Transcriptome profiling reveals significant changes in the gastric muscularis externa with obesity that partially overlap those that occur with idiopathic gastroparesis [PDF]
, 2019 BACKGROUND: Gastric emptying is impaired in patients with gastroparesis whereas it is either unchanged or accelerated in obese individuals. The goal of the current study was to identify changes in gene expression in the stomach muscularis that may be ...
Chen, Meng +7 more
core +1 more source
Frontiers in NeurologyIntroductionThis study proposes a deep learning–based image analysis method for automated scoring of the severity of horizontal ocular movement disorders and evaluates its performance against traditional manual scoring methods.MethodsA total of 2,565 ...
Xiao-lu Jin +4 more
doaj +1 more source
Nucleotide-free structures of KIF20A illuminate atypical mechanochemistry in this kinesin-6
Open Biology, 2023 KIF20A is a critical kinesin for cell division and a promising anti-cancer drug target. The mechanisms underlying its cellular roles remain elusive. Interestingly, unusual coupling between the nucleotide- and microtubule-binding sites of this kinesin-6 ...
Fanomezana Moutse Ranaivoson +12 more
doaj +1 more source
A self-driven phase transition drives Myxococcus xanthus fruiting body formation [PDF]
, 2019 Combining high-resolution single cell tracking experiments with numerical simulations, we show that starvation-induced fruiting body (FB) formation in Myxococcus xanthus is a phase separation driven by cells that tune their motility over time.
Bahar, Fatmagul +7 more
core +2 more sources
Activation of Ciona sperm motility: phosphorylation of dynein polypeptides and effects of a tyrosine kinase inhibitor [PDF]
, 1991 A high molecular mass dynein ATPase polypeptide and a 18–20 kDa dynein light chain of Ciona sperm flagella are phosphorylated during in vivo activation of motility or in vitro activation of motility by incubation with cyclic AMP.
Brokaw, Charles J., Dey, Chinmoy S.
core
Spontaneous symmetry breaking in active droplets provides a generic route to motility
, 2012 We explore a generic mechanism whereby a droplet of active matter acquires motility by the spontaneous breakdown of a discrete symmetry. The model we study offers a simple representation of a "cell extract" comprising, e.g., a droplet of actomyosin ...
Cates, M. E., Marenduzzo, D., Tjhung, E.
core +1 more source
Tyrosine phosphorylation of cortactin by the FAK-Src complex at focal adhesions regulates cell motility. [PDF]
, 2011 BackgroundCell migration plays an important role in many physiological and pathological processes, including immune cell chemotaxis and cancer metastasis.
Liao, Kan, Liu, Yang, Wang, Wenqi
core +2 more sources
Network topology drives population temporal variability in experimental habitat networks
Population Ecology, EarlyView.Habitat patches connected by dispersal pathways form habitat networks. We explored how network topology affects population outcomes in laboratory experiments using a model species (Daphnia carinata). Central habitat nodes in complex lattice networks exhibited lower temporal variability in population sizes, suggesting they support more stable ...
Yiwen Xu +3 more
wiley +1 more source
Atomic Force Microscopy of height fluctuations of fibroblast cells [PDF]
, 2002 We investigated the nanometer scale height fluctuations of 3T3 fibroblast cells with the atomic force microscope (AFM) under physiological conditions. Correlation between these fluctuations and lateral cellular motility can be observed.
A. Czirók +31 more
core +2 more sources
Geographic variation in walking activity in the red flour beetle Tribolium castaneum
Population Ecology, EarlyView.This study examined whether there is geographic variation in field populations, focusing on the moving activity in the red flour beetle Tribolium castaneum. Results showed significant differences in moving activity among field populations but no correlation with latitude or meteorological factors.
Kentarou Matsumura
wiley +1 more source