Results 141 to 150 of about 731,626 (335)
The role of circular RNAs in regulating cytokine signaling in cancer
Cytokines present in the tumor microenvironment fuel cancer development. Aberrant expression of circRNAs contributes to cancer progression. Cytokines are involved in regulating circRNA biogenesis. Furthermore, aberrantly expressed circRNAs regulate the expression of ligands, receptors, and downstream effectors involved in cytokine signaling to promote ...
Vandana Joshi+4 more
wiley +1 more source
Introduction and Objectives: The cure for chronic Hepatitis C (HCV) is a milestone for humanity, however, patients could still progress toward hepatocellular carcinoma even after receiving direct-acting antiviral treatment [1]. Therefore, determining the
Abigail Hernandez-Barragan+11 more
doaj +1 more source
The survival of motility in mammalian spermatozoa
Charles George Lewis Wolf
openalex +2 more sources
In the blood–testis barrier, occludin is crucial for tight junctions. This study demonstrates that occludin‐targeting short peptides disrupt junction integrity, inducing immune cell infiltration, tumor necrosis factor‐α/interleukin‐6 secretion and mitochondrial dysfunction, ultimately triggering apoptosis.
Heng Wang, Xiaofang Tan, Deyu Chen
wiley +1 more source
THE EFFECTS OF SEVERAL AMINES ON THE INTESTINAL MOTILITY AND ON THE HISTAMINE ACTION
Osamu Yagasaki, K. TAKENO, I. YANAGIYA
openalex +2 more sources
GASTRIC MOTILITY AND THE VOLUME OF GASTRIC SECRETION IN MAN [PDF]
Arthur L. Bloomfield, Chester S. Keefer
openalex +1 more source
Cleavable N‐terminal Thioredoxin fusion enabled soluble expression and purification of otherwise insoluble SARS‐CoV‐2 Nucleocapsid (N) protein. A four‐step purification strategy yielded highly homogeneous, RNA‐free N protein. Binding assays showed high RNA affinity (Kd ~ 28 nm). The study will facilitate high‐resolution structural studies of N protein,
Shweta Singh, Gagan D. Gupta
wiley +1 more source
Genetic diversity and population structure of the Taigan dog breed
The Taigan is a rare sighthound from the mountains of Kyrgyzstan. We used DNA markers to study its genetic diversity and compare it with other sighthound breeds. Our findings show that the Taigan shares close genetic ties with the Kazakh Tazy, suggesting a common ancestry shaped by nomadic traditions and regional adaptation.
Kira Bespalova+10 more
wiley +1 more source
IGFBPs in chronic liver diseases: Are they potential biomarkers?
Introduction and objectives: Liver diseases are caused by alcohol consumption, Hepatitis C virus, and metabolic dysfunction. There are few studies on insulin-like growth factor binding proteins (IGFBPs), also IGFBP-1 being involved in regulating glucose ...
Marisela Hernandez-Santillan+9 more
doaj +1 more source
Functional parameters of spermatozoa obtained by a new selection device
This study compares density gradient centrifugation and the LensHooke CA0™ device for sperm separation. DGC requires multiple steps, specialized equipment, and technical expertise. In contrast, the CA0 device offers key practical and methodological advantages, resulting in a faster, simpler, and more affordable sperm selection method.
Julio C. Chávez+8 more
wiley +1 more source