Results 111 to 120 of about 730,542 (336)
Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren+16 more
wiley +1 more source
STUDIES ON THE MOTILITY OF THE HUMAN UTERUS IN VIVO [PDF]
Leo Wilson, Raphael Kurzrok
openalex +1 more source
Approximately 20 years have passed since the first isolation of tubulin, dynein and non-muscle actomyosin. During this period actomyosin, microtubule-dynein or microtubules plus other ATPases (kinesin) have been implicated in almost all cellular motile phenomena.
openaire +2 more sources
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song+11 more
wiley +1 more source
P-27 CELLULAR EFFECTS OF IN VITRO LIPID OVERLOAD ON HEPATIC STELLATE CELLS AND HEPATOCYTES.
Introduction and Objectives: Hepatic cells undergo different processes in response to the steatogenic input of MAFLD. Hepatic cell culture in steatogenic medium is a useful, reproducible tool intended to elucidate these pathogenic mechanisms.
Adriana Campos-Espinosa+3 more
doaj
Management of Barrett's esophagus: Screening to newer treatments
Barrett's esophagus is a premalignant condition of the esophagus in which the squamous epithelium of the lower end of the esophagus is replaced with columnar epithelium.
V. Thoguluva Chandrasekar+2 more
doaj +1 more source
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop+10 more
wiley +1 more source
The Diagnosis and Treatment of Infantile Nystagmus Syndrome (INS)
The successful treatment of infantile nystagmus syndrome (INS) depends primarily on accurate and repeatable diagnosis of the type(s) of nystagmus present as well as their variation with gaze and convergence angles or fixating eye.
Sangeeta Khanna, Louis F. Dell'Osso
doaj +1 more source
Flagellar motility is mutagenic
Flagella are highly complex rotary molecular machines that enable bacteria to not only migrate to optimal environments but also to promote range expansion, competitiveness, virulence, and antibiotic survival. Flagellar motility is an energy-demanding process, where the sum of its production (biosynthesis) and operation (rotation) costs has
Souvik Bhattacharyya+3 more
openaire +3 more sources
Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias+12 more
wiley +1 more source