Results 141 to 150 of about 424,553 (315)

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Epididymal macrophage senescence contributes to sperm motility decrease upon environmental stress. [PDF]

Sci Adv
Wang XR, Li H, Xiong YW, Yuan Z, Cheng XY, Hu YF, He XJ, Fan LL, Luo YX, Sun J, Sun CF, Zhang XX, Wang Y, Lu Q, Wang KW, Tan LL, Jiang XH, Zhu HL, Xu DX, Wang H.   +19 more
europepmc   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

Aging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

Efficacy and Safety of Glucagon-Like Peptide-1 Receptor Agonists for Obesity Management in Adults With and Without Type 2 Diabetes: A Systematic Review

Journal of Obesity
Jena Velji-Ibrahim, Dhruvil Radadiya, Kalpit Devani, Harsh Patel, Piyush Nathani, Cesare Hassan, Nicola Pugliese, Christopher Thompson, Prateek Sharma   +8 more
doaj   +1 more source

Sustained soluble adenylyl cyclase (sAC)-generated cAMP is necessary and sufficient for hyperactivated motility in human sperm. [PDF]

Hum Reprod
Ritagliati C, Devine F, Buck J, Levin LR.   +3 more
europepmc   +1 more source

Gastric motility is an important area for endoscopic research

, 1984
H Barowsky
openalex   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

Anti-Müllerian Hormone as a Marker for Castration Status and Fertility in Bulls and Oxen. [PDF]

Reprod Domest Anim
Gilg D, Otzdorff C, Zablotski Y, Zerbe H, Walter B.   +4 more
europepmc   +1 more source

Effects of GM-611, a novel erythromycin derivative, on gastrointestinal motility and gastric emptying in dogs.

, 1994
Hisanori Takanashi, Kenji Yogo, Michitaka Akima, Hiroshi Koga, Hiroyuki Nabata   +4 more
openalex   +1 more source