. While there has always been a strong associational relationship between the two measures, this has been less tested at an aggregate ...
Ronan Foley
doaj +1 more source
PICALM::MLLT10 translocated leukemia
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source

