Results 41 to 50 of about 791,636 (297)

Long-Term Durability and Public Health Impact of City-Wide wMel Wolbachia Mosquito Releases in Niterói, Brazil, During a Dengue Epidemic Surge

Tropical Medicine and Infectious Disease
In 2024, the Americas experienced the largest dengue outbreak on record and Brazil was among the worst affected countries, reporting 6.6 million cases and 6200 deaths.
Katherine L. Anders, Gabriel Sylvestre Ribeiro, Renato da Silva Lopes, Pilar Amadeu, Thiago Rodrigues da Costa, Thais Irene Souza Riback, Karlos Diogo de Melo Chalegre, Wesley Pimentel de Oliveira, Cátia Cabral da Silva, Marcos Vinicius Ferreira Mendes Blanco, Ana Lucia Fontes Eppinghaus, Fabio Villas Boas, Tibor Frossard, Benjamin R. Green, Scott L. O’Neill, Peter A. Ryan, Cameron P. Simmons, Luciano A. Moreira   +17 more
doaj   +1 more source

Cloning, expression, purification, and structural modeling of the Chandipura virus matrix protein

FEBS Open Bio, EarlyView.
This research protocol offers a guide for the cloning, expression, and purification of the Chandipura virus matrix protein using E. coli. It also includes a step‐by‐step procedure for cloning, expressing, and conducting fluorescence imaging of GFP‐fused Chandipura virus matrix protein in mammalian cell lines.
Mariana Grieben
wiley   +1 more source

Detecting Dengue in Flight: Leveraging Machine Learning to Analyze Mosquito Flight Patterns for Infection Detection

Advanced Biology, EarlyView.
Dengue infection alters mosquito flight behavior, enabling detection using machine learning classifiers. This study analyzes 3D flight trajectories and evaluates multiple models, showing that longer sequence lengths improve classification performance.
Nouman Javed, Adam J. López‐Denman, Prasad N. Paradkar, Asim Bhatti   +3 more
wiley   +1 more source

Diuresis and α-glucosidase inhibition by erythritol in Aedes aegypti (Diptera: Culicidae) and viability for efficacy against mosquitoes

Parasites & Vectors
Background Sugar alcohols, such as erythritol, are low-impact candidates for attractive toxic sugar baits (ATSB) to kill mosquitoes. To determine whether erythritol has a viable future in ATSB formulations, a suite of assays was conducted to diagnose ...
Irvane E. Nelson, Kobi A. Baker, Ary Faraji, Gregory S. White, Christopher S. Bibbs   +4 more
doaj   +1 more source

Next‐Generation Bio‐Reducible Lipids Enable Enhanced Vaccine Efficacy in Malaria and Primate Models

Advanced Functional Materials, EarlyView.
Structure–activity relationship (SAR) optimization of bio‐reducible ionizable lipids enables the development of highly effective lipid nanoparticle (LNP) mRNA vaccines. Lead LNPs show superior tolerability and antibody responses in rodents and primates, outperforming approved COVID‐19 vaccine lipids.
Ruben De Coen, Sabah Kasmi, Shrinivas Dumbre, Lies Baekens, Elise Seynaeve, Louise Van den Hauwe, Niccolò Cantini, Aello Garantoudi, Filipe Branco Madeira, Alain Marrot, Emma Tuypens, Sofie Seghers, Anna Kuchmiy, Elisabeth Brabants, Bart Vanderborght, Ine Maes, Sarah Vandenberghe, Jessica Filtjens, Alícia Gordún Peiró, Daliya Kancheva, Ayla Debraekeleer, Florence Lambolez, Emily De Lombaerde, Yong Chen, Rafael Miyazawa Martins, Pauline Formaglio, Damya Laoui, Sofie Deschoemaeker, Bruno G. De Geest, Rogerio Amino, Stefaan De Koker   +30 more
wiley   +1 more source

The impact of city-wide deployment of Wolbachia-carrying mosquitoes on arboviral disease incidence in Medellín and Bello, Colombia: study protocol for an interrupted time-series analysis and a test-negative design study

F1000Research, 2020
Background: Dengue, chikungunya and Zika are viral infections transmitted by Aedes aegypti mosquitoes, and present major public health challenges in tropical regions.
Estefanía Muñoz, Suzanne M Dufault, Eduardo Santacruz, Ivan D. Velez, Sandra L. Duque, Simon C. Kutcher, Jovany Barajas, Alexander Uribe, Ana Cristina Patino, Sandra Gonzalez, Luis Martínez, Lina Zuluaga, María Patricia Arbelaez, María Camila Mejia, Nicholas P. Jewell, Henry Pulido, Cameron P. Simmons, Scott L. O'Neill, Stephanie K. Tanamas, Katherine L. Anders   +19 more
doaj  

Disruption of spatiotemporal clustering in dengue cases by wMel Wolbachia in Yogyakarta, Indonesia

Scientific Reports, 2022
Dengue exhibits focal clustering in households and neighborhoods, driven by local mosquito population dynamics, human population immunity, and fine scale human and mosquito movement.
Suzanne M. Dufault, Stephanie K. Tanamas, Citra Indriani, Adi Utarini, Riris Andono Ahmad, Nicholas P. Jewell, Cameron P. Simmons, Katherine L. Anders   +7 more
doaj   +1 more source

Recent Advances in Reactive Microdroplets for Clean Water and Energy

Advanced Materials, EarlyView.
Reactive microdroplets enable precise and sustainable chemistry at small scales. This review explores their role as confined reactors and dynamic interfaces for synthesizing functional materials, fuels, and microdevices. It offers a critical perspective on how droplet‐based platforms can drive next‐generation technologies in clean energy, environmental
Qiuyun Lu, Boubakar Sanogo, Tanay Kumar, Ben Bin Xu, Xuehua Zhang   +4 more
wiley   +1 more source

Mosquito Trypanosomes [PDF]

Journal of Hygiene, 1906
In a previous paper on Bird Trypanosomes it was pointed out that these organisms grew readily in the test-tube on blood agar and that the resulting forms resembled the flagellates which Schaudinn found in the gut of mosquitoes which had fed on owls infected with Halteridium and with H. Ziemanni.
Novy, F. G., Macneal, W. J., Torrey, H. N.   +2 more
openaire   +2 more sources

Neuroimmune Microenvironment Reprogramming via Immuno‐piezoelectric Transducers for Synergistic Stem Cell Therapy in Traumatic Brain Injury

Advanced Materials, EarlyView.
A novel immuno‐piezoelectric transducer is innovatively developed. This device promotes neural stem cell (NSC) differentiation and maturation via ultrasound‐induced electrical stimulation and it amplifies the therapeutic efficacy of NSC in traumatic brain injury (TBI) by modulating the immune microenvironment. This piezoelectric transducer with “immune‐
Linlin Liang, Xin Li, Kai Hu, Pingqiang Cai, Jianwu Wang, Jing Yu, Shasha Wang, Yuwei Zhao, Changgeng Xu, Siwei Li, Hong Liu, Changyong Wang, Jin Zhou   +12 more
wiley   +1 more source