Clinically relevant enhancement of human sperm motility using compounds with reported phosphodiesterase inhibitor activity [PDF]
STUDY QUESTION: Can we identify compound(s) with reported phosphodiesterase inhibitor (PDEI) activity that could be added to human spermatozoa in vitro to enhance their motility without compromising other sperm functions?
Alasmari+54 more
core +5 more sources
Motility-driven glass and jamming transitions in biological tissues. [PDF]
Cell motion inside dense tissues governs many biological processes, including embryonic development and cancer metastasis, and recent experiments suggest that these tissues exhibit collective glassy behavior.
Dapeng Bi+5 more
semanticscholar +1 more source
Clustering of bacteria with heterogeneous motility [PDF]
We study the clustering of a model cyanobacterium \textit{Synechocystis} into microcolonies. The bacteria are allowed to diffuse onto surfaces of different hardness, and interact with the others by aggregation and detachment. We find that soft surfaces give rise to more microcolonies than hard ones. This effect is related to the amount of heterogeneity
arxiv +1 more source
Spontaneous membrane formation and self-encapsulation of active rods in an inhomogeneous motility field [PDF]
We study the collective dynamics of self-propelled rods in an inhomogeneous motility field. At the interface between two regions of constant but different motility, a smectic rod layer is spontaneously created through aligning interactions between the ...
Grauer, Jens+2 more
core +2 more sources
To the Editor: —In the Current Comment on "The Function of the Prostate" (The Journal, Feb. 17, 1917, p. 553), it is stated that "it has been noted that the spermatozoa are practically motionless while in the seminiferous tubules of the testis, but become actively motile in the vas deferens, or when mixed with prostatic secretion." The statement that
openaire +2 more sources
Effect of motility on the transport of bacteria populations through a porous medium [PDF]
The role of activity on the hydrodynamic dispersion of bacteria in a model porous medium is studied by tracking thousands of bacteria in a microfluidic chip containing randomly placed pillars. We first evaluate the spreading dynamics of two populations of motile and non-motile bacteria injected at different flow rates.
arxiv +1 more source
Effects of in vitro lipid overload on LX-2 hepatic stellate cells
Introduction and Objectives: Studying lipid overload repercussions on hepatic stellate cells (HSC) is of great importance due to their role in fibrosis during NAFLD. Steatogenic cell culture of HSC is intended to elucidate pathogenic mechanisms in NAFLD.
A Campos-Espinosa+2 more
doaj
Dynamic clustering of passive colloids in dense suspensions of motile bacteria [PDF]
Mixtures of active and passive particles are predicted to exhibit a variety of nonequilibrium phases. Here we report a dynamic clustering phase in mixtures of colloids and motile bacteria. We show that colloidal clustering results from a balance between bond breaking due to persistent active motion and bond stabilization due to torques that align ...
arxiv +1 more source
A European Approach to Irritable Bowel Syndrome Management
Irritable bowel syndrome (IBS) is characterized by a number of clinical features and probably comprises a cluster of different conditions. The most frequent symptom reported by IBS patients is abdominal pain, although for a number of patients, bowel ...
Michel Delvaux, Jacques Frexinos
doaj +1 more source
Tree of motility – A proposed history of motility systems in the tree of life
Motility often plays a decisive role in the survival of species. Five systems of motility have been studied in depth: those propelled by bacterial flagella, eukaryotic actin polymerization and the eukaryotic motor proteins myosin, kinesin and dynein ...
M. Miyata+27 more
semanticscholar +1 more source