Results 41 to 50 of about 723,767 (301)

Jackhammer Esophagus: From Manometric Diagnosis to Clinical Presentation

open access: yesCanadian Journal of Gastroenterology and Hepatology, 2019
Background. Jackhammer esophagus is a hypercontractile esophageal disorder recently brought to light with the advent of high resolution manometry (HRM).
Marianne Clément   +3 more
doaj   +1 more source

Spontaneous symmetry breaking in active droplets provides a generic route to motility

open access: yes, 2012
We explore a generic mechanism whereby a droplet of active matter acquires motility by the spontaneous breakdown of a discrete symmetry. The model we study offers a simple representation of a "cell extract" comprising, e.g., a droplet of actomyosin ...
Cates, M. E., Marenduzzo, D., Tjhung, E.
core   +1 more source

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski   +9 more
wiley   +1 more source

Interactions of Little-brain and Big-brain in Explaining Abdominal Symptoms

open access: yesInternational Journal of Endorsing Health Science Research, 2022
For a long time, the role of an extensive neurological network in the gut (the little-brain) has been under-recognized because the enteric nervous system (ENS) is thought to have little impact beyond digestion.
Yeong Yeh Lee, Naveen Ramasami
doaj   +1 more source

Evidence of the presence of calcium/calmodulin-dependent protein kinase IV in human sperm and its involvement in motility regulation [PDF]

open access: yes, 2005
The mechanisms involved in the regulation of mammalian sperm motility are not well understood. Calcium ions (Ca(2+)) have been suggested to play a key role in the maintenance of motility; nevertheless, how Ca(2+) modulates this process has not yet been ...
Buffone, Mariano Gabriel   +6 more
core   +1 more source

Preferences of Pediatric Patients and Their Caregivers for Chemotherapy‐Induced Nausea and Vomiting Control Endpoints: A Mixed Methods Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Although not always achieved, complete chemotherapy‐induced nausea and vomiting (CINV) control is the conventional goal of CINV prophylaxis. In this two‐center, mixed‐methods study, we sought to understand the preferences of adolescent patients and family caregivers for CINV control endpoints.
Haley Newman   +8 more
wiley   +1 more source

Pulmonary Dysfunction Is Associated With Sleep Study Abnormalities in Children With Sickle Cell Disease: A Multicenter Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Pulmonary dysfunction and sleep abnormalities are common in children with sickle cell disease (SCD) and are associated with worse clinical outcomes. Whether spirometry abnormalities are associated with polysomnography (PSG) findings remains unclear.
Ammar Saadoon Alishlash   +4 more
wiley   +1 more source

MMP1 is a promising prognostic, therapeutic and immunological biomarker for pancreatic cancer: evidence from bioinformatics analysis and biological experiments

open access: yesBMC Cancer
Background Pancreatic cancer remains one of the most lethal malignancies worldwide, underscoring the urgent need for reliable biomarkers to predict prognosis and guide therapy.
Shuhui Wang   +5 more
doaj   +1 more source

A deep learning-based image analysis model for automated scoring of horizontal ocular movement disorders

open access: yesFrontiers in Neurology
IntroductionThis study proposes a deep learning–based image analysis method for automated scoring of the severity of horizontal ocular movement disorders and evaluates its performance against traditional manual scoring methods.MethodsA total of 2,565 ...
Xiao-lu Jin   +4 more
doaj   +1 more source

Quantification of Cell Movement Reveals Distinct Edge Motility Types During Cell Spreading [PDF]

open access: yes, 2007
Actin-based motility is central to cellular processes such as migration, bacterial engulfment, and cancer metastasis, and requires precise spatial and temporal regulation of the cytoskeleton.
Anna H. Shneidman   +8 more
core   +1 more source

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