Results 61 to 70 of about 435,922 (318)

Boundedness and Exponential Stabilization in a Parabolic-Elliptic Keller--Segel Model with Signal-dependent Motilities for Local Sensing Chemotaxis [PDF]

, 2020
Jie Jiang
openalex   +1 more source

The myosin X motor is optimized for movement on actin bundles

Nature Communications, 2016
Myosin X is a molecular motor unique in its ability to generate filopodia, but the mechanism explaining this behaviour is not known. Here, through a combination of structure, single-molecule assays and modelling the authors show that myosin X is ...
Virginie Ropars, Zhaohui Yang, Tatiana Isabet, Florian Blanc, Kaifeng Zhou, Tianming Lin, Xiaoyan Liu, Pascale Hissier, Frédéric Samazan, Béatrice Amigues, Eric D. Yang, Hyokeun Park, Olena Pylypenko, Marco Cecchini, Charles V. Sindelar, H. Lee Sweeney, Anne Houdusse   +16 more
doaj   +1 more source

Automatic diagnosis of extraocular muscle palsy based on machine learning and diplopia images [PDF]

International Journal of Ophthalmology
AIM: To develop different machine learning models to train and test diplopia images and data generated by the computerized diplopia test. METHODS: Diplopia images and data generated by computerized diplopia tests, along with patient medical records, were
Xiao-Lu Jin, Xue-Mei Li, Tie-Juan Liu, Ling-Yun Zhou   +3 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Exposure to outdoor artificial light at night is associated with a higher risk of ulcerative colitis: a prospective cohort study from the UK Biobank

Frontiers in Public Health
BackgroundInflammatory bowel disease (IBD) is a chronic inflammatory condition of the gastrointestinal tract, and environmental factors are believed to play an important role in its pathogenesis.
Jiamiao Chen, Jiamiao Chen, Laifu Li, Laifu Li, Yan Ran, Yan Ran, Zhuoya Sun, Zhuoya Sun, Shiwei Lu, Shiwei Lu, Yan Zhuang, Yan Zhuang, Lianli Wang, Lianli Wang, Yating Sun, Yating Sun, Fei Dai, Fei Dai   +17 more
doaj   +1 more source

The pyruvate generator is a common phenomenon in mitochondria from different rat and mouse brain regions

FEBS Letters, EarlyView.
The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber, Niki Karavasili, Matthias Kunz, Zemfira Gizatullina, Timur Gainutdinov, Stefan Vielhaber, Wolfram S. Kunz, Frank N. Gellerich   +7 more
wiley   +1 more source

Esophageal High Pressure Zones: Effect of Perisophageal Structures on Esophageal Manometric Recording

Canadian Journal of Gastroenterology, 1994
During the course of esophageal motility studies, short zones of elevated esophageal baseline pressure are occasionally noticed. The aim of this study is to determine their frequency and their cause. Among 77 consecutive esophageal manometries (group 1),
G Bédard, A Pellicano, R Ste-Marie
doaj   +1 more source

Cell Motility [PDF]

Journal of Cell Science, 1986
Approximately 20 years have passed since the first isolation of tubulin, dynein and non-muscle actomyosin. During this period actomyosin, microtubule-dynein or microtubules plus other ATPases (kinesin) have been implicated in almost all cellular motile phenomena.
openaire   +2 more sources

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Differences in the progression of liver disease in male and female rats induced by TAA: considerations in the development of pharmacological therapies

Annals of Hepatology
Introduction and Objectives: Thioacetamide (TAA) is a hepatotoxic agent that causes fibrosis, cirrhosis, and cancer. Various doses and regimens of TAA have been tested in different murine models to validate hepatoprotective compounds.
Jesús Dorantes-Alvarez, Moisés Martínez-Castillo, Adrián Flores-Sánchez, Ángel García-López, Luz Castro-Hernández, Abigail Hernandez-Barragan, Marisela Hernández-Santillán, Gabriela Gutierrez-Reyes   +7 more
doaj   +1 more source